Results 111 to 120 of about 3,380,570 (289)

Author Correction: A Rift Valley fever mRNA vaccine elicits strong immune responses in mice and rhesus macaques

open access: yesnpj Vaccines, 2023
Ting Bian   +13 more
doaj   +1 more source

New Rh Antibody [PDF]

open access: green, 1953
A.S. Wiener
openalex   +1 more source

Antibodies, repertoires and microdevices in antibody discovery and characterization

open access: yesLab on a Chip
Essential in treating numerous diseases, novel therapeutic antibody candidates are needed. This critical review examines recent advances in microdevices and the challenges associated with candidate discovery and characterization.
Luca Johannes Schlotheuber   +2 more
openaire   +4 more sources

Immunogenicity Assessment of a 14-Valent Human Papillomavirus Vaccine Candidate in Mice

open access: yesVaccines
Background: Cervical cancer ranks as the fourth most common cancer affecting women globally, with HPV as the primary etiology agent. Prophylactic HPV vaccines have substantially reduced the incidence of cervical cancer.
Lei Bei   +13 more
doaj   +1 more source

Preclinical Characterization of Efficacy and Pharmacodynamic Properties of Finotonlimab, a Humanized Anti-PD-1 Monoclonal Antibody

open access: yesPharmaceuticals
Background/Objectives: Finotonlimab (SCTI10A) is a humanized anti-PD-1 antibody tested in Phase III trials for several solid tumor types. Methods: This study characterized the in vitro and in vivo efficacy, Fc-mediated effector function, and non-clinical
Yunqi Yao   +15 more
doaj   +1 more source

Protein-environment-sensitive computational epitope accessibility analysis from antibody dose-response data [PDF]

open access: yesarXiv
Antibodies are widely used in life-sciences and medical therapy. Yet, broadly applicable methods are missing to determine, in the biological system of choice, antibody specificity and its quantitative contribution to e.g. immunofluorescence stainings. Thereby, antibody-based data often needs to be seen with caution.
arxiv  

Modelling the effect of antibody depletion on dose-response behavior for common immunostaining protocols [PDF]

open access: yesarXiv
Dose-response curves of immunostaining experiments are commonly described as Langmuir isotherm. However, for common immunostaining protocols the equilibrium assumption is violated and the dose-response behavior is governed by antibody accumulation. If bound antibodies are replenished, i.e.
arxiv  

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