Results 11 to 20 of about 5,125,209 (406)

Antibody responses to SARS-CoV-2 in patients of novel coronavirus disease 2019

medRxiv, 2020
Summary Background The novel coronavirus SARS-CoV-2 is a newly emerging virus. The antibody response in infected patient remains largely unknown, and the clinical values of antibody testing have not been fully demonstrated.
Juanjuan Zhao, Q. Yuan, Haiyan Wang, Wei Liu, X. Liao, Yingying Su, Xin Wang, Jing Yuan, Tingdong Li, Jin-xiu Li, Shen Qian, Congming Hong, Fuxiang Wang, Yingxia Liu, Zhaoqin Wang, Qing He, Zhiyong Li, B. He, Tianying Zhang, Yang Fu, S. Ge, Lei Liu, Jun Zhang, N. Xia, Zheng Zhang   +24 more
semanticscholar   +1 more source

Peptides, Antibodies, Peptide Antibodies and More [PDF]

International Journal of Molecular Sciences, 2019
The applications of peptides and antibodies to multiple targets have emerged as powerful tools in research, diagnostics, vaccine development, and therapeutics. Antibodies are unique since they, in theory, can be directed to any desired target, which illustrates their versatile nature and broad spectrum of use as illustrated by numerous applications of ...
