Results 251 to 260 of about 211,312 (294)
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Antibody-dependent Cell-mediated Cytotoxicity due to a “Null” Lymphoid Cell
Nature New Biology, 1973ANTIBODY-COATED target cells may be killed by suspensions of lymphoid cells after depletion of active phagocytes1–4. Harding et al.5 and Van Boxel et al.6 also report that a non-thymus-derived lymphocyte is responsible for this antibody-dependent cell-mediated cytotoxicity in both the rat and mouse. The further observations that the cytotoxic cell acts
Greenberg, A H +3 more
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Antibody‐Dependent Cell‐Mediated Cytotoxicity in the Mouse
Scandinavian Journal of Immunology, 1974The surface characteristics of the mouse spleen cells mediating antibody‐dependent cytotoxicity (ADCC) against antigen‐coated chicken erythrocytes have been studied by several different column fractionation methods The major effector cells in this system were shown to be surface‐adherent and could be depleted from spleen cells by passage through glass ...
H F, Pross +3 more
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Different effector cell types in antibody-dependent cell-mediated cytotoxicity
Nature, 1975ANTIBODY-DEPENDENT cell-mediated cytotoxicity has been demonstrated in vitro using a number of continuously cultivated cell lines1,2 and nucleated erythrocytes3 as targets. Although the biological role of this cytotoxicity is not yet clear, it represents a potentially efficient cytotoxic mechanism and considerable interest has been shown in the ...
C J, Sanderson, I A, Clark, G A, Taylor
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Antibody-dependent cell-mediated cytotoxicity for cultured autologous melanoma cells
Cellular Immunology, 1981Abstract Sera from 33 patients with malignant melanoma were tested for antibody-dependent cellmediated cytotoxicity (ADCC) against cultured autologous melanoma cells prelabeled with [ 3 H]proline in a 36-h assay. Effector cells (autologous or from normal donors) were obtained by Ficoll-Hypaque separation of peripheral blood.
P O, Livingston +4 more
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Antibody-Dependent Lymphoid Cell-Mediated Cytotoxicity: Role of Complement
The Journal of Immunology, 1974Abstract Unsensitized lymphoid cells have the capacity to destroy antibody-coated target cells in vitro. Definitive studies to rule out the participation of complement (C) components in this reaction require a system with a complete absence of C components and with no possibility of endogenous synthesis of C by cells in culture.
J A, Van Boxel +3 more
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Influence of Hydrocortisone on Antibody-Dependent Lymphoid Cell Mediated Cytotoxicity
Immunological Communications, 1974Mice spleen lymphocytes which can be stimulated non-specifically by B cell mitogens such as lipopoly-saccharides (LPS) or a Nocardia water soluble mitogen (NWSM) are sensitive to cortisone. Experiments were performed in view of evaluating the influence of hydrocortisone on the lymphocyte-dependent antibody (LDA) cytotoxicity of mice spleen cells.
L, Chedid, D, Juy, C, Bona
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Antibody-dependent cell-mediated cytotoxicity (ADCC) in Aujeszky's disease
Archives of Virology, 1979Antibody-dependent cell-mediated cytotoxicity (ADCC) was studied using as targets 51Cr-labelled Vero cells infected with the Bartha strain of Aujeszky's disease virus (ADV). Using hyperimmune anti-ADV serum to sensitize the targets, porcine leukocytes from dextran-sedimented blood were found to be efficient effector cells yielding maximal 51Cr release ...
L A, Ashworth, G, Lloyd, A, Baskerville
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Antibody-dependent cell-mediated cytotoxicity
Survey of Immunologic Research, 1983E W, Fuson +5 more
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Antibody-Dependent Cell-Mediated Cytotoxicity
Gastroenterology, 1976Martin F. Kagnoff, Stephen Campbell
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