Results 21 to 30 of about 12,131 (137)

Diagnostic Investigation of Two Cases of Oslerus osleri Infection in Dogs: Microscopic Challenges and Molecular Characterisation

Veterinary Medicine and Science, Volume 12, Issue 3, May 2026.
Two cases of young dogs with chronic cough were investigated, one with bronchoalveolar lavage for cytology, the other with endoscopic biopsy for histopathology. DNA was extracted from stained smears and from formalin paraffin‐embedded blocs, six primer pairs spanning the ribosomal RNA gene of O.
Jeremie Korchia, Vishnu Manikantan, Ashley K. McGrew, Christina M. Jeffries, Rebecca L. Makii, Kelly McCord, Sriveny Dangoudoubiyam   +6 more
wiley   +1 more source

Mixed Signals: T Cells as Architects of IgE Immunity

Immunological Reviews, Volume 339, Issue 1, May 2026.
ABSTRACT Food allergen‐specific IgE can cause significant pathology, yet the pathways that generate pathogenic, high‐affinity IgE remain incompletely understood. Increasing evidence suggests that IgE responses arise from the integration of multiple, and sometimes opposing, T cell–derived cues.
Abigail L. Tierney, Wallace P. Bezerra, Stephanie C. Eisenbarth, Adam Williams   +3 more
wiley   +1 more source

Prevalence of viral antibodies and helminths in field populations of house mice (Mus domesticus) in southeastern Australia [PDF]

Epidemiology and Infection, 1993
SUMMARYA 13-month study of wild mice (Mus domesticus) in wheatlands in southeastern Australia contrasted changes in the seroprevalence of antibody to 13 viruses and the occurrence of helminths with changes in their population dynamics. Mice were seropositive for mouse hepatitis virus (MHV), rotavirus, minute virus of mice (MVM), mouse adenovirus (MAdV),
G R, Singleton, A L, Smith, G R, Shellam, N, Fitzgerald, W J, Müller   +4 more
openaire   +2 more sources

Structural Determination of a Human IgE Epitope on Major Birch Allergen Bet v 1

Allergy, EarlyView.
Andrea O'Malley, Brooke T. Borders, Jeffrey M. Wilson, Scott A. Smith, Maksymilian Chruszcz   +4 more
wiley   +1 more source

Processing and release of endogenous immunogenic peptide signals

The Plant Journal, Volume 126, Issue 3, May 2026.
SUMMARY In both animals and plants, small secreted peptides known as cytokines and phytocytokines mediate local and systemic communication during immune and stress responses. These signaling molecules are typically synthesized as inactive precursors that require proteolytic processing to become active.
Maurice Koenig, Hermanyanto Laia, Gunther Doehlemann, Johana C. Misas Villamil   +3 more
wiley   +1 more source

Molecular Engineering of the Helminth TGF‐β Mimetics, TGM1 and TGM4, Reveals a Novel Antagonist of TGF‐β Signaling in Fibroblasts

The FASEB Journal, Volume 40, Issue 7, 15 April 2026.
The helminth TGF‐β mimic TGM4 activates SMAD signaling in macrophages and T cells through canonical TGF‐β receptors and the CD44 co‐receptor, through Domains 1–5 (D1‐5). In fibroblasts, which express lower levels of CD44, TGM4 binds but does not transduce a signal; furthermore, it inhibits activation by agonist ligands such as TGF‐β itself, in a manner
Kyle T. Cunningham, Claire Ciancia, Tiffany Campion, Maarten van Dinther, Nadia Davis, Anja Duffy, Anna L. L. Heawood, Luke Power, Anna Sanders, Shashi P. Singh, Danielle J. Smyth, Elizabeth Thompson, Ruby White, Andrew P. Hinck, Peter ten Dijke, Rick M. Maizels   +15 more
wiley   +1 more source

Why, Immunologically, Housing‐Related Fungi and Endotoxins (and Other Chronic Pro‐Inflammatory Stressors) Risk Latent Tuberculosis Reactivation, Severe Asthma, and Translocating and Invasive Infections in Indigenous Communities in Canada

American Journal of Human Biology, Volume 38, Issue 4, April 2026.
ABSTRACT Type 1/M1/TH1 and type 3/M1/TH17 pro‐inflammatory switches are risks for latent Mycobacterium tuberculosis (Mtb) reactivation and ongoing infection transmission. This paper considers the heavy toll of reactivation risk in Indigenous communities in Canada and the chronic, everyday pro‐inflammatory stressors connected with type 3/M1/TH17 immune ...
Stacie Burke
wiley   +1 more source

The role of T cells in sepsis of distinct infectious aetiologies

Clinical and Translational Discovery, Volume 6, Issue 2, April 2026.
Pathogen‐specific sepsis induces mitochondrial dysfunction in T cells, leading to functional alterations. Single‐cell transcriptomics reveals subtype‐specific impairments involving reactive oxygen species accumulation, mtDNA damage, calcium dysregulation, and metabolic reprogramming.
Xuanqi Liu, Bijun Zhu, Wanxin Duan, Ruixiang Kang, Xiangdong Wang, Liyang Li   +5 more
wiley   +1 more source

MLL1 directs gut-associated antibody responses to helminth and bacterial infections

The Journal of Immunology
Abstract Soil-transmitted helminths are one of the most common infections globally, yet how to promote effective gut-associated humoral responses is not well understood. We identify the histone methyltransferase MLL1 as a key target to promote IgA-driven responses.
Yan Zhang, Clarissa Chakma, Alana Kirn, David Chisanga, Jack Polmear, Aidil Zaini, Rohia Farighi, Liang Xie, Diana López-Ureña, Steven Mileto, Dena Lyras, Colby Zaph, Joanna R Groom, Kim L Good-Jacobson   +13 more
openaire   +2 more sources

Structural insights into glycan recognition by plant immune receptors: a comparative perspective with animal innate immune systems

The Plant Journal, Volume 126, Issue 1, April 2026.
SUMMARY Pattern recognition receptors (PRRs) function across diverse eukaryotic organisms as a powerful surveillance system to perceive danger signals and to trigger specific adaptive responses. This complex receptor network constitutes the first layer of perception of the innate immune system of plants and mammals.
Gonzalo Vílchez‐Pinto, María Garrido‐Arandia, Antonio Molina, Miguel Ángel Torres, Lucía Jordá   +4 more
wiley   +1 more source