Results 261 to 270 of about 3,219,836 (309)
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Endeavour, 1994
A century ago, in his private laboratory in Berlin, Paul Ehrlich conceived and developed the idea of using antibodies to target toxic molecules. Recent advances in genetic engineering have enormously extended the potential of this concept for the treatment of malignant diseases, by making it possible to isolate genes encoded for the antibody variable ...
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A century ago, in his private laboratory in Berlin, Paul Ehrlich conceived and developed the idea of using antibodies to target toxic molecules. Recent advances in genetic engineering have enormously extended the potential of this concept for the treatment of malignant diseases, by making it possible to isolate genes encoded for the antibody variable ...
openaire +2 more sources
Current Opinion in Biotechnology, 1991
Antibody engineering has received a boost from the development of an Escherichia coli expression system that now allows the screening of libraries with bacteria or phages. These random selection techniques can be applied using knowledge obtained from new X-ray structures of recombinant antibody domains, and anti-peptide antibodies.
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Antibody engineering has received a boost from the development of an Escherichia coli expression system that now allows the screening of libraries with bacteria or phages. These random selection techniques can be applied using knowledge obtained from new X-ray structures of recombinant antibody domains, and anti-peptide antibodies.
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Antibodies from phage antibody libraries
Journal of Immunological Methods, 2004Andrew R M, Bradbury, James D, Marks
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2019
The accurate and reliable determination of biologically active endogenous compounds in plasma, urine, and other body fluids for scientific or diagnostic purposes has been a challenge for many decades. In the past, the assessment of such compounds was difficult and tedious because specific and practical analytical tools were not available.
Redegeld, F. +3 more
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The accurate and reliable determination of biologically active endogenous compounds in plasma, urine, and other body fluids for scientific or diagnostic purposes has been a challenge for many decades. In the past, the assessment of such compounds was difficult and tedious because specific and practical analytical tools were not available.
Redegeld, F. +3 more
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Philosophical Transactions of the Royal Society of London. B, Biological Sciences, 1989
The antibody molecule is a therapeutic agent, designed by nature to bind to a wide range of antigen molecules and to trigger effector functions, such as complement lysis and cell-mediated killing. The genes encoding antibodies can be manipulated in vitro , allowing the binding sites for antigen and effector ...
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The antibody molecule is a therapeutic agent, designed by nature to bind to a wide range of antigen molecules and to trigger effector functions, such as complement lysis and cell-mediated killing. The genes encoding antibodies can be manipulated in vitro , allowing the binding sites for antigen and effector ...
openaire +2 more sources
Antibodies to combat viral infections: development strategies and progress
Nature Reviews Drug Discovery, 2022Giuseppe Pantaleo +2 more
exaly
International Journal of Dermatology, 1981
L L, Lorincz, K, Soltani, J E, Bernstein
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L L, Lorincz, K, Soltani, J E, Bernstein
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