Results 191 to 200 of about 64,954 (254)

HUMAN MONOCLONAL ANTIBODIES

British Medical Bulletin, 1984
The technology for the production of murine monoclonal antibodies has been refined enormously since its introduction in 1975. However, the technology for generating human monoclonal antibodies has only recently come into its own. In this review, three currently available approaches to the production of human monoclonal antibodies are described.
S P, Cole, B G, Campling, T, Atlaw, D, Kozbor, J C, Roder   +4 more
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A human monoclonal antibody to insulin

Diabetes, 1986
To elucidate the immune aspects of insulin-dependent diabetes mellitus (IDDM), we attempted to generate human monoclonal anti-insulin antibodies by fusing peripheral blood lymphocytes obtained from 10 insulin-treated IDDM patients with cells from a human lymphoblastoid cell line. Hybridomas that secreted immunoglobulins appeared in 9 of 400 wells.
A, Livneh, H, Avraham, D, Elias, J, Sack, I R, Cohen, Z, Eshhar   +5 more
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Monoclonal antibodies to human casein

Molecular Immunology, 1985
Two monoclonal antibodies, LICR-LON-32.2 (32.2) and LICR-LON-14.1 (14.1), are described which react with human casein. 32.2 reacts with human beta-casein and 14.1 with human kappa-casein. 32.2 also reacts with rat band 2 casein and bovine beta-casein, but 14.1 appears to be specific for human kappa-casein. These monoclonal antibodies do not cross-react
H M, Earl, R A, McIlhinney
openaire   +2 more sources

Monoclonal antibodies to human amnion

Journal of Reproductive Immunology, 1986
Mouse hybridoma cell lines secreting monoclonal antibodies to human amnion were established. The reactivities of eight of these monoclonal antibodies (GB1, GB3, GB4, GB5, GB6, GB9, GB10 and GB11) on human skin and term extra-embryonic tissues, which included reflected amniochorions, basal plates, placentae, chorionic plates and umbilical cords, are ...
B L, Hsi, C J, Yeh
openaire   +2 more sources

Human and chimpanzee monoclonal antibodies

Journal of Immunological Methods, 1985
Monoclonal antibody-secreting cell lines were isolated after transformation of peripheral blood leukocytes with Epstein-Barr virus. Blood samples were obtained from human donors having circulating antibodies against hepatitis viruses (HAB, HBV), rubella, or rabies virus and from a chimpanzee infected with HAV. Dextran-isolated leukocytes were submitted
F C, Van Meel, P G, Steenbakkers, J C, Oomen   +2 more
openaire   +2 more sources