Results 301 to 310 of about 169,027 (313)

Production of Human Monoclonal Antibodies

1984
The need to obtain human monoclonal antibodies has not been overshadowed by the immense success of mouse monoclonal antibody technology. Human monoclonal antibodies will be less antigenic for human in vivo studies and therapy; they will be more likely to recognize antigenic subtleties not easily detected by xenogeneic antibodies, and they will have ...
Bradley J. Dyer, James W. Larrick, David W. Buck, Kenneth E. Truitt, George Senyk, Andrew Raubitschek, Jinjuan Wang   +6 more
openaire   +2 more sources

Fully Human Therapeutic Monoclonal Antibodies

Journal of Immunotherapy, 2006
Monoclonal antibody (mAb) therapy has been facilitated by a number of technologic advances over the past 30 years. Whereas hybridoma development of murine mAbs was requisite for the development of mAbs as drugs, the inherent immunogenicity of rodent sequences in humans has presented obstacles to the clinical application of mAbs.
openaire   +3 more sources

Human monoclonal antibodies

Nature, 1982
A. Munro Neville, Karol Sikora
openaire   +2 more sources

Toward Human Monoclonal Antibodies

1990
OKT3 is a murine monoclonal antibody directed against an epitope on one of the subunits of the CD3 complex on human T cells. CD3 is associated with the T cell receptor and seems to play a role in the expression of the receptor. Clinically it is used as rescue treatment in renal allograft rejection and is currently being tested for use prophylactically ...
Dennis R. Burton, Edward S. Golub, Mats A. A. Persson, William D. Huse   +3 more
openaire   +2 more sources

Monoclonal antibodies in human reproduction

1984
This workshop centred on the effect which monoclonal antibodies (mAbs) are now beginning to make in various fields of research in human reproduction. An introduction by the chairperson, L. Mettler (Kiel, W. Germany), outlined the background to much of the technology involved in the production of mAbs based from the original work of Kohler and Milstein ...
P. M. Johnson, K. Hannon, L. Mettler
openaire   +2 more sources

MONOCLONAL ANTIBODIES TO HUMAN TRANSFERRINS

British Journal of Haematology, 1988
Anne B. Mason, Robert C. Penhallow, Stephen Brown   +2 more
openaire   +3 more sources

Monoclonal antibody to human fibronectin

Cell Biology International Reports, 1980
Walsh, F S, Dhut, S
openaire   +2 more sources

Humanized Monoclonal Antibodies

2006
Joel B. Cornacoff, Jill Giles-Komar
openaire   +1 more source

Monoclonal antibodies and human disease

Human Pathology, 1981
openaire   +3 more sources

Monoclonal antibodies to human trophoblast

Placenta, 1992
Peter M. Johnson, Bae-Li Hsi
openaire   +2 more sources