Results 111 to 120 of about 3,844,696 (336)

Lipid Metabolic Pathways Confer the Immunosuppressive Function of Myeloid-Derived Suppressor Cells in Tumor

Frontiers in Immunology, 2019
Myeloid-derived suppressor cells (MDSCs) play crucial roles in tumorigenesis and their inhibition is critical for successful cancer immunotherapy.
Dehong Yan, Adeleye O. Adeshakin, Adeleye O. Adeshakin, Meichen Xu, Meichen Xu, Lukman O. Afolabi, Lukman O. Afolabi, Guizhong Zhang, Youhai H. Chen, Xiaochun Wan, Xiaochun Wan   +10 more
doaj   +1 more source

The fingerprint of antimitochondrial antibodies and the etiology of primary biliary cholangitis [PDF]

, 2017
Zongwen Shuai, Jin‐Jun Wang, Madhu Badamagunta, Jinjung Choi, Guoxiang Yang, Weici Zhang, Thomas P. Kenny, Kathryn G. Guggenheim, Mark J. Kurth, Aftab A. Ansari, John C. Voss, Ross L. Coppel, Pietro Invernizzi, Patrick S.C. Leung, M. Eric Gershwin   +14 more
openalex   +1 more source

PYCR1 inhibition in bone marrow stromal cells enhances bortezomib sensitivity in multiple myeloma cells by altering their metabolism

Molecular Oncology, EarlyView.
This study investigated how PYCR1 inhibition in bone marrow stromal cells (BMSCs) indirectly affects multiple myeloma (MM) cell metabolism and viability. Culturing MM cells in conditioned medium from PYCR1‐silenced BMSCs impaired oxidative phosphorylation and increased sensitivity to bortezomib.
Inge Oudaert, Lauren van den Broecke, Osman Aksoy, Judith Lind, Sonia Vallet, Arne Van der Vreken, Gamze Ates, Ann Massie, Ken Maes, Kim De Veirman, Elke De Bruyne, Karin Vanderkerken, Klaus Podar, Eline Menu   +13 more
wiley   +1 more source

Mutation N856K in spike reduces fusogenicity and infectivity of Omicron BA.1

Signal Transduction and Targeted Therapy, 2023
Chunyun Sun, Huiyu Wang, Ji Yang, Desheng Kong, Yuning Chen, Haiyue Wang, Lingling Sun, Jianbo Lu, Min Teng, Liangzhi Xie   +9 more
doaj   +1 more source

Hemolysis related to intravenous immunoglobulins is dependent on the presence of anti‐blood group A and B antibodies and individual susceptibility [PDF]

, 2017
Orell Mielke, Stefano Fontana, Vesselina Goranova‐Marinova, Amgad Shebl, M. Spycher, Sandra Wymann, Billie L. Durn, John Philip Lawo, Alphonse Hubsch, Abdulgabar Salama   +9 more
openalex   +1 more source

In vitro properties of patient serum predict clinical outcome after high dose rate brachytherapy of hepatocellular carcinoma

Molecular Oncology, EarlyView.
Following high dose rate brachytherapy (HDR‐BT) for hepatocellular carcinoma (HCC), patients were classified as responders and nonresponders. Post‐therapy serum induced increased BrdU incorporation and Cyclin E expression of Huh7 and HepG2 cells in nonresponders, but decreased levels in responders.
Lukas Salvermoser, Jan Niklas Schäfer, Shraga Nahum Goldberg, Philipp Maximilian Kazmierczak, Moritz Nikolaus Gröper, Philipp Franz Linden, Elif Öcal, Tanja Burkard, Stefanie Corradini, Najib Ben Khaled, Moritz Wildgruber, Max Seidensticker, Jens Ricke, Matthias Stechele, Marianna Alunni‐Fabbroni   +14 more
wiley   +1 more source

Antibody Production Remains Intact Despite Loss of Bone Marrow B cells in Murine Norovirus InfectedStat1^–/–Mice

, 2021
Daniel E Eldridge, Charlie C Hsu
openalex   +2 more sources

Efficacy and safety of cosibelimab, an anti-PD-L1 antibody, in metastatic cutaneous squamous cell carcinoma [PDF]

, 2023
Philip R. Clingan, Rahul Ladwa, Daniel Brungs, Dean Laurence Harris, Margaret McGrath, Susan Arnold, Jermaine Coward, Samuel Fourie, A. Kurochkin, Daniel R Malan, Andrew Mant, Vinay Sharma, Hong Shue, Andrea Tazbirkova, Miguel‐Ángel Berciano‐Guerrero, Chaiyut Charoentum, Stéphane Dalle, Arunee Dechaphunkul, Oleksandr Dudnichenko, P. Koralewski, Iwona Ługowska, Henri Montaudié, Eva Muñoz‐Couselo, Virote Sriuranpong, James Oliviero, Jayesh Desai   +25 more
openalex   +1 more source

Inhibition of CDK9 enhances AML cell death induced by combined venetoclax and azacitidine

Molecular Oncology, EarlyView.
The CDK9 inhibitor AZD4573 downregulates c‐MYC and MCL‐1 to induce death of cytarabine (AraC)‐resistant AML cells. This enhances VEN + AZA‐induced cell death significantly more than any combination of two of the three drugs in AraC‐resistant AML cells.
Shuangshuang Wu, Jianlei Zhao, Aaban Asfar Azmi, Avanti Gupte, Jenna Thibodeau, Shuang Liu, Jinli Yang, Guan Wang, Holly Edwards, Lisa A. Polin, Juiwanna Kushner, Sijana H. Dzinic, Kathryn White, Julie Boerner, Maik Hüttemann, Jay Yang, Yue Wang, Jeffrey W. Taub, Yubin Ge   +18 more
wiley   +1 more source

Highly sensitive quantification of human total VEGF-A with a novel ELISA

Bone Reports, 2020
Andreea Ana-Maria Suciu, Elisabeth Gadermaier, Jacqueline Wallwitz, Gabriela Berg, Gottfried Himmler   +4 more
doaj   +1 more source