Results 241 to 250 of about 211,312 (294)
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Antibody-dependent Cytotoxicity to Transitional Cells in Cystitis Cystica
Journal of Urology, 1981Serum from 20 children with urinary tract infections and proved cystitis cystica has been examined for antibody to a panel of established cell lines derived from normal urothelium and transitional cell carcinomas of the bladder. Antibody-dependent cytotoxicity was measured with serial dilutions of patient serum and lymphocytes from normal healthy ...
H N, Noe +3 more
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Origin of the antibody-dependent cytotoxic cell in man
Clinical Immunology and Immunopathology, 1977Abstract Antibody-dependent cell-mediated cytotoxicity (ADCC) against lymphoblastoid cells was absent in three cases of severe combined immunodeficiency prior to bone marrow transplantation. Post-transplantation, ADCC, T-cell function, and B-cell function were restored independently of each other.
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Damage of Liposomes in Antibody‐Dependent Cell‐Mediated Cytotoxicity
Scandinavian Journal of Immunology, 1977Lymphoid cells bearing Fc receptors are able to lyse antibody‐coated animal target Cells in an antibody‐dependent cell‐mediated cytotoxicity reaction. The results presented here show that liposomes consisting of sphingomyelin, cholesterol, and cardiolipid and coated by cardiolipidic antibodies could be destroyed by spleen or thymus cells. No alteration
D, Juy, A, Billecocq, M, Faure, C, Bona
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Antibody-Dependent Cell-Mediated Cytotoxicity in Humans
The Journal of Immunology, 1975Abstract Mononuclear cells from human peripheral blood are able to destroy alloantibody-coated target cells of a human lymphoblastoid line. The effector cell is a nonadherent, non-phagocytic, medium sized lymphoid cell. This cell is not detectable in early human fetuses.
Giorgio Trinchieri +3 more
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Surface properties of cells involved in antibody-dependent cytotoxicity
Cellular Immunology, 1976Abstract Using a recently developed technique for separating cells, the two cell types that mediate the destruction of antibody coated target cells, namely K cells and macrophages, have been characterized according to a series of cell surface markers.
Ramshaw, I A, Parish, C R
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SELECTIVE REACTIONS IN ANTIBODY-DEPENDENT CELL-MEDIATED CYTOTOXICITY
Transplantation, 1977Selective reactions associated with HLA specificity were sought in antibody-dependent cell-mediated cytotoxic tests against HLA-typed lymphoblastoid lines using operationally monospecific HLA sera and effector cells from healthy individuals. Precise detection of HLA specificities was disturbed by the presence of natural antibodies in HLA antiserum and ...
J, Takasugi, M, Takasugi
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Human lymphoblast cell lines: Antibody‐dependent cytotoxicity
European Journal of Immunology, 1975AbstractFive cell lines were isolated after prolonged culture of human buffy coat leukocytes. The cells consisted for the most part of lymphoblasts morphologically similar to those produced by in vivo or in vitro stimulation of small lymphocytes by antigens or mitogens. One of the lines possessed virus‐like particles of the Epstein‐Barr type.
J C, Lefebre +3 more
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Reversible blocking of antibody-dependent cell-mediated cytotoxicity
Cellular Immunology, 1977Abstract The ability of human peripheral blood lymphocytes to kill antibody-coated Chang liver cells in antibody-dependent cell-mediated cytotoxicity (ADCC) can be blocked with aggregated IgG (agg-IgG) or by soluble immune complexes. Dissociation of aggregates of IgG or immune complexes from the cell surface, however, resulted in partial recovery of ...
K, Sugamura, J B, Smith
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Journal of Visualized Experiments
The method for antibody-dependent, cell-mediated cytotoxicity (ADCC) represents an important tool to assess the efficacy of therapeutic antibodies in cancer immunotherapy. Evaluating ADCC activity in cancer cells is essential for the development and optimization of antibody-based treatments.
Kelvin Kam Yew, Kuan +4 more
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The method for antibody-dependent, cell-mediated cytotoxicity (ADCC) represents an important tool to assess the efficacy of therapeutic antibodies in cancer immunotherapy. Evaluating ADCC activity in cancer cells is essential for the development and optimization of antibody-based treatments.
Kelvin Kam Yew, Kuan +4 more
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Bovine antibody dependent cell-mediated cytotoxicity (ADCC) effector cells
Veterinary Immunology and Immunopathology, 1987ADCC effector cells from bovine blood were separated by centrifugation, adherence and rosetting techniques. Each enriched cell population, peripheral blood mononuclear cells (PBM), null lymphocytes, monocytes and neutrophils, was then examined for its capacity to mediate ADCC.
E L, Belden, H M, Peng
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