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Antibodies to Canine Helminth Parasites in Asthmatic and Nonasthmatic Children

International Archives of Allergy and Immunology, 1981
We studied the prevalence of IgE and IgG antibodies to <i>Toxocara canis</i> and <i>Dirojilaria immitis</i>, helminth parasites of dogs, in asthmatic and nonasthmatic children born and raised in Hawaii. The serologic pattern of the two groups was found to differ significantly. Of the 80 asthmatic subjects, 45.0% had IgE antibody
R S, Desowitz, R, Rudoy, J W, Barnwell
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The Role of Antibody in Parasitic Helminth Infections

2014
A wealth of data on the protective immune mechanisms induced following helminth infection exist, but how antibody responses protect against helminth infections is unclear and shows variation between species. Understanding antibody responses to different helminth species is important to support the future development of anti-helminth vaccines that will ...
Erin, Logan   +2 more
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The preparation and use of radiolabelled specific Helminth antibodies

The International Journal of Applied Radiation and Isotopes, 1983
Specific antibodies from the serum of sheep infected with Haemonchus contortus were isolated by combination with a “solid phase antigen” (soluble antigen coupled to an activated crystalline cellulose). The antibodies were labelled with 125I while bound to the solid phase then eluted and their potential demonstrated: (1) to determine amounts of specific
M. Movsesijan   +3 more
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Modeling the contribution of antibody attack rates to single and dual helminth infections in a natural system

Mathematical Biosciences, 2023
Within-host models of infection can provide important insights into the processes that affect parasite spread and persistence in host populations. However, modeling can be limited by the availability of empirical data, a problem commonly encountered in natural systems.
Vanalli C.   +5 more
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Antibody to Interleukin-5 Inhibits Helminth-Induced Eosinophilia in Mice

Science, 1989
When rodents are infected with the nematode Nippostrongylus brasiliensis , large numbers of eosinophils appear in their blood and lungs and their serum immunoglobulin E (IgE) is increased. Injection of a monoclonal antibody to interleukin-5 completely suppressed the blood eosinophilia and the infiltration of ...
R L, Coffman   +4 more
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Importance of Antibody Class in Helminth Infections

1989
Antibodies play an important role in the rejection of many parasites. They are essential for immune recognition of antigens incorporated in the surface of large nonphagocytosable helminths. Thus by focusing host defense mechanisms against the intact parasite they may ultimately lead to parasite rejection.
N. M. Almond, R. M. E. Parkhouse
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A theoretical framework for the immunoepidemiology of blocking antibodies to helminth infection

Parasite Immunology, 1994
SUMMARYEpidemiological evidence is widely cited in support of the hypothesis that certain antibody responses to human helminth, especially schistosome, infection exhibit blocking activity. This evidence includes positive correlations between antibody levels and the rate of re‐establishment of infection following chemotherapy, antibody levels which peak
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Reagin-like Antibodies in Animals Immune to Helminth Parasites

Nature, 1964
RECENT investigations here have shown that rats, monkeys and sheep infected with helminth parasites produce an antibody with many of the properties of human reagin. Naturally occurring persistent antibodies of this type have not been demonstrated previously in animals, although in rats an antibody similar in its biological properties but transitory in ...
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