Results 211 to 220 of about 570,434 (333)

PI3Kdelta-driven expansion of regulatory B cells impairs protective immune responses to Trypanosoma congolense parasite infection. [PDF]

PLoS Pathog
Olayinka-Adefemi F, Wu X, Hou S, Sabzevary-Ghahfarokhi M, Wray-Dutra MN, Rawlings DJ, Uzonna J, Marshall AJ.   +7 more
europepmc   +1 more source

Table S1. Antibody Array Key from CCL2 Produced by the Glioma Microenvironment Is Essential for the Recruitment of Regulatory T Cells and Myeloid-Derived Suppressor Cells

, 2023
Alan L. Chang, Jason Miska, Derek A. Wainwright, Mahua Dey, Claudia V. Rivetta, Dou Yu, Deepak Kanojia, Katarzyna C. Pituch, Jian Qiao, Peter Pytel, Yu Han, Meijing Wu, Lingjiao Zhang, Craig Horbinski, Atique U. Ahmed, Maciej S. Lesniak   +15 more
openalex   +1 more source

Engineering tandem VHHs to target different epitopes to enhance antibody‐dependent cell‐mediated cytotoxicity

FEBS Open Bio, EarlyView.
Tandem VHH targeting distinct EGFR epitopes were engineered into a monovalent bispecific antibody (7D12‐EGA1‐Fc) with more potent ADCC without increasing affinity to EGFR. Structural modeling of 7D12‐EGA1‐Fc showed cross‐linking of separate EGFR domains to enhance CD16a engagement on NK cells.
Yuqiang Xu, Hao Jiang, Limin Chen, Fulai Zhou, Ying Jin, Mark L. Chiu   +5 more
wiley   +1 more source

Distinctive Immunological Signatures Define Foot-and-Mouth Disease Virus Persistence in Vaccinated Cattle. [PDF]

Transbound Emerg Dis
Zhang Z, Teng Z, Wang S, Mu S, Wei S, Dong H, Yin S, Zhang Y, Ding Y, Li Y, Sun S, Guo H.   +11 more
europepmc   +1 more source

Somatic cell hybrids producing antibodies specific for the tumor antigen of simian virus 40.

, 1978
Joanne Martinis, Carlo M. Croce
openalex   +2 more sources

Development of a Stable MGAT1− CHO Cell Line to Produce Clade C gp120 With Improved Binding to Broadly Neutralizing Antibodies [PDF]

, 2018
Rachel C. Doran, Bin Yu, Meredith Wright, Sara M. O’Rourke, Lu Yin, Jennie M. Richardson, Gabriel Byrne, Kathryn A. Mesa, Phillip W. Berman   +8 more
openalex   +1 more source

FGFR Like1 drives esophageal cancer progression via EMT, PI3K/Akt, and notch signalling: insights from clinical data and next‐generation sequencing analysis

FEBS Open Bio, EarlyView.
Clinical analysis reveals significant dysregulation of FGFRL1 in esophageal cancer (EC) patients. RNAi‐coupled next‐generation sequencing (NGS) and in vitro study reveal FGFRL1‐mediated EC progression via EMT, PI3K/Akt, and Notch pathways. Functional assays confirm its role in tumor growth, migration, and invasion.
Aprajita Srivastava, Anoop Saraya, Deepak Gunjan, Rinu Sharma   +3 more
wiley   +1 more source

TIM3-mediated differentiation of IL-10-producing CD25⁺ B cells by expanded regulatory T cells. [PDF]

J Mol Med (Berl)
Alhabbab RY, Mastronicola D, Lombardi G, Scottà C.   +3 more
europepmc   +1 more source

Studies on Optimization of a pH-shift Control Strategy for Producing Monoclonal Antibodies in Chinese Hamster Ovary Cell Cultures using a pH-Dependent Dynamic Model

, 2018
智治 鳳桐
openalex   +2 more sources

The effect of salubrinal on the endoplasmic reticulum stress pathway in heat‐stressed spermatogonial cells in vitro

FEBS Open Bio, EarlyView.
This study investigates the protective role of salubrinal against heat‐induced endoplasmic reticulum (ER) stress in mouse spermatogenic cells (GC1 and GC2). By modulating the ER stress pathway, salubrinal alleviates cellular stress and supports spermatogenic cell survival, suggesting its potential as a therapeutic candidate for heat‐related infertility.
Suna Karadeniz Saygili, Mustafa Oztatlici, Mahmut Kemal Ozbilgin   +2 more
wiley   +1 more source