Results 21 to 30 of about 557,652 (221)

Necator americanus and helminth co-infections: further down-modulation of hookworm-specific type 1 immune responses. [PDF]

, 2011
BACKGROUND: Helminth co-infection in humans is common in tropical regions of the world where transmission of soil-transmitted helminths such as Ascaris lumbricoides, Trichuris trichiura, and the hookworms Necator americanus and Ancylostoma duodenale as ...
Jeffrey Michael Bethony, Correa-Oliveira, Rodrigo, Geiger Stefan Michael, Brooker Simon, Brooker, Simon, Bonnie Cundill, Bethony Jeffrey Michael, Geiger, Stefan Michael, Cundill, Bonnie, Correa-Oliveira Rodrigo, Diemert David Joseph, Fujiwara, Ricardo Toshio, Cundill Bonnie, Neal Douglas Edward Alexander, David Joseph Diemert, Rodrigo Correa-Oliveira, Oliveira, Rodrigo Corrêa, Simon Brooker, Alexander Neal Douglas Edward, Alexander, Neal Douglas Edward, Bethony, Jeffrey Michael, Diemert, David Joseph, Fujiwara Ricardo Toshio, Stefan Michael Geiger, Ricardo Toshio Fujiwara   +24 more
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Modelling the geographical distribution of soil-transmitted helminth infections in Bolivia [PDF]

, 2013
The prevalence of infection with the three common soil-transmitted helminths (i.e. Ascaris lumbricoides, Trichuris trichiura, and hookworm) in Bolivia is among the highest in Latin America. However, the spatial distribution and burden of soil-transmitted
Utzinger, Jürg, Scholte, Ronaldo Gc, Chammartin, Frédérique, Bavia, Mara E., Vounatsou, Penelope, Malone, John B., Nieto, Prixia, Mara E Bavia, Malone JB, Ronaldo GC Scholte, Chammartin F, Frédérique Chammartin, Utzinger J, Nieto P, John B Malone, Penelope Vounatsou, Vounatsou P, Prixia Nieto, Bavia ME, Jürg Utzinger, Scholte RG   +20 more
core   +1 more source

Suppression of allergic airway inflammation by helminth-induced regulatory T cells [PDF]

, 2005
Allergic diseases mediated by T helper type (Th) 2 cell immune responses are rising dramatically in most developed countries. Exaggerated Th2 cell reactivity could result, for example, from diminished exposure to Th1 cell–inducing microbial infections ...
Lamb, Jonathan, Mark S. Wilson, Adam Balic, Constance A.M. Finney, Taylor, Matthew D, Finney, Constance A, Matthew D. Taylor, Rick M. Maizels, Maizels, Rick, Jonathan R. Lamb, Wilson, Mark A, Balic, Adam   +11 more
core   +1 more source

Antibody-Based Protective Immunity against Helminth Infections: Antibody Phage Display Derived Antibodies against BmR1 Antigen [PDF]

International Journal of Molecular Sciences, 2017
Helminth parasite infections are significantly impacting global health, with more than two billion infections worldwide with a high morbidity rate. The complex life cycle of the nematodes has made host immune response studies against these parasites extremely difficult.
Anizah Rahumatullah, Izzati Abdul Karim, Rahmah Noordin, Theam Lim   +3 more
openaire   +2 more sources

Exploring the immunology of parasitism--from surface antigens to the hygiene hypothesis [PDF]

, 2009
Helminth immunology is a field which has changed beyond recognition in the past 30 years, transformed not only by new technologies from cDNA cloning to flow cytometry, but also conceptually as our definition of host immune pathways has matured.
R. M. MAIZELS, Maizels, R M
core   +1 more source

The effect of current Schistosoma mansoni infection on the immunogenicity of a candidate TB vaccine, MVA85A, in BCG-vaccinated adolescents: An open-label trial. [PDF]

PLoS Neglected Tropical Diseases, 2017
Helminth infection may affect vaccine immunogenicity and efficacy. Adolescents, a target population for tuberculosis booster vaccines, often have a high helminth burden. We investigated effects of Schistosoma mansoni (Sm) on the immunogenicity and safety
Anne Wajja, Dennison Kizito, Beatrice Nassanga, Angela Nalwoga, Joyce Kabagenyi, Simon Kimuda, Ronald Galiwango, Gertrude Mutonyi, Samantha Vermaak, Iman Satti, Jaco Verweij, Edridah Tukahebwa, Stephen Cose, Jonathan Levin, Pontiano Kaleebu, Alison M Elliott, Helen McShane   +16 more
doaj   +1 more source

Expansion of Opportunistic Enteric Fungal Pathogens and Occurrence of Gut Inflammation in Human Liver Echinococcosis

Microbiology Spectrum, 2022
Increasing evidence shows that the gut fungal mycobiota is implicated in human disease. However, its relationship with chronic helminth infections, which cause immunosuppression and affect over 1 billion people worldwide, remains unexplored.
Yugui Wang, Aijiang Guo, Zhongli Liu, Yang Zou, Wenjun Zhu, Shile Wu, Shengying Zhang, Xiaola Guo, Shaohua Zhang, Lixia Pu, Xing-Quan Zhu, Guan Zhu, Xuepeng Cai, Shuai Wang   +13 more
doaj   +1 more source

Human helminth therapy to treat inflammatory disorders - where do we stand? [PDF]

, 2015
Parasitic helminths have evolved together with the mammalian immune system over many millennia and as such they have become remarkably efficient modulators in order to promote their own survival.
Helmby, Helena, Helena Helmby
core   +1 more source

Mucosal immune responses following intestinal nematode infection. [PDF]

, 2014
In most natural environments, the large majority of mammals harbour parasitic helminths that often live as adults within the intestine for prolonged periods (1-2 years).
Harris, N. L., P. J. Cooper, Zaph, C, Cooper, P. J., C. Zaph, Cooper, PJ, Harris, NL, Zaph, C., Cooper, Philip, N. L. Harris, Cooper, Philip John   +10 more
core   +1 more source

Antibody-Mediated Trapping of Helminth Larvae Requires CD11b and Fcγ Receptor I [PDF]

The Journal of Immunology, 2015
Abstract Infections with intestinal helminths severely impact on human and veterinary health, particularly through the damage that these large parasites inflict when migrating through host tissues. Host immunity often targets the motility of tissue-migrating helminth larvae, which ideally should be mimicked by anti-helminth vaccines ...
Bieren, Julia Esser-Von, Volpe, Beatrice, Kulagin, Manuel, Sutherland, Duncan B., Guiet, Romain, Seitz, Arne, Marsland, Benjamin J., Verbeek, J. Sjef, Harris, Nicola L.   +8 more
openaire   +4 more sources