Results 181 to 190 of about 136,268 (220)

Engineered hematopoietic stem cells give rise to therapeutic antibody secreting B cells

Porteus M, Luna S, Feist W, Utz A, Afaghani J, Miyauchi M, Ghanim H, Ekman F, Amaya A, Selvaraj S, Russkamp N, Schmiderer L.   +11 more
europepmc   +1 more source

DLK1: a novel therapeutic target in cancer. [PDF]

Endocr Relat Cancer
Pittaway JFH.
europepmc   +1 more source

In Utero HSC Transplantation for Sickle Cell Disease: A Potential Therapeutic Approach That Overcomes Complications of Current Therapies

Prenatal Diagnosis, EarlyView.
ABSTRACT Sickle cell disease (SCD) affects millions worldwide but has limited treatment options, most of which carry significant side effects. At present, the only curative treatment for SCD is allogeneic or gene‐modified autologous hematopoietic stem cell (HSC) transplantation (Tx).
Oluwaseun O. Babatunde, Madeleine G. Bibby, Anthony Atala, Graça Almeida‐Porada, Christopher D. Porada   +4 more
wiley   +1 more source

Evaluation of multi-antigen targeting ADCC strategies in pediatric BCP-ALL. [PDF]

J Immunother Cancer
Grain A, Ollier J, Le Calvez B, Guiet E, Thomas C, Couec ML, Camuset M, Rialland F, Eveillard M, Scotet E, Clémenceau B.   +10 more
europepmc   +1 more source

Baicalein Sensitizes Radioresistant BT549 and MCF7‐R Breast Cancer Cells by Modulating Rac1 Signaling

Phytotherapy Research, EarlyView.
ABSTRACT Radioresistance remains a key barrier in breast cancer (BC) treatment. Baicalein, a flavonoid from Scutellaria baicalensis, has shown potential to enhance radiosensitivity. This study investigates its efficacy and mechanism in radioresistant BC models. Radioresistant BC cell models were established via fractionated irradiation and validated by
Zitong Zhao, Zhangyun Li, Quanzhou Peng, Shuqun Zhang   +3 more
wiley   +1 more source

The clinical value of multimodal neuroimaging in monoclonal antibody therapy for Alzheimer's disease. [PDF]

Front Neurol
Wang Y, Li H, Zhou J, Zhao S, Yang A, Li Z.   +5 more
europepmc   +1 more source

Functional Repurposing of Magnetic Nanoparticle‐Assisted Hyperthermia for Immune Cell Labelling and Tracking

Small Methods, EarlyView.
We propose mild‐MHT protocol for the quick internalization of magnetic nanoparticles (MNPs) by immune cells. The heat induced by MNPs under alternating magnetic field stimulate MNPs diffusion and cell membrane invagination, accelerating the cellular internalization of MNPs. ABSTRACT Immune cell therapies show promise in hematologic malignancies and are
Giulia E. P. Nucci, Chiara Vitale, Alessandro di Girolamo, Niccolò Silvestri, Stefano Persano, Lorenci Gjurgjaj, Cristina Bottino, Roberta Castriconi, Teresa Pellegrino   +8 more
wiley   +1 more source

The landscape of antibody production systems: recombinant expression for research, diagnostics and therapy. [PDF]

Front Bioeng Biotechnol
Wenzel EV, Al-Halabi-Frenzel L, Demiral S, Frenzel A, Gnann DC, Keitel MC, Lehmler N, Mukherjee T, Rauls J, Schirrmann T, Stańczyk PG, Steinke S, Terbrack J, Westerhoff S, Dübel S, Schubert M, Hust M, Bertoglio F.   +17 more
europepmc   +1 more source

Nonthermal plasma approaches for combating implant‐associated infections: A compendious review

VIEW, EarlyView.
Implant‐associated infections pose serious clinical challenges. Non‐thermal plasma (NTP) modifications overcome this bottleneck in distinct ways relative to traditional sterilization methods. Gas‐phase plasmas generate highly energetic species, UV radiation and reactive oxygen/nitrogen species (RONS), which alter the implant surface properties.
A. M. Trimukhe, Satish Rojekar, Amol Gholap, K. Navaneetha Pandiyaraj, Mukesh Patekar, Claudia Riccardi, R. R. Deshmukh, Tomáš Kovářík, Kalim Deshmukh   +8 more
wiley   +1 more source

Low-affinity binding of anti-B7-H3 clone MJ18 to murine B7-H3 fails to induce tumor regression. [PDF]

Sci Rep
Gulyás D, Nammor T, Frizzell JK, Lavoie RR, Geng L, Markovic SN, Lucien F.   +6 more
europepmc   +1 more source