Results 231 to 240 of about 211,312 (294)

SNAP-Tag-Based Antibody-Drug Conjugates Targeting Epidermal Growth Factor Receptor 1, Epidermal Growth Factor Receptor 2, Trophoblast Cell-Surface Antigen 2, and Tissue Factor for Ovarian Cancer Treatment. [PDF]

ACS Omega
Zhang C, Sheng W, Mohiuddin TM, Al-Rawe M, Schmitz R, Niebert M, Zeppernick F, Meinhold-Heerlein I, Hussain AF.   +8 more
europepmc   +1 more source

A new, glycoengineered form of anti-CD20 monoclonal antibody, in treatment of multiple sclerosis. [PDF]

Ther Adv Neurol Disord
Selmaj K, Gold R, Selmaj I, Mycko MP.
europepmc   +1 more source

Development and non-clinical characterization of Procizumab (invobenitug): a humanized antibody neutralizing circulating DPP3. [PDF]

MAbs
Genest M, Van Lier D, Uba TI, Schroeter A, Picod A, Nordin H, Assad N, Marguerit G, Nguyen A, Bergmann A, Pickkers P, Mebazaa A, Santos K, Azibani F.   +13 more
europepmc   +1 more source

Development of a flow cytometry method to measure antidrug antibodies against CAR T cells. [PDF]

Immunohorizons
Day G, Sánchez-Martín FJ, Seavers L, Cadwallader K, Morgado-García S.   +4 more
europepmc   +1 more source

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Inhibition of antibody-dependent cell-mediated cytotoxicity by ethanol

Immunopharmacology, 1984
Ethanol has been shown to inhibit spontaneous cell-mediated cytotoxicity and antibody-dependent cell-mediated cytotoxicity in vitro in a dose-dependent manner. The effect was observed under differing assay conditions such as incubation time and effector: target cell ratio. Acetaldehyde, the primary metabolite of ethanol, did not inhibit these functions
N H Stacey, Neill H Stacey
exaly   +3 more sources

Antibody-Dependent Cell-Mediated Cytotoxicity

The Journal of Immunology, 1974
Abstract Macrophages obtained from peritoneal exudate are effector cells for antibody-dependent cytotoxicity. This effector function is independent of phagocytosis, and it is not inhibited by EDTA or aminophylline. Cells functionally similar to those in peritoneal exudate can be obtained from the spleen, but a functionally different ...
Juan Carlos Scornik, Humberto Cosenza
  +4 more sources

Enzymatic Enhancement of Cell-Mediated Cytotoxicity and Antibody-Dependent Cell Cytotoxicity

The Journal of Immunology, 1974
Abstract The effects of papain, trypsin, Pronase, neuraminidase, and phospholipase C on in vitro cell-mediated cytotoxicity (CMC) and antibody-dependent cell cytotoxicity (ADCC) have been studied in a syngeneic tumor system. Proteolytic enzyme treatment of lymphoid (effector) cells at low concentrations (<0.1 mg/ml) and for short ...
E, Kedar, M, Otiz de Landazuri, J L, Fahey   +2 more
openaire   +2 more sources

Antibody-dependent cell-mediated cytotoxicity in pigs

American Journal of Veterinary Research, 1982
SUMMARY Development of antibody-dependent cell-mediated cytotoxicity (adcc) was studied in cells obtained from porcine fetal and neonatal tissues. Pulmonary washouts, hepatic tissues, splenic tissues, and neutrophil fractions of blood were sources of cells.
A, Zarkower, M L, Eskew, W J, Scheuchenzuber, F G, Ferguson, F, Confer   +4 more
openaire   +2 more sources

Complement enhances antiviral antibody-dependent cell cytotoxicity

Nature, 1977
ANTIBODY-DEPENDENT cell cytotoxicity (ADCC) is an in vitro phenomenon that can be demonstrated with a variety of target cell systems and can be mediated by several types of effector cells1–3. The effectors in ADCC must bear a surface receptor for Fc, and this receptor binds with antibody which is in turn bound to the target cell.
B T, Rouse, A S, Grewal, L A, Babiuk
openaire   +2 more sources