ICOS controls Foxp3+ regulatory T-cell expansion, maintenance, and IL-10 production during helminth infection [PDF]
, 2012 Foxp3+ regulatory T (Treg) cells are key immune regulators during helminth infections, and identifying the mechanisms governing their induction is of principal importance for the design of treatments for helminth infections, allergies and autoimmunity ...
van der Werf, Nienke +22 more
core +1 more source
Toxoplasma Co-infection Prevents Th2 Differentiation and Leads to a Helminth-Specific Th1 Response
Frontiers in Cellular and Infection Microbiology, 2017 Nematode infections, in particular gastrointestinal nematodes, are widespread and co-infections with other parasites and pathogens are frequently encountered in humans and animals. To decipher the immunological effects of a widespread protozoan infection
Norus Ahmed +7 more
doaj +1 more source
Infection and co-infection with helminths and Plasmodium among school children in Côte d'Ivoire : results from a National Cross-Sectional Survey [PDF]
, 2014 Helminth infection and malaria remain major causes of ill-health in the tropics and subtropics. There are several shared risk factors (e.g., poverty), and hence, helminth infection and malaria overlap geographically and temporally.
Silué, Kigbafori D. +59 more
core +2 more sources
Superimposed visceral leishmanial infection aggravates response to Heligmosomoides polygyrus
Parasites & Vectors, 2018 Background Polyparasitism is the rule in all animal species, including humans, and has an important role in pathogenicity, diagnosis and control measures.
M. E. González-Sánchez +2 more
doaj +1 more source
Vaccines, 2020 Helminth parasites release extracellular vesicles which interact with the surrounding host tissues, mediating host–parasite communication and other fundamental processes of parasitism.
Gebeyaw G. Mekonnen +9 more
doaj +1 more source
Plasmodium-helminth coinfection and its sources of heterogeneity across East Africa. [PDF]
, 2012 BACKGROUND: Plasmodium-helminth coinfection can have a number of consequences for infected hosts, yet our knowledge of the epidemiology of coinfection across multiple settings is limited.
Pullan, Rachel L +6 more
core +1 more source
Human Schistosome Infection and Allergic Sensitisation [PDF]
, 2012 Several field studies have reported an inverse relationship between the prevalence of helminth infections and that of allergic sensitisation/atopy. Recent studies show that immune responses induced by helminth parasites are, to an extent, comparable to ...
Francisca Mutapi +5 more
core +1 more source
Harnessing helminth-driven immunoregulation in the search for novel therapeutic modalities.
PLoS Pathogens, 2020 Parasitic helminths have coevolved with humans over millennia, intricately refining and developing an array of mechanisms to suppress or skew the host's immune system, thereby promoting their long-term survival.
Stephanie M Ryan +4 more
doaj +1 more source
Network model of immune responses reveals key effectors to single and co-infection dynamics by a respiratory bacterium and a gastrointestinal helminth [PDF]
, 2012 Co-infections alter the host immune response but how the systemic and local processes at the site of infection interact is still unclear. The majority of studies on co-infections concentrate on one of the infecting species, an immune function or group of
Isabella M. Cattadori +21 more
core +2 more sources
Microbiome, 2021 Background Studies on the inhibition of inflammation by infection with helminth parasites have, until recently, overlooked a key determinant of health: the gut microbiota.
Adam Shute +9 more
doaj +1 more source