Results 221 to 230 of about 348,994 (265)
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[Heterogeneity of antibodies produced by individual cells].
Annales d'immunologie, 1977Recent experimental findings indicate that individual B cells can produce simultaneously heterogeneous Ig molecules. Three orders of heterogeneity have been described. (1) In two published cases of human myeloma, individual malignant cells produced Igkappa and Iglambda (case Im) or IgMlambda and IgGkappa (case Br).
P, Liacopoulos, J, Couderc
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Effect of antibiotics on the development of antibody-producing cells, in vitro
Biochemical Pharmacology, 1972Abstract Using the Mishell-Dutton technique † for culturing mouse spleen cells to produce hemolysin plaque-forming cells (PFC) in vitro , actinomycin D, puromycin or cycloheximide were added daily to determine antibiotic-sensitive sites. The culture period was functionally divided into three temporal phases: (a) An initial phase (0–24 hr) of ...
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Separation of mitogen-induced suppressor cells of human antibody-producing cells
Cellular Immunology, 1980Abstract Human antibody-forming cells were demonstrated by a plaque in agar technique following in vitro stimulation with either pokeweed mitogen or Cowan I strain of protein A-positive Staphylococcus aureus bacteria. We evaluated the effects on this antibody formation caused by the addition of cells which had been stimulated with PH A or Con A. Both
J T, Kurnick, F, Pandolfi, H, Wigzell
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Low number of antibody producing cells in patients with sickle cell anemia
Immunology Letters, 1992B cell function is impaired in patients with sickle cell anemia. Although the number of surface IgM positive cells was similar in sickle cell patients and controls, in vitro spontaneous IgM, and PWM stimulated IgA, IgM, and IgG synthesis was significantly lower in the patients than in controls.
N, Rautonen +5 more
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Toxin–antigen conjugates as selection tools for antibody producing cells
Journal of Immunological Methods, 2013The generation of antibodies with designated specificity requires cost-intensive and time-consuming screening procedures. Here we present a new method by which hybridoma cells can be selected based on the specificity of the produced antibody by the use of antigen-toxin-conjugates thus eliminating the need of a screening procedure.
Messerschmidt, Katrin, Heilmann, Katja
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A New Method for the Enumeration of Single Antibody-Producing Cells
The Journal of Immunology, 1968Summary A new method is described for the enumeration of single cells producing antibody against a pure protein preparation from Salmonella adelaide flagella. Cells with adherent bacteria, cultured in nutrient agar, give rise to bacteria adherence colonies which can be counted under low power magnification.
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Electron Micrography of Antibody-Producing Cells
Nature, 1965A E, BUSSARD, J L, BINET
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The Origin of Antibody-producing Cells in Experimental Synovitis
International Archives of Allergy and Applied Immunology, 2009G, Loewi, J, Dorling, L E, Glynn
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QUANTITATIVE INVESTIGATIONS OF IDIOTYPIC ANTIBODIES
Journal of Experimental Medicine, 1971A Nisonoff, Nisonoff Alfred
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