Results 41 to 50 of about 557,652 (221)

Immunological interactions between 2 common pathogens, Th1-inducing protozoan Toxoplasma gondii and the Th2-inducing helminth Fasciola hepatica.

PLoS ONE, 2009
BackgroundThe nature of the immune response to infection is dependent on the type of infecting organism. Intracellular organisms such as Toxoplasma gondii stimulate a Th1-driven response associated with production of IL-12, IFN-gamma, nitric oxide and ...
Catherine M D Miller, Nicholas C Smith, Rowan J Ikin, Nicola R Boulter, John P Dalton, Sheila Donnelly   +5 more
doaj   +1 more source

Concomitant influence of helminth infection and landscape on the distribution of Puumala hantavirus in its reservoir, Myodes glareolus

BMC Microbiology, 2011
Background Puumala virus, the agent of nephropathia epidemica (NE), is the most prevalent hantavirus in Europe. The risk for human infection seems to be strongly correlated with the prevalence of Puumala virus (PUUV) in populations of its reservoir host ...
Henttonen Heikki, Voutilainen Liina, Sironen Tarja, Poulle Marie-Lazarine, Cadet Patrice, Chaval Yannick, Xuéreb Anne, Guivier Emmanuel, Salvador Alexis, Cosson Jean-François, Charbonnel Nathalie   +10 more
doaj   +1 more source

Advancing pharmacometrics in Africa—Transition from capacity development toward job creation

CPT: Pharmacometrics &Systems Pharmacology, Volume 14, Issue 3, Page 407-419, March 2025.
Abstract Trained pharmacometricians remain scarce in Africa due to limited training opportunities, lack of a pharmaceutical product development ecosystem, and emigration to high‐income countries. The Applied Pharmacometrics Training (APT) fellowship program was established to address these gaps and specifically foster job creation for talent retention.
Goonaseelan (Colin) Pillai, Samer Mouksassi, Innocent G. Asiimwe, Craig R. Rayner, Steven Kern, Phumla Sinxadi, Paolo Denti, Eric Decloedt, Catriona Waitt, Bernhards R. Ogutu, Rik de Greef   +10 more
wiley   +1 more source

IgG Antibody responses in mice coinfected with Toxocara canis and other helminths or protozoan parasites [PDF]

Revista do Instituto de Medicina Tropical de São Paulo, 2012
The immune response expressed by IgG antibodies in BALB/c mice experimentally infected with Toxocara canis, was studied with the aim of verifying the possible in vivo cross-reactivity between antigens of T. canis and other parasites (Ascaris suum, Taenia crassiceps, Schistosoma mansoni, Strongyloides venezuelensis and Toxoplasma gondii).
Lescano, Susana A. Zevallos, Nakhle, Maria Cristina, Ribeiro, Manoel Carlos S.A., Chieffi, Pedro Paulo   +3 more
openaire   +5 more sources

Filariae-Retrovirus Co-infection in Mice is Associated with Suppressed Virus-Specific IgG Immune Response and Higher Viral Loads. [PDF]

PLoS Neglected Tropical Diseases, 2016
Worldwide more than 2 billion people are infected with helminths, predominantly in developing countries. Co-infections with viruses such as human immunodeficiency virus (HIV) are common due to the geographical overlap of these pathogens.
Kirsten Katrin Dietze, Ulf Dittmer, Daniel Karim Koudaimi, Simone Schimmer, Martina Reitz, Minka Breloer, Wiebke Hartmann   +6 more
doaj   +1 more source

Biology, ecology, and conservation of the Italian hare Lepus corsicanus: a review

Wildlife Biology, EarlyView.
The Italian hare Lepus corsicanus, an endemic lagomorph of Italy, serves as a critical case study in evolutionary biology and conservation. Once taxonomically debated, modern genetic and morphological analyses confirm its status as a distinct Pleistocene lineage restricted to the central‐southern Italian Peninsula and Sicily.
Pierangelo Freschi, Valter Trocchi
wiley   +1 more source

Ascaris lumbricoids Infection as a Risk Factor for Asthma and Atopy in Rural Bangladeshi Children. [PDF]

, 2014
Controversy persists as to whether helminth infections cause or protect against asthma and atopy. The aim of this study was to investigate the effects of helminth infection on asthma and atopy among Bangladeshi children.
Persson, Lars Å, Noguchi, Emiko,, Itoh, Makoto,, Noguchi, Emiko, Wagatsuma, Yukiko,, Raqib, Rubhana,, Wagatsuma, Yukiko, Ma, Enbo, Moore, Sophie E; id_orcid, Moore, Sophie E,, Moore, Sophie E, Persson, Lars-Åke,, Raqib, Rubhana, Hawlader, Mohammad D H, Hawlader, Mohammad D H,, Arifeen, Shams E,, Arifeen, Shams E, Ma, Enbo,, Itoh, Makoto, Hawlader, Mohammad DH   +19 more
core   +1 more source

Helminth exposure and immune response to the two-dose heterologous Ad26.ZEBOV, MVA-BN-Filo Ebola vaccine regimen.

PLoS Neglected Tropical Diseases
BackgroundThe exposure to parasites may influence the immune response to vaccines in endemic African countries. In this study, we aimed to assess the association between helminth exposure to the most prevalent parasitic infections, schistosomiasis, soil ...
Houreratou Barry, Edouard Lhomme, Mathieu Surénaud, Moumini Nouctara, Cynthia Robinson, Viki Bockstal, Innocent Valea, Serge Somda, Halidou Tinto, Nicolas Meda, Brian Greenwood, Rodolphe Thiébaut, Christine Lacabaratz   +12 more
doaj   +1 more source

Drivers of Host–Pathogen Community Assemblages in European Forests and Urban Green Spaces

Integrative Zoology, EarlyView.
ABSTRACT Despite advances in understanding infectious diseases, the persistence and re‐emergence of wildlife pathogens continue to raise public and veterinary health concerns. This study investigates the relationship between biodiversity and rodent‐borne diseases in Europe, focusing on habitat alterations and their impact on rodent diversity.
Vincent Sluydts, Marie Bouilloud, Maxime Galan, Hussein Alburkat, Anaïs Bordes, Vincent Bourret, Valeria Colombo, Luc DeBruyn, Lara Dutra, Jana Eccard, Jasmin Firozpoor, Romain Gallet, Maciej Grzybek, Heikki Henttonen, Jens Jacob, Andrew McManus, Tarja Sironen, Peter Stuart, Caroline Tatard, Benjamin Roche, Herwig Leirs, Nathalie Charbonnel   +21 more
wiley   +1 more source

Bayesian geostatistical modelling of soil-transmitted helminth survey data in the People's Republic of China [PDF]

, 2013
Soil-transmitted helminth infections affect tens of millions of individuals in the People's Republic of China (P.R. China). There is a need for high-resolution estimates of at-risk areas and number of people infected to enhance spatial targeting of ...
Zhou, Xiao-Nong, Lai, Ying-Si, Utzinger, Jürg, Ying-Si Lai, Xiao-Nong Zhou, Vounatsou, Penelope, Jürg Utzinger, Penelope Vounatsou, Lai YS, Zhou XN, Utzinger J, Vounatsou P   +11 more
core   +1 more source