Results 161 to 170 of about 245,259 (243)

Evaluation of multi-antigen targeting ADCC strategies in pediatric BCP-ALL. [PDF]

J Immunother Cancer
Grain A, Ollier J, Le Calvez B, Guiet E, Thomas C, Couec ML, Camuset M, Rialland F, Eveillard M, Scotet E, Clémenceau B.   +10 more
europepmc   +1 more source

Engineering Tertiary Lymphoid Structures: Nanomedicine, Bioengineering, and Biomaterials for Precision Immunotherapy

Advanced NanoBiomed Research, EarlyView.
This review explains how biomaterials and nanoparticles can be used to induce or modulate tertiary lymphoid structures (TLSs), which are ectopic immune hubs that form in nonlymphoid tissues during chronic disease and cancer. By comparing different methods, the article highlights design principles for modeling TLSs or recapitulating specific TLS ...
Shaza Karaman, Mei ElGindi, Jeremy Teo
wiley   +1 more source

Development of predictable and high-yield CHO cell line by site-specific integration. [PDF]

J Biol Eng
Lan W, Yang X, Yao J, Lin LJ, Li W, Chen W, Li J, Shen Q, Li K, Li H, Chen Y, Chen L, Leung K.   +12 more
europepmc   +1 more source

Decoding the Pathophysiology of Autoimmune Diseases—Mechanism, Triggers, and Nanotherapeutics: A Review

Advanced NanoBiomed Research, EarlyView.
This review highlights how autoimmune diseases arise from intertwined immunological, genetic, and environmental factors, emphasizing gut microbiota dysbiosis as a pivotal driver. It outlines emerging nanotechnology‐based strategies—such as liposomes, hydrogels, and polymeric nanoparticles—that enhance targeted drug delivery, minimize systemic toxicity,
Md. Meraj Ansari, Yunhui Min, Eun‐Ju Ko, Doyoung Kwon, Rehan Khan, Young‐Ok Son   +5 more
wiley   +1 more source

Fab Antibody Fragments to Dog Leukocyte Antigen DR (DLA-DR) Directly Suppress Canine Lymphoma Cell Line Growth In Vitro and in Murine Xenotransplant Model. [PDF]

Cancers (Basel)
Studzińska A, Pieczka M, Kruszyńska A, Moniakowski L, Urbaniak A, Rapak A, Miazek A.   +6 more
europepmc   +1 more source

Immunomodulatory biomaterials for treating chronic inflammation at mucosal sites. [PDF]

NPJ Biomed Innov
Babb LM, Kulapurathazhe MJ, Collier JH.
europepmc   +1 more source

Monoclonal antibodies against the Crohn´s disease - involved pancreatic autoantigen [PDF]

, 1988
Horbach, E., Otte, M., Poschmann, A., Schwarting, K., Scriba, Peter Christian, Stöcker, W.   +5 more
core   +1 more source

Cytokine pathways driving diverse tissue pathologies in rheumatoid arthritis

Arthritis &Rheumatology, Accepted Article.
Rheumatoid arthritis is a complex systemic disorder characterised primarily by articular inflammation and destruction with associated functional loss and reduced quality of life. RA is also associated with extra‐articular disease e.g. of the lung with potentially devastating clinical consequences.
Aurelie Najm, Lyn D. Ferguson, Iain B. McInnes   +2 more
wiley   +1 more source

Preclinical characterisation of the protective capacity of an anti-nucleoprotein hRSV monoclonal antibody. [PDF]

EBioMedicine
Farías MA, Andrade CA, Loaiza RA, Rodríguez-Guilarte L, Muñoz JT, Pereira-Sánchez P, Muñoz-Durango N, Pizarro-Ortega MS, Diethelm-Varela B, Pereira-Serrano A, Ramírez RA, Chávez JL, Bohmwald K, Soto JA, González PA, Bueno SM, Kalergis AM.   +16 more
europepmc   +1 more source

Distinct HLA Associations for Antibody Multireactivity With Citrulline‐Containing Type II Collagen Epitopes Versus More Limited Antibody Reactivity With Citrulline‐Containing IgG Epitopes in Rheumatoid Arthritis

Arthritis &Rheumatology, EarlyView.
Objective Anticitrullinated protein antibodies (ACPAs) in rheumatoid arthritis (RA) can be promiscuous, with cross‐reactive binding to many antigens containing short motifs, or private with little cross‐reactivity. Also, ACPA reactivity patterns differ among patients with RA, including for motif‐containing epitopes in important self‐antigens like ...
S. Janna Bashar, Courtney B. Myhr, Adam H. Titi, Zihao Zheng, Miriam A. Shelef   +4 more
wiley   +1 more source