Results 11 to 20 of about 5,128,022 (309)

Primary vs. Secondary Antibody Deficiency: Clinical Features and Infection Outcomes of Immunoglobulin Replacement [PDF]

open access: yes, 2014
Secondary antibody deficiency can occur as a result of haematological malignancies or certain medications, but not much is known about the clinical and immunological features of this group of patients as a whole. Here we describe a cohort of 167 patients
AA Bousfiha   +55 more
core   +6 more sources

A Rift Valley fever mRNA vaccine elicits strong immune responses in mice and rhesus macaques

open access: yesnpj Vaccines, 2023
Rift Valley fever virus (RVFV) is listed as a priority pathogen by the World Health Organization (WHO) because it causes serious and fatal disease in humans, and there are currently no effective countermeasures.
Ting Bian   +13 more
doaj   +1 more source

An adenovirus-vectored RVF vaccine confers complete protection against lethal RVFV challenge in A129 mice

open access: yesFrontiers in Microbiology, 2023
Instruction: Rift valley fever virus (RVFV) is a mosquito-transmitted bunyavirus that causes severe disease in animals and humans. Nevertheless, there are no vaccines applied to prevent RVFV infection for human at present.
Meng Hao   +10 more
doaj   +1 more source

Antibodies and antibody-derived analytical biosensors [PDF]

open access: yesEssays in Biochemistry, 2016
The rapid diagnosis of many diseases and timely initiation of appropriate treatment are critical determinants that promote optimal clinical outcomes and general public health. Biosensors are now being applied for rapid diagnostics due to their capacity for point-of-care use with minimum need for operator input.
Hannah Byrne   +2 more
openaire   +3 more sources

IgG Fc engineering to modulate antibody effector functions

open access: yesProtein & Cell, 2017
Therapeutic monoclonal antibodies are among the most effective biotherapeutics to date. An important aspect of antibodies is their ability to bind antigen while at the same time recruit immune effector functions.
Xinhua Wang   +2 more
doaj   +1 more source

Not All Antibodies Are Created Equal: Factors That Influence Antibody Mediated Rejection. [PDF]

open access: yes, 2017
Consistent with Dr. Paul Terasaki's "humoral theory of rejection" numerous studies have shown that HLA antibodies can cause acute and chronic antibody mediated rejection (AMR) and decreased graft survival. New evidence also supports a role for antibodies
Butler, Carrie L   +3 more
core   +8 more sources

Authorship Weightage Algorithm for Academic Publications: A New Calculation and ACES Webserver for Determining Expertise

open access: yesMethods and Protocols, 2021
Despite the public availability, finding experts in any field when relying on academic publications can be challenging, especially with the use of jargons.
Wei-Ling Wu   +5 more
doaj   +1 more source

Convergent Antibody Responses to SARS-CoV-2 in Convalescent Individuals

open access: yesNature, 2020
During the coronavirus disease-2019 (COVID-19) pandemic, severe acute respiratory syndrome-related coronavirus-2 (SARS-CoV-2) has led to the infection of millions of people and has claimed hundreds of thousands of lives. The entry of the virus into cells
D. Robbiani   +45 more
semanticscholar   +1 more source

Antibodies and tuberculosis

open access: yesTuberculosis, 2016
Tuberculosis (TB) remains a major public health problem internationally, causing 9.6 million new cases and 1.5 million deaths worldwide in 2014. The Bacillus Calmette-Guérin vaccine is the only licensed vaccine against TB, but its protective effect does not extend to controlling the development of infectious pulmonary disease in adults. The development
Gavin R. Screaton   +5 more
openaire   +5 more sources

Antibody Conjugation and Formulation [PDF]

open access: yes, 2019
In an era where ultra-high antibody concentrations, high viscosities, low volumes, auto-injectors, and long storage requirements are already complex problems with the current unconjugated monoclonal antibodies on the market the formulation demands for ...
Alves, Nathan J.
core   +1 more source

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