Results 211 to 220 of about 64,954 (254)
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A Human Monoclonal Antibody to rh^G
Vox Sanguinis, 1986Abstract. Hybridomas secreting a human monoclonal IgG1 antibody against a variant of the rhG antigen were produced from B lymphocytes of an Rh‐negative donor with serum antibodies to D and C antigens. The antibody reacts by indirect hemagglutination with nearly all C‐ or D‐positive cells, confirming the strong association in the expression of G with D
S K, Foung +4 more
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A Human Monoclonal Antibody Reactive with Human Prostate
Journal of Urology, 1984A human immunoglobulin M monoclonal antibody secreting hybridoma, termed MHG7, has been isolated and characterized for its reactivity against human prostate cells. Lymphocytes isolated from a regional draining lymph node of a patient with prostate carcinoma were fused with murine P3-NS1-Ag4-1 myeloma cells.
D H, Lowe +4 more
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Human monoclonal macroglobulins with antibody activity
Seminars in Oncology, 2003Assays for specific antigen-binding activity were performed on sera from 172 patients with monoclonal macroglobulinemia defined by immunofixation electrophoresis. The sera were collected between 1970 and 2002. Mean IgM level was 1,409 mg/dL with a range from 70 to 6,800.
Marvin J, Stone +5 more
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1985
The monoclonal antibody technology has had a major impact on the serological and biochemical analysis of human tumor antigens. Monoclonal antibodies have rapidly led to the identification and characterization of a large number of antigenic determinants on cancer cells.
Alan N. Houghton, Richard J. Cote
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The monoclonal antibody technology has had a major impact on the serological and biochemical analysis of human tumor antigens. Monoclonal antibodies have rapidly led to the identification and characterization of a large number of antigenic determinants on cancer cells.
Alan N. Houghton, Richard J. Cote
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Humanization of Monoclonal Antibodies
1994Antibodies of predefined specificity have many potential uses in human therapy and diagnosis, and hybridoma technology (Koehler and Milstein 1975) has made possible the generation of virtually limitless amounts of such antibodies. Unfortunately, hybridoma proteins are more easily obtained from nonhuman, usually rodent, sources and the use of those ...
G. E. Mark, E. A. Padlan
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MONOCLONAL ANTIBODIES TO HUMAN TRANSFERRINS
British Journal of Haematology, 1988A B, Mason, S A, Brown, R C, Penhallow
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Humanized Mice as a Tool to Study Sepsis—More Than Meets the Eye
International Journal of Molecular Sciences, 2021, Laudanski Krzysztof
exaly
The development and improvement of immunodeficient mice and humanized immune system mouse models
Frontiers in Immunology, 2022Shuzhen Liao +2 more
exaly