Results 251 to 260 of about 5,065,448 (337)

Overexpression of CDT1 inhibits cell cycle progression at S phase by interacting with the mini‐chromosome maintenance complex and causes DNA damage

FEBS Open Bio, EarlyView.
CDT1 is an essential protein for DNA replication licensing that loads the MCM complex, the eukaryotic replicative DNA helicase, onto replication origins. Overexpression of CDT1 induces cell cycle arrest at the S phase. Here we showed CDT1 inhibits the progression of replication forks by interacting with the MCM complex, leading to the stalling and ...
Takashi Tsuyama, Nonoka Takayama, Rina Tanaka, Yuuki Arai, Yohko Yamaguchi, Yuko Nawata, Yutaro Azuma, Shusuke Tada   +7 more
wiley   +1 more source

Antibody Polyreactivity: A Challenger of Immune Paradigms. [PDF]

Immunology
Pashov AD, Dimitrov JD.
europepmc   +1 more source

HSP70 governs permeability and mechanotransduction in primary human endothelial cells

FEBS Open Bio, EarlyView.
HSP70 chemical inhibition reduces endothelial cell proliferation and increases permeability, the latter supported by normal interendothelial junctional protein distribution. HSP70 also plays a role in shear stress response, a hemodynamic force naturally present in blood vessels and correlated with vessel protection.
Andrea Pinto‐Martinez, Everton G. Melo, Isadora C. B. Pavan, Percíllia V. S. Oliveira, Luiza B. C. T. Coimbra, Thaís L. S. Araujo   +5 more
wiley   +1 more source

Human monoclonal antibodies to HPV16 show evidence for common developmental pathways and public epitopes. [PDF]

PLoS Pathog
Carter JJ, Hurlburt NK, Scherer EM, Singh S, Rodarte JV, Smith RA, Lewis P, Kinzelman R, Kieltyka J, Cabãn ME, Wipf GC, Pancera M, Galloway DA.   +12 more
europepmc   +1 more source

Molecular determinants of signal transduction in tropomyosin receptor kinases

FEBS Open Bio, EarlyView.
Tropomyosin receptor kinases control critical neuronal functions, but how do the same receptors produce diverse cellular responses? This review explores the structural mechanisms behind Trk signaling diversity, focusing on allosteric modulation and ligand bias.
Giray Enkavi
wiley   +1 more source

Pfs230 domain 12 is a potent malaria transmission-blocking vaccine candidate. [PDF]

Sci Adv
Inklaar MR, de Jong RM, Da DF, Hubregtse LL, Meijer M, Teelen K, Bekkering ET, Grievink S, van de Vegte-Bolmer M, van Gemert GJ, Stoter R, Nagaoka H, Tsuboi T, Takashima E, Spruijt CG, Vermeulen M, Dabire RK, Arinaitwe E, Cohuet A, Bousema T, Jore MM.   +20 more
europepmc   +1 more source

Specificity, cross-reactivity, and function of antibodies elicited by Zika virus infection

Science, 2016
Karin Stettler, M. Beltramello, Diego A. Espinosa, Victoria A. Graham, Antonino Cassotta, S. Bianchi, Fabrizia Vanzetta, A. Minola, S. Jaconi, F. Mele, Mathilde Foglierini, M. Pedotti, L. Simonelli, S. Dowall, B. Atkinson, E. Percivalle, C. Simmons, L. Varani, J. Blum, F. Baldanti, E. Cameroni, R. Hewson, E. Harris, A. Lanzavecchia, F. Sallusto, D. Corti   +25 more
semanticscholar   +1 more source

Day/night variations of myeloid and lymphoid cell subsets in the murine inguinal lymph node

FEBS Open Bio, EarlyView.
The circadian system is involved in the temporal regulation of the immune system. Our study reveals that two innate immune populations, NKT cells and neutrophils, predominate at the beginning of the day in healthy mice, highlighting how the time of day influences immune responses.
Paula M. Wagner, César G. Prucca, Lucia Boffelli, Virginia A. Piqueras, Silvia G. Correa, Mariana Maccioni, Mario E. Guido   +6 more
wiley   +1 more source

Glycolipid Antibodies in Patients With Chronic Idiopathic Axonal Polyneuropathy and Gluten Neuropathy. [PDF]

Eur J Neurol
Zis P, Artemiadis A, Halstead S, Hadjigeorgiou GM, Willison H, Hadjivassiliou M.   +5 more
europepmc   +1 more source

Serum house dust mite antibodies: predictor of increased bronchial responsiveness in adults of a community [PDF]

, 1996
Ernst Omenaas, Per Bakke, GE Eide, S. Elsayed, Amund Gulsvik   +4 more
openalex   +1 more source