Monoclonal Antibodies for Protozoan Infections: A Future Reality or a Utopic Idea? [PDF]
Frontiers in Medicine, 2021 Following the SARS-CoV-2 pandemic, several clinical trials have been approved for the investigation of the possible use of mAbs, supporting the potential of this technology as a therapeutic approach for infectious diseases. The first monoclonal antibody (
Silvia Stefania Longoni +4 more
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Seroprevalence rates of antibodies againstLeishmania infantum and other protozoan and rickettsial parasites in dogs [PDF]
Revista Brasileira de Parasitologia Veterinária, 2013 Canine visceral leishmaniasis (CVL) is caused by the protozoan Leishmania infantum, which infects dogs and humans in many regions of Brazil. The present study involved an indirect fluorescent antibody test (IFAT) to analyze L.
Silvana de Cássia Paulan +7 more
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B-Cell Response during Protozoan Parasite Infections [PDF]
Journal of Parasitology Research, 2012 In this review, we discuss how protozoan parasites alter immature and mature B cell compartment. B1 and marginal zone (MZ) B cells, considered innate like B cells, are activated during protozoan parasite infections, and they generate short lived plasma ...
María C. Amezcua Vesely +4 more
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Seroprevalence of Toxoplasmosis Antibodies among Diabetes Mellitus Patients and Assessment some Biochemical Markers [PDF]
Ibn Al-Haitham Journal for Pure and Applied Sciences, 2018 Toxoplasma gondii is an protozoan intracellular coccidian protozoan parasite. Latent toxoplasmosis threat to immunocompetent individuals. Diabetic patients are more susceptible to infect with toxoplasmosis due to their low level of immunity ...
Sarah Ali Saeed, Israa Kasim Al-Aubaidi
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Monoclonal Antibodies to Intracellular Stages of
mSphere, 2018 Among the obstacles hindering Cryptosporidium research is the lack of an in vitro culture system that supports complete life development and propagation.
Georgia Wilke +9 more
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Veterinary Medicine and ScienceBackground Toxoplasma gondii is a zoonotic protozoan parasite of significant concern in both public and animal health. Objectives This study investigated the occurrence of T.
Phirom Prompiram +4 more
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Effect of biannual azithromycin distribution on antibody responses to malaria, bacterial, and protozoan pathogens in Niger [PDF]
Nature Communications, 2022 Abstract The MORDOR trial in Niger, Malawi, and Tanzania found that biannual mass distribution of azithromycin to children younger than 5 years led to a 13.5% reduction in all-cause mortality (NCT02048007). To help elucidate the mechanism for mortality reduction, we report IgG responses to 11 malaria, bacterial ...
Ahmed M. Arzika +15 more
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Use of Phage Antibodies to Distinguish Closely Related Species of Protozoan Parasites [PDF]
Disease Markers, 2000 Acanthamoeba are typically identified in the laboratory using culture and microscopic observation. In this paper we describe the isolation and specificity of antibody fragments that can be used for the identification of Acanthamoeba. A phage library expressing a large repertoire (approx.
Timothy Paget +4 more
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Specificity of SARS-CoV-2 antibody-detection assays against S and N protein among pre-COVID-19 sera from patients with protozoan and helminth parasitic infections [PDF]
Journal of Clinical Microbiology, 2021 ABSTRACT Background We aimed to assess the specificity of SARS-CoV-2 antibody detection assays among people with known tissue-borne parasitic infections. Methods We tested three SARS-CoV-2 antibody-detection assays (cPass SARS-CoV ...
Cedric P. Yansouni +12 more
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Adaptation of CUT&RUN for use in African trypanosomes.
PLoS ONE, 2023 This Cleavage Under Targets and Release Using Nuclease (CUT&RUN) protocol produces genomic occupancy data for a protein of interest in the protozoan parasite Trypanosoma brucei. The data produced is analyzed in a similar way as that produced by ChIP-seq.
Geneva Miller +4 more
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