Results 181 to 190 of about 180,168 (218)

Perspectives on the neutralization of interferons by antibody

Neurology, 2003
Interferon (IFN) neutralizing antibody (NAb) interferes with the binding of the IFN molecule to its cellular receptor, thereby preventing receptor activation required to trigger the cascade of signal transduction events that lead to the varied actions of IFN.
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Testing for neutralizing antibodies

British Journal of Neuroscience Nursing, 2007
Interferon-beta drugs for multiple sclerosis sometimes give rise to immune proteins that neutralize their effects. Nicola O'Connell and Bronwen Roper look at testing for these neutralizing antibodies
Nicola O'Connell, Bronwen Roper
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Interferon-β antibodies have a higher affinity in patients with neutralizing antibodies compared to patients with non-neutralizing antibodies

Journal of Neuroimmunology, 2006
In this study, we investigated the affinity, determined by a relative affinity assay, using increasing concentrations of sodium-isothiocyanate to disrupt the antigen antibody binding of neutralizing and non-neutralizing antibodies against interferon-beta (IFNbeta)-1a and -1b in 73 serum samples of MS patients treated with IFNbeta-1a or -1b.
C, Gneiss, P, Tripp, R, Ehling, M, Khalil, A, Lutterotti, R, Egg, I, Mayringer, B, Künz, T, Berger, M, Reindl, F, Deisenhammer   +10 more
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Antibody neutralization and escape by HIV-1

Nature, 2003
Neutralizing antibodies (Nab) are a principal component of an effective human immune response to many pathogens, yet their role in HIV-1 infection is unclear. To gain a better understanding of this role, we examined plasma from patients with acute HIV infection.
Xiping, Wei, Julie M, Decker, Shuyi, Wang, Huxiong, Hui, John C, Kappes, Xiaoyun, Wu, Jesus F, Salazar-Gonzalez, Maria G, Salazar, J Michael, Kilby, Michael S, Saag, Natalia L, Komarova, Martin A, Nowak, Beatrice H, Hahn, Peter D, Kwong, George M, Shaw   +14 more
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The influence of complement on cytomegalovirus neutralization by antibodies

Archiv f�r die gesamte Virusforschung, 1972
The influence of complement on the neutralization of cytomegalovirus by antibodies has been studied using human sera and antisera prepared in rabbits with various strains of cytomegalovirus (Ad 169, C 87, Davis andT 27). Examination of patient sera showed that addition of 2 per cent complement had only a weak and non-significant enhancing effect on ...
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Neutralization by Fragments of Antibody

1993
Experiments to determine whether or not the whole antibody molecule is necessary for neutralization were made possible by digestion with the proteolytic enzymes pepsin, which releases the Fc region leaving an F(ab)2 structure, or papain, which results in a monovalent antigen-binding fragment (Fab). Most data relate to IgG.
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Neutralization of interferon by specific antibody

Virology, 1962
K, PAUCKER, K, CANTELL
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mRNA-based COVID-19 vaccine boosters induce neutralizing immunity against SARS-CoV-2 Omicron variant

Cell, 2022
Evan C Lam, Maegan L Sheehan, Cristhian Berrios   +2 more
exaly  

COVID-19-neutralizing antibodies predict disease severity and survival

Cell, 2021
Wilfredo F Garcia-Beltran, Evan C Lam, Diane Yang   +2 more
exaly  

In vitro and in vivo functions of SARS-CoV-2 infection-enhancing and neutralizing antibodies

Cell, 2021
Dapeng Li, Robert J Edwards, Kartik Manne   +2 more
exaly