Results 21 to 30 of about 1,849,608 (371)

Dissecting the human serum antibody response to secondary dengue virus infections. [PDF]

PLoS Neglected Tropical Diseases, 2017
Dengue viruses (DENVs) are mosquito-borne flaviviruses and the causative agents of dengue fever and dengue hemorrhagic fever. As there are four serotypes of DENV (DENV1-4), people can be infected multiple times, each time with a new serotype.
Bhumi Patel, Patti Longo, Michael J Miley, Magelda Montoya, Eva Harris, Aravinda M de Silva   +5 more
doaj   +1 more source

Neutralizing monoclonal antibodies for treatment of COVID-19

Nature reviews. Immunology, 2021
Several neutralizing monoclonal antibodies (mAbs) to severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) have been developed and are now under evaluation in clinical trials.
P. Taylor, A. Adams, M. Hufford, I. de la Torre, K. Winthrop, R. Gottlieb   +5 more
semanticscholar   +1 more source

Higher levels of neutralizing antibodies against KSHV in KS patients compared to asymptomatic individuals from Zambia. [PDF]

PLoS ONE, 2013
Kaposi sarcoma-associated herpesvirus (KSHV) is the etiologic agent for Kaposi Sarcoma (KS), the most common cancer diagnosed in HIV- infected patients.
Pankaj Kumar, Nithal Y Kuwa, Veenu Minhas, Clemence Marimo, Danielle M Shea, Chipepo Kankasa, Charles Wood   +6 more
doaj   +1 more source

Outliers Matter—Correlation between S1 IgG SARS-CoV-2 Antibodies and Neutralizing SARS-CoV-2 Antibodies

Microorganisms, 2022
Vaccination against the SARS-CoV-2 virus or infection with SARS-CoV-2 will lead to the development of IgG antibodies against the S1 protein of the SARS-CoV-2 virus.
Berthold Hocher, Anne Schönbrunn, Xin Chen, Bernhard K. Krämer, Volker von Baehr   +4 more
doaj   +1 more source

Isolation of potent SARS-CoV-2 neutralizing antibodies and protection from disease in a small animal model

Science, 2020
Protective neutralizing antibodies Antibodies produced by survivors of coronavirus disease 2019 (COVID-19) may be leveraged to develop therapies. A first step is identifying neutralizing antibodies, which confer strong protection against severe acute ...
T. Rogers, Fangzhu Zhao, Deli Huang, N. Beutler, Alison Burns, Wan-ting He, Oliver Limbo, C. Smith, G. Song, J. Woehl, Linlin Yang, R. Abbott, Sean Callaghan, Elijah Garcia, Jonathan Hurtado, M. Parren, Linghang Peng, S. Ramirez, James Ricketts, M. Ricciardi, Stephen A. Rawlings, N. Wu, M. Yuan, Davey M. Smith, D. Nemazee, J. Teijaro, J. Voss, I. Wilson, R. Andrabi, Bryan S. Briney, E. Landais, D. Sok, J. Jardine, D. Burton   +33 more
semanticscholar   +1 more source

Low levels of monkeypox virus-neutralizing antibodies after MVA-BN vaccination in healthy individuals

Nature Network Boston, 2022
In July 2022, the ongoing monkeypox (MPX) outbreak was declared a public health emergency of international concern. Modified vaccinia Ankara—Bavarian Nordic (MVA-BN, also known as Imvamune, JYNNEOS or Imvanex) is a third-generation smallpox vaccine that ...
Luca M. Zaeck, M. Lamers, B. Verstrepen, T. Bestebroer, M. V. van Royen, H. Götz, M. Shamier, L. V. van Leeuwen, K. Schmitz, Kimberley Alblas, Suzanne van Efferen, S. Bogers, S. Scherbeijn, G. Rimmelzwaan, E. V. van Gorp, M. Koopmans, B. Haagmans, C. Geurtsvankessel, R. D. de Vries   +18 more
semanticscholar   +1 more source

Broadly neutralizing antibodies target the coronavirus fusion peptide

bioRxiv, 2022
The potential for future coronavirus outbreaks highlights the need to develop strategies and tools to broadly target this group of pathogens. Here, using an epitope-agnostic approach, we identified six monoclonal antibodies that bound to spike proteins ...
Cherrelle Dacon, C. Tucker, Linghang Peng, C. D. Lee, Ting-Hui Lin, M. Yuan, Yu Cong, Lingshu Wang, Lauren Purser, Jazmean K. Williams, C. Pyo, I. Košík, Zhe Hu, Ming Zhao, Divya Mohan, Andrew J. R. Cooper, M. Peterson, J. Skinner, S. Dixit, Erin Kollins, Louis Huzella, Donna L. Perry, R. Byrum, Sanae Lembirik, Yi Zhang, E. Yang, Man Chen, K. Leung, R. Weinberg, A. Pegu, D. Geraghty, E. Davidson, I. Douagi, S. Moir, J. Yewdell, C. Schmaljohn, Peter D. Crompton, M. Holbrook, D. Nemazee, J. Mascola, I. Wilson, Joshua Tan   +41 more
semanticscholar   +1 more source

HIV-1 Env Does Not Enable the Development of Protective Broadly Neutralizing Antibodies in an Experimental Autoimmune Encephalomyelitis Mouse Model

Frontiers in Immunology, 2021
Recent studies showed that immunological tolerance may restrict the development of Env-specific autoreactive broadly neutralizing antibodies. This evidence is consistent with the finding that Env immunization of a systemic lupus erythematosus (SLE ...
Gabriel Siracusano, Annamaria Finardi, Claudia Pastori, Vittorio Martinelli, Roberto Furlan, Lucia Lopalco   +5 more
doaj   +1 more source

mRNA-1273 vaccine induces neutralizing antibodies against spike mutants from global SARS-CoV-2 variants

bioRxiv, 2021
Severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) is the causative infection of a global pandemic that has led to more than 2 million deaths worldwide.
Kai Wu, Anne P. Werner, Juan I. Moliva, M. Koch, A. Choi, Guillaume B. E. Stewart-Jones, H. Bennett, Seyhan Boyoglu-Barnum, W. Shi, B. Graham, A. Carfi, Kizzmekia S. Corbett, R. Seder, D. Edwards   +13 more
semanticscholar   +1 more source

mRNA vaccination boosts cross-variant neutralizing antibodies elicited by SARS-CoV-2 infection

Science, 2021
Boosterism could save lives Postinfection immune protection against severe acute respiratory syndrome coronavirus 2 reinfection is not fully understood.
L. Stamatatos, Julie L. Czartoski, Yu-Hsin Wan, Leah J. Homad, Vanessa Rubin, Hayley Glantz, M. Neradilek, Emilie Seydoux, Madeleine F. Jennewein, Anna J. MacCamy, Junli Feng, G. Mize, S. D. De Rosa, A. Finzi, Maria P. Lemos, Kristen W. Cohen, Z. Moodie, M. McElrath, A. McGuire   +18 more
semanticscholar   +1 more source