Results 51 to 60 of about 557,652 (221)

Serotonin Degradation and Lipid Metabolism Regulate Human Tc2 Cell Effector Functions

Allergy, EarlyView.
Human Tc2 cells exhibit a metabolically active phenotype characterized by enhanced glycolysis, mitochondrial respiration, and fatty acid uptake dependent on PPARγ. Alarmins strongly amplify IL‐5 and IL‐13 production in Tc2 cells, supporting a shared immunometabolic program across type 2 lymphocytes.
Sabrina de Souza Ferreira, Lisa Holla, Sophia Björkander, Marie Kaarup Bek, Lorenz Wirth, Patrick A. Shearer, Jesper Säfholm, Erik Sachs, Mamdoh Al‐Ameri, Kasra Vali, Sandra Ekström, Erik Melén, Jenny Mjösberg, Christopher Andrew Tibbitt   +13 more
wiley   +1 more source

Associations between mild-to-moderate anaemia in pregnancy and helminth, malaria and HIV infection in Entebbe, Uganda. [PDF]

, 2007
It is suggested that helminths, particularly hookworm and schistosomiasis, may be important causes of anaemia in pregnancy. We assessed the associations between mild-to-moderate anaemia (haemoglobin >8.0 g/dl and
Nabulime, Juliet, Patrick Woodburn, Omoding, Nicholas, Kizito, D, Morison, LA, Muhangi, Lawrence, Lawrence Muhangi, Alison M. Elliott, Mildred Omara, Juliet Nabulime, Elliott, Alison M, Kizito, Dennison, Elliott, AM, Nicholas Omoding, Nabulime, J, Mpairwe, Harriet, Ameke, C, Woodburn, Patrick, Muhangi, L, Ameke, Christine, Ornoding, N, Mpairwe, H, Woodburn, P, Morison, Linda A, Dennison Kizito, Omara, M, Omara, Mildred, Christine Ameke, Harriet Mpairwe, Linda A. Morison   +29 more
core   +2 more sources

Low incidence of helminth infections (schistosomiasis, strongyloidiasis, filariasis, toxocariasis) among Dutch long-term travelers: A prospective study, 2008-2011.

PLoS ONE, 2018
BackgroundDespite the considerable burden of helminth infections in developing countries and increasing international travel, little is known about the risks of infection for travelers.ObjectiveWe studied the attack and incidence rate of serology ...
Femke W Overbosch, Tom van Gool, Amy Matser, Gerard J B Sonder   +3 more
doaj   +1 more source

Performance of a rapid immuno-chromatographic test (Schistosoma ICT IgG-IgM) for detecting Schistosoma-specific antibodies in sera of endemic and non-endemic populations.

PLoS Neglected Tropical Diseases, 2022
BackgroundSchistosomiasis, an acute and chronic parasitic disease caused by human pathogenic Schistosoma species, is a neglected tropical disease affecting more than 220 million people worldwide.
Julie Hoermann, Esther Kuenzli, Carmen Schaefer, Daniel H Paris, Silja Bühler, Peter Odermatt, Somphou Sayasone, Andreas Neumayr, Beatrice Nickel   +8 more
doaj   +1 more source

Basophils in Immunity: Activation Pathways, Roles in Allergy and AllergoOncology and Application of the Basophil Activation Test

Allergy, EarlyView.
ABSTRACT Basophils, the least abundant leukocytes, are increasingly recognised as potent immunomodulators. Upon activation, they rapidly release preformed granule‐associated mediators including histamine and lipid mediators such as LTC4, while cytokine production occurs over a longer timescale, contributing to downstream immune responses.
Jitesh Chauhan, Sofia Vlasova, Alicia Chenoweth, Debra H. Josephs, Heather J. Bax, Sophia N. Karagiannis   +5 more
wiley   +1 more source

MLL1 directs gut-associated antibody responses to helminth and bacterial infections

