Results 71 to 80 of about 557,652 (221)

Helminth driven gut inflammation and microbial translocation associate with altered vaccine responses in rural Uganda

npj Vaccines
Vaccine responses are sometimes impaired in rural, low-income settings. Helminth-associated gut barrier dysfunction and microbial translocation (MT) may be implicated. We used samples from a trial of praziquantel treatment-effects on vaccine responses in
Jacent Nassuuna, Joas Sterk, Bridgious Walusimbi, Agnes Natukunda, Ronald Nkangi, Rebecca Amongin, Ludoviko Zirimenya, Emily L. Webb, Alison M. Elliott, Gyaviira Nkurunungi   +9 more
doaj   +1 more source

Immunogenicity to the bivalent HPV-16/18 vaccine among adolescent African students exposed to helminths and malaria

Journal of Infection in Developing Countries, 2015
Introduction: Efficacious vaccines that prevent human papillomavirus (HPV) infection, the recognized cause of cervical cancer, are now available. However, in sub-Saharan Africa, immune-modulating infections such as helminths and malaria may affect ...
Miriam Nakalembe, Cecily Banura, Proscovia Bazanye Namujju, Florence Maureen Mirembe   +3 more
doaj   +1 more source

Dual Host–Pathogen Screening of the Lung During Severe Influenza Using Spatial Transcriptomics

Immunology &Cell Biology, EarlyView.
We performed genome‐wide spatial transcriptomics at 10 μm resolution on the lungs of mice infected with influenza A virus. We utilised publicly available scRNAseq reference datasets to identify cell types present. We found viral transcripts across all detected cell types, suggesting localised indiscriminate infection.
Marcus Z. W. Tong, Oliver P. Skinner, Chen Zhu, Brooke J. Wanrooy, Ashlyn S. Kerr, Zheng Ruan, Cameron G. Williams, Heran Zhang, Linda M. Wakim, Ashraful Haque   +9 more
wiley   +1 more source

Gastrointestinal parasites of feral cats from Christmas Island [PDF]

, 2008
Objective To investigate the gastrointestinal parasites present in feral cats on Christmas Island, with particular interest in the protozoan parasite Toxoplasma gondii.
Elliot, A.D., Adams, P.J., Algar, D., Brazell, R.I.   +3 more
core  

Distribution and risk factors for Plasmodium and helminth co-infections: a cross-sectional survey among children in Bagamoyo district, coastal region of Tanzania [PDF]

, 2015
Plasmodium and soil transmitted helminth infections (STH) are a major public health problem, particularly among children. There are conflicting findings on potential association between these two parasites.
Julian Rothen (716976), Abdulla, Salim, Knopp, S., Mohamed, A., Tanner, M., Daubenberger, C., Mohammed, A.S., Omar Lweno, Stefanie Knopp, Ummi Abdul (716974), Salim, N., Daubenberger, Claudia, Tobias Schindler, Abdulla, S., Abdul, Ummi, Denis Kwaba, Blaise Genton, John Masimba, Nahya Salim (716972), Lweno, Omar, John Masimba (716977), Abdul, U., Kwaba, D., Althaus, F., Rothen, J., Stefanie Knopp (108848), Blaise Genton (67109), Lweno, O., Alisa S Mohammed, Genton, B., Claudia Daubenberger, Kwaba, Denis, Denis Kwaba (716978), Julian Rothen, Mohammed, Alisa S., Salim Abdulla, Mohamed, Ali, Althaus, Fabrice, Schindler, T., Schindler, Tobias, Rothen, Julian, Marcel Tanner (33894), Tobias Schindler (716975), Marcel Tanner, Omar Lweno (716973), Salim Abdulla (76158), Ali Mohamed, Masimba, J., Tanner, Marcel, Genton, Blaise, Masimba, John, Fabrice Althaus (716979), Ali Mohamed (3546578), Alisa S. Mohammed (224862), Nahya Salim, Claudia Daubenberger (212658), Salim, Nahya, Fabrice Althaus, Knopp, Stefanie, Ummi Abdul, Kwaba Denis, Althaus Fabrice, Knopp S, Daubenberger Claudia, Mohammed Alisa S., Genton B, Mohammed AS, Abdul Ummi, Abdul U, Tanner Marcel, Salim Nahya, Abdulla Salim, Althaus F, Schindler Tobias, Tanner M, Knopp Stefanie, Mohamed Ali, Daubenberger C, Abdulla S, Rothen Julian, Salim N, Masimba J, Lweno Omar, Lweno O, Mohamed A, Rothen J, Genton Blaise, Schindler T, Kwaba D, Masimba John   +89 more
core   +1 more source

