Results 231 to 240 of about 556,937 (315)

Peripheral Neutrophil Activation and Extracellular Trap Formation in Amyotrophic Lateral Sclerosis

Annals of Clinical and Translational Neurology, EarlyView.
Markers of neutrophil activation are increased in plasma during ALS, and markers of NET formation associate with ALS survival. ABSTRACT Objectives Peripheral neutrophil levels in amyotrophic lateral sclerosis (ALS) inversely correlate with survival, suggesting a role for neutrophils in disease progression.
Lillia A. Baird, Haley McQuown, Jihyun Park, Samuel J. Teener, Ian F. Webber‐Davis, Andrew D. Carter, Dae‐Gyu Jang, Eva L. Feldman, Stephen A. Goutman, Benjamin J. Murdock   +9 more
wiley   +1 more source

The landscape of antibody production systems: recombinant expression for research, diagnostics and therapy. [PDF]

Front Bioeng Biotechnol
Wenzel EV, Al-Halabi-Frenzel L, Demiral S, Frenzel A, Gnann DC, Keitel MC, Lehmler N, Mukherjee T, Rauls J, Schirrmann T, Stańczyk PG, Steinke S, Terbrack J, Westerhoff S, Dübel S, Schubert M, Hust M, Bertoglio F.   +17 more
europepmc   +1 more source

Diagnostic Use of Testing for Novel Murine Autoantibodies for Sjögren Disease in the Rheumatology Outpatient Setting

Arthritis Care &Research, EarlyView.
Objective The goal was to assess the diagnostic performance of three novel autoantibodies (NA) for Sjögren disease (SjD) by comparing NA prevalence in patients with SjD, other autoimmune rheumatic diseases (ARDs), nonspecific chronic sialadenitis (CS), and controls.
Chadwick R. Johr, Michael D. George, Vatinee Y. Bunya, Nora Sandorfi, Mina Massaro‐Giordano, Frederick B. Vivino   +5 more
wiley   +1 more source

Protective immunity against Chagas disease induced by a superantigen-based chimeric DNA vaccine delivered by attenuated <i>Salmonella</i>. [PDF]

Front Immunol
Antonoglou MB, Sánchez Alberti A, Redolfi DM, Bivona AE, Noli Truant S, Sarratea MB, Cardoso A, Motta FN, Malchiodi EL, Fernández MM.   +9 more
europepmc   +1 more source

The role of mucosal immune dysregulation in the pathogenesis of immunoglobulin A nephropathy. [PDF]

Front Immunol
Ohyama Y, Tsuji Y, Tezuka H, Novak J, Takahashi K.   +4 more
europepmc   +1 more source

Rheumatologic Manifestations of Patients With Type B Insulin Resistance

Arthritis Care &Research, EarlyView.
Objective The objectives of this study were to identify laboratory and clinical features associated with type B insulin resistance (TBIR), a rare condition caused by autoantibodies that inhibit the insulin receptor, most frequently occurring in the setting of systemic lupus erythematosus (SLE), and to increase awareness of this rare, life‐threatening ...
S. Amara Ogbonnaya, Sandra G. Williams, Raphael A. Kirou, Marissa Lightbourne, Rebecca J. Brown   +4 more
wiley   +1 more source

Metabolic Reprogramming of B Cells in Cancer: Effects of Altered Energetics. [PDF]

Biology (Basel)
Sarkar UA, Ambareen N, Prasad P, Kamran M, Ghosh S.   +4 more
europepmc   +1 more source

β‐Catenin/c‐Myc Axis Modulates Autophagy Response to Different Ammonia Concentrations

Advanced Biology, Volume 9, Issue 3, March 2025.
Ammonia, detoxified by the liver into urea and glutamine, impacts autophagy differently at varying levels. Low ammonia activates autophagy via c‐Myc and β‐catenin, while high levels suppress it. Using Huh7 cells and Spf‐ash mice, c‐Myc's role in cytoprotective autophagy is revealed, offering insights into hyperammonemia and potential therapeutic ...
S. Sergio, B. Spedicato, G. Corallo, A. Inguscio, M. Greco, D. Musarò, D. Vergara, A. F. Muro, G. De Sabbata, L. R. Soria, N. Brunetti Pierri, M. Maffia   +11 more
wiley   +1 more source

Seasonal influenza mRNA vaccine induces stronger innate and comparable or better adaptive responses than licensed inactivated vaccines. [PDF]

NPJ Vaccines
Bermúdez-Méndez E, Lenart K, Arcoverde Cerveira R, Engstrand O, Hellgren F, Cagigi A, Ols S, Jasny E, Reinhardt A, Petsch B, Loré K.   +10 more
europepmc   +1 more source

Strain‐Programmable Luminescent Adhesive Patch With Tartrazine‐Mediated Optical Skin Clearing for Photochemical Tissue Bonding

Advanced Functional Materials, EarlyView.
We propose a suture‐complementary approach that integrates optical skin clearing with a strain‐programmable luminescent adhesive patch. Hyaluronic acid promotes transdermal delivery of tartrazine to improve optical clearing and stabilizes its interaction with a photosensitizer. Optical clearing increases the penetration depth of visible light into skin,
Seong‐Jong Kim, Kyungjoo Jo, Kwanghyeon Park, Jun Hee Kim, Jong Hyeong Cho, Inhoo Choi, Sei Kwang Hahn   +6 more
wiley   +1 more source