The Journal of Immunology
Abstract Soil-transmitted helminths are one of the most common infections globally, yet how to promote effective gut-associated humoral responses is not well understood. We identify the histone methyltransferase MLL1 as a key target to promote IgA-driven responses.
Yan Zhang, Clarissa Chakma, Alana Kirn, David Chisanga, Jack Polmear, Aidil Zaini, Rohia Farighi, Lennard Dalit, Liang Xie, Diana López-Ureña, Steven Mileto, Dena Lyras, Colby Zaph, Joanna R Groom, Kim L Good-Jacobson   +14 more
openaire   +3 more sources

IgE‐Binding Bacterial Components Not Yet Documented in the Allergen Databases and Their Allergenic Mechanisms: An EAACI Position Paper

Allergy, EarlyView.
ABSTRACT Among bacteria that are associated with the development and/or exacerbation of allergic/atopic diseases, several have been described to produce IgE‐binding components. However, only one bacterial protein, Bac s 1, is currently listed in the official database of the World Health Organization/International Union of Immunological Societies (WHO ...
Uta Jappe, Marua Abu Risha, Ioana Agache, Claus Bachert, Barbara Bröker, Riccardo Castagnoli, Gabriele Gadermaier, Richard E. Goodman, Amir Guemari, Christiane Hilger, Alain Jacquet, Sabine Kespohl, Ludger Klimek, Annette Kuehn, Jonas Lidholm, Vera Mahler, Markus Ollert, Thomas A. Platts‐Mills, Monika Raulf, Peter Schmid‐Grendelmeier, Frieder Schmiedeke, Marianne van Hage, Joana Vitte, Josefina Zakzuk, Anna Pomés   +24 more
wiley   +1 more source

Prevalence of Toxoplasma gondii antibodies and intestinal parasites in stray cats from Nigde, Turkey

Italian Journal of Animal Science, 2010
The prevalence of antibodies to Toxoplasma gondii was investigated by the Sabin-Feldman Dye test (SFDT) in 72 stray cats from Nigde, Turkey. A total of 55 (76.4%) of the analysed sera had antibodies to T. gondii. The seropositivity of T. gondii was 77.1%
Bengi Dündar, Selçuk Kiliç, Mustafa Karatepe, Cahit Babür, Bilge Karatepe   +4 more
doaj   +1 more source

Understanding the Type 2 Immunity: An Evolving View Beyond Allergic Diseases

Allergy, EarlyView.
ABSTRACT Type 2 (T2) immunity is classically associated with defense against helminths and environmental threats, from a physiological perspective, and with allergies and eosinophilic inflammatory diseases, in a pathological sense. However, growing evidence reveals that T2 pathways also support other essential homeostatic functions, including tissue ...
Rodrigo Jiménez‐Saiz, Salvador Iborra, Carlos Blanco, Ruperto González‐Pérez, Emilio Nuñez‐Borque, Can Zeyneloglu, Huseyn Babayev, Ozlem Göksel, Tuncay Göksel, Musa Khaitov, Dmitry Kudlay, Yadong Gao, Mustafa Sevim, Marie‐Charlotte Brüggen, Oral Alpan, Ming Wang, Luo Zhang, María J. Torres, Mohamed Shamji, Mübeccel Akdis, Kari C. Nadeau, Ismail Ogulur, Cezmi A. Akdis   +22 more
wiley   +1 more source

Eosinophils Control Liver Damage by Modulating Immune Responses Against Fasciola hepatica

Frontiers in Immunology, 2020
Eosinophils are granulocytes that participate in the defense against helminth parasites and in hypersensitivity reactions. More recently, eosinophils were shown to have other immunomodulatory functions, such as tissue reparation, metabolism regulation ...
Sofía Frigerio, Valeria da Costa, Monique Costa, María Florencia Festari, Mercedes Landeira, Santiago A. Rodríguez-Zraquia, Steffen Härtel, Jorge Toledo, Teresa Freire   +8 more
doaj   +1 more source