Adaptive Immunity in Marsupials

Journal of Experimental Zoology Part A: Ecological and Integrative Physiology, Volume 345, Issue 9, Page 913-932, November 2026.
Comparison of the marsupial and eutherian adaptive immune systems. ABSTRACT Marsupials diverged from eutherian mammals 125–160 million years ago. Although evolutionarily distinct, both groups of mammals can produce complex adaptive immune responses to antigens with several key differences.
Cassandra L. Jol, Hayley J. Stannard, Julie M. Old   +2 more
wiley   +1 more source

Blockade of IL-33 release and suppression of type 2 innate lymphoid cell responses by helminth secreted products in airway allergy [PDF]

, 2014
Helminth parasites such as the nematode Heligmosomoides polygyrus strongly inhibit T helper type 2 (Th2) allergy, as well as colitis and autoimmunity. Here, we show that the soluble excretory/secretory products of H.
McSorley, H. J.; id_orcid, Smith, K A, Blair, N.F., McSorley, H J, McSorley, H.J., Maizels, R M, McSorley, H. J., Smith, K. A., Smith, K.A., Maizels, R. M., Blair, N F, McKenzie, A.N.J., Blair, N. F., McKenzie, A N J, Maizels, R.M., McKenzie, A. N. J.   +15 more
core   +1 more source

Helminth-induced prostaglandin signaling and dietary shifts in PUFA metabolism promote colitis-associated cancer [PDF]

Oxylipins derived from dietary polyunsaturated fatty acids (PUFAs) are key determinants of intestinal health, homeostasis, and inflammatory disorders, such as colitis-associated colorectal cancer. Previous research has independently linked a high dietary
William Horsnell (21066185), Matthew G Darby (22249795), Awen Gallimore (50379), Claire Butters (12490086), Katherine A Smith (22249786), Valerie B O’Donnell (14757400), Alisha Chetty (2273359), Ella K Reed (22249789), Irina Guschina (542401), Victoria J Tyrrell (22249792), Brunette Katsandegwaza (760689)   +10 more
core   +3 more sources

Pharmacological and Therapeutic Potential of Garlic (Allium sativum): Integrating Phytochemistry, Molecular Mechanisms, and Clinical and Preclinical Evidence

ChemistryOpen, Volume 15, Issue 11, November 2026.
Garlic bioactive compounds, including organosulfur compounds (allicin, DADS, DATS, and SAC), phenolic compounds, and quercetin, regulate the Nrf2/HO‐1, NF‐κB, PI3K/Akt, and AMPK/eNOS signaling pathways. These actions enhance antioxidant defenses, suppress inflammation, improve metabolic and cardiovascular function, and contribute to reduced blood ...
Gudisa Bereda
wiley   +1 more source

Helminth infection in southern Laos: high prevalence and low awareness [PDF]

, 2013
BACKGROUND: Helminthiasis is a public health concern in Lao People’s Democratic Republic (Lao PDR, Laos). This study aimed to understand helminth infection and associated risk factors in relation to existing local knowledge, attitudes and practices ...
Xayaseng, Vilavanh, Akkhavong, Kongsap, Vonghachack, Youthanavanh, van Eeuwijk, Peter, Phongluxa, Khampheng, Odermatt, Peter, Peter van Eeuwijk, Khampheng Phongluxa, Xayaseng V, Vilavanh Xayaseng, van Eeuwijk P, Odermatt P, Youthanavanh Vonghachack, Peter Odermatt, Vonghachack Y, Akkhavong K, Kongsap Akkhavong, Phongluxa K   +17 more
core   +1 more source