Results 161 to 170 of about 180,168 (218)
Protective Human Papillomavirus Type 16/18 Vaccine-Induced Neutralizing Antibody Levels Remain Elusive. [PDF]
Lehtinen M +11 more
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Evaluation of candidate reference materials for the harmonization of Lassa fever serology. [PDF]
Bentley EM +22 more
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Contemporary HIV-1 envelope pseudovirus panels for detecting and assessing B cell lineages with broadly neutralizing antibody potential. [PDF]
Korber B +15 more
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Recent advances in HIV-1 envelope-based vaccine designs for guiding broadly neutralizing antibody response. [PDF]
Singh S, Kumar S, Luthra K.
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Broadly Neutralizing Antiviral Antibodies
Annual Review of Immunology, 2013A fascinating aspect of viral evolution relates to the ability of viruses to escape the adaptive immune response. The widely held view has been that the great variability of viral glycoproteins would be an absolute obstacle to the development of antibody-based therapies or vaccines that could confer broad and long-lasting protection.
Corti D., Lanzavecchia A.
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Production of Neutralizing Antibody
2018Techniques employing monoclonal antibodies (mAbs) are widely used in the initial development phase of biologics. The usefulness of mAbs in basic RA research has been established based on their characteristics, including specificity of binding, homogeneity, and ability to be produced on a large scale.
Erika, Takemasa +2 more
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Neutralization of HIV by Antibodies
2008Antibodies can neutralize HIV-1 with potency and cross-reactivity that varies widely and is related but not correlated to their antigen-binding affinity. Therefore, in addition to measuring binding affinity, an evaluation of the antibody neutralizing activity in tissue cultures is important for development of antibody-based therapeutics, design of ...
Ilia, Prado +2 more
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The secretion of virus-neutralizing antibodies
Archiv f�r die gesamte Virusforschung, 1967Considerable evidence supports the concept that the immune defense against infectious agents that attack primarily the cells of the mucosal linings lies in secreted antibodies belonging to the IgA class of immunoglobulins. The problem that thus arises, in connection with the possible use of adjuvants in active immunization against these infectious ...
A, Giovanardi +4 more
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