Results 191 to 200 of about 236,432 (265)

Anti-cancer immune priming with β-radioligand therapy using a novel high affinity antibody selectively targeting the 4Ig-Isoform of B7-H3. [PDF]

Theranostics
Glazer SE, Sutton MN, Yang P, Pisaneschi F, Sebastian M, Gammon ST, Piwnica-Worms D.   +6 more
europepmc   +1 more source

Triggering Receptor Expressed on Myeloid Cells‐2 Regulates Innate Lymphoid Cell Levels in Bleomycin‐Induced Pulmonary Fibrosis

The Kaohsiung Journal of Medical Sciences, EarlyView.
ABSTRACT Idiopathic pulmonary fibrosis, a pathological change causing poor outcomes, is not reversible despite current antifibrotic therapy. Emerging evidence suggests that innate lymphoid cells (ILCs) mediate lung inflammation and fibrosis after stimulation by endogenous factors.
Hsiao‐Chin Shen, Nien‐Jung Chen, Chuan‐Yen Sun, Wen‐Kuang Yu, Vincent Yi‐Fong Su, Wan‐Ling Yang, Wei‐Chih Chen, Kuang‐Yao Yang   +7 more
wiley   +1 more source

Limited expression of B-cell maturation antigen in acute myeloid leukemia. [PDF]

J Immunother Cancer
Ran Y, Cheng W, Yi X, Yang S, Zhang W, Xu J.   +5 more
europepmc   +1 more source

Topological analysis of the human lymph node reticular network predicts outcome in breast cancer

The Journal of Pathology, EarlyView.
Abstract Axillary LNs (ALNs) initiate immune responses in breast cancer (BC) but how and when ALNs become dysfunctional, facilitating metastasis, is unclear. The fibroblastic reticular cell (FRC) network within ALNs provides structural support and mediates immune homeostasis, but we have yet to elucidate whether this network changes during BC ...
Amy M Llewellyn, Sharon L D'Costa, Cheun YR Lam, Jasmine A Gore, Veronika Lachina, Daniel J Shewring, Sophie E Acton, Kalnisha Naidoo   +7 more
wiley   +1 more source

MtrE Loop2-specific multiple antigenic peptide vaccine and monoclonal antibody confer complement-dependent protection against Neisseria gonorrhoeae. [PDF]

NPJ Vaccines
Song S, Ge H, Yuan D, Gu X, Lu W, Ding C, Qin Y, Gao S, Lin X, Cheng H, van der Veen S.   +10 more
europepmc   +1 more source

In Utero HSC Transplantation for Sickle Cell Disease: A Potential Therapeutic Approach That Overcomes Complications of Current Therapies

Prenatal Diagnosis, EarlyView.
ABSTRACT Sickle cell disease (SCD) affects millions worldwide but has limited treatment options, most of which carry significant side effects. At present, the only curative treatment for SCD is allogeneic or gene‐modified autologous hematopoietic stem cell (HSC) transplantation (Tx).
Oluwaseun O. Babatunde, Madeleine G. Bibby, Anthony Atala, Graça Almeida‐Porada, Christopher D. Porada   +4 more
wiley   +1 more source

LILRB4 shapes an immunosuppressive microenvironment to drive cervical cancer progression through tumor-infiltrating myeloid cell expansion and CD8⁺ T-cell suppression. [PDF]

Cell Mol Life Sci
Zhang Y, Gao Y, Guan X, Wang E, Tong R.
europepmc   +1 more source

Bioinformatics‐Driven Design and Evaluation of Recombinant Multi‐Epitope Immunogens Derived From Snake Venom Toxins as Potential Antivenom Candidates

Proteins: Structure, Function, and Bioinformatics, EarlyView.
ABSTRACT Snakebite envenomation is a major public health concern, particularly in low‐ and middle‐income regions where access to safe and effective antivenoms is limited. Traditional antivenoms, derived from immunization with crude venom, often trigger adverse reactions and lack specificity against key venom components.
Hanan Maoz, Amir Elalouf
wiley   +1 more source

Semaphorins: from CD8⁺ T cells to cancer immunotherapy. [PDF]

Biomark Res
Liu Z, Wu Y, Xu P, Xu H, Yin K, Wang S.
europepmc   +1 more source

Generation of virus specific cytotoxic T cells in vitro [PDF]

, 1979
Greber, D., Koszinowski, Ulrich H., Neuschaefer-Rube, I.   +2 more
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