Bordetella parapertussis Survives inside Human Macrophages in Lipid Raft-Enriched Phagosomes [PDF]
Bordetella parapertussis is a human pathogen that causes whooping cough. The increasing incidence of B. parapertussis has been attributed to the lack of cross protection induced by pertussis vaccines. It was previously shown that B. parapertussis is able
Gorgojo, Juan Pablo+2 more
core +3 more sources
Monoclonal antibody-based therapies for bacterial infections [PDF]
Purpose of review This review highlights recent developments in the development of monoclonal antibodies to treat bacterial disease, including preclinical advances and the status of current clinical trials. Recent findings Monoclonal antibody (mAb) therapy is becoming increasingly ...
Bettina C. Fries+2 more
openaire +3 more sources
Separation and concentration of target bacteria has become essential to sensitive and accurate detection of foodborne bacteria to ensure food safety. In this study, we developed a bacterial separation system for continuous-flow separation and efficient ...
Xiaoting Huo+7 more
doaj +1 more source
The late endocytic Rab39a GTPase regulates the interaction between multivesicular bodies and chlamydial inclusions. [PDF]
Given their obligate intracellular lifestyle, Chlamydia trachomatis ensure their access to multiple host sources of essential lipids by interfering vesicular transport.
Capmany, Anahi+7 more
core +1 more source
Human antibody repertoire frequently includes antibodies to a bacterial biofilm associated protein.
We have previously described a native human monoclonal antibody, TRL1068, that disrupts bacterial biofilms by extracting from the biofilm matrix key scaffolding proteins in the DNABII family, which are present in both gram positive and gram negative ...
Stefan Ryser+3 more
doaj +1 more source
Functional assays to screen and select monoclonal antibodies that target Yersinia pestis
Yersinia pestis is a gram-negative bacterium that causes plague in animals and humans. Depending on the route of disease transmission, the bacterium can cause an acute, often fatal disease that has a narrow window for treatment with antibiotics ...
Sergei S. Biryukov+14 more
doaj +1 more source
Population, sexual and reproductive health, rights and sustainable development: forging a common agenda. [PDF]
This article suggests that sexual and reproductive health and rights activists seeking to influence the post-2015 international development paradigm must work with sustainable development advocates concerned with a range of issues, including climate ...
Campbell, D. M.+11 more
core +1 more source
Detection of Bacterial Pathogens by Phage Antibody Display
Vibrio parahaemolyticus is a halophilic Gramnegative facultative anaerobe commonly found in estuarine waters and in seafood like shellfish. It has been implicated in outbreaks of gastro-enteritis in several countries [1]. Food borne illness caused by V.
Namrata Pai+3 more
openaire +3 more sources
Anti-platelet factor 4/polyanion antibodies mediate a new mechanism of autoimmunity
Antibodies against the platelet factor 4 (PF4) support bacterial host defence but in some cases may lead to heparin-induced thrombocytopenia (HIT).
Thi-Huong Nguyen+3 more
doaj +1 more source
Recent Developments in Antibody-Based Assays for the Detection of Bacterial Toxins
Considering the urgent demand for rapid and accurate determination of bacterial toxins and the recent promising developments in nanotechnology and microfluidics, this review summarizes new achievements of the past five years.
Kui Zhu+4 more
doaj +1 more source