Results 251 to 260 of about 3,666,403 (333)

Towards antibody-based immunotherapy development for platinum-resistant high-grade serous ovarian cancer. [PDF]

Sci Rep
Giedraityte Z, Aarnio N, Nait Mohamed FA.   +2 more
europepmc   +1 more source

Expanding the watch list for potential Ebola virus antibody escape mutations

, 2019
Jagdish Suresh Patel, Caleb J. Quates, Erin L. Johnson, F. Marty Ytreberg   +3 more
openalex   +2 more sources

DDX3X induces mesenchymal transition of endothelial cells by disrupting BMPR2 signaling

FEBS Open Bio, EarlyView.
Elevated DDX3X expression led to downregulation of BMPR2, a key regulator of endothelial homeostasis and function. Our co‐immunoprecipitation assays further demonstrated a molecular interaction between DDX3X and BMPR2. Notably, DDX3X promoted lysosomal degradation of BMPR2, thereby impairing its downstream signaling and facilitating endothelial‐to ...
Yu Zhang, Jing Wang, De‐Hui Qian, Yang‐Fan Lv, Tian‐Le Cheng, Da‐Peng Wang, Jing Zhang, Ye Fan   +7 more
wiley   +1 more source

Peptide-Based Plasmon-Enhanced Spectroscopic Immunoassay to Detect Immunity Against Cytomegalovirus. [PDF]

Biosensors (Basel)
Chandra Singh A, Sidhoum C, Payen H, Balakrishnan D, Juodkazis S, Østerbye T, Krishnamoorthy S.   +6 more
europepmc   +1 more source

ATP13A2 is involved in intracellular polyamine transport in lung epithelial cells

FEBS Open Bio, EarlyView.
Spermidine transport in lung epithelial cells involves the polyamine transporter ATP13A2. Cell proliferation is associated with the upregulation of ATP13A2. Polyamines are present in all living cells and are implicated in various crucial cellular processes such as proliferation, apoptosis and autophagy.
Yuta Hatori, Kohei Kawabata, Takanori Kubo, Takeo Kitazawa, Sae Kanai, Madoka Iwashita, Ami Hayashi, Hiroyuki Nishi, Mikihisa Takano   +8 more
wiley   +1 more source

A high-throughput platform for biophysical antibody developability assessment to enable AI/ML model training. [PDF]

MAbs
Arsiwala A, Bhatt R, van Niekerk L, Quintero-Cadena P, Ao X, Rosenbaum A, Bhatt A, Smith A, Yang Y, Anderson KC, Grippo L, Cao X, Cohen R, Patel J, Moller J, Allen O, Faraj A, Nandy A, Hocking J, Ergun A, Tural B, Salvador S, Jacobowitz J, Schaven K, Sherman M, Shah S, Tessier PM, Borhani DW.   +27 more
europepmc   +1 more source

TMC4 localizes to multiple taste cell types in the mouse taste papillae

FEBS Open Bio, EarlyView.
Transmembrane channel‐like 4 (TMC4), a voltage‐dependent chloride channel, plays a critical role in amiloride‐insensitive salty taste transduction. TMC4 is broadly expressed in all mature taste cell types, suggesting a possible involvement of multiple cell types in this pathway.
Momo Murata, Yoshikazu Saito, Yoichi Kasahara, Wataru Fujii, Takumi Misaka, Tomiko Asakura, Masataka Narukawa   +6 more
wiley   +1 more source

Conceptualization of fibroblast growth factor receptor 1 targeting nanomedicines. [PDF]

Explor Target Antitumor Ther
Ma Y, Guo M, Liu Y, Huang Z.
europepmc   +1 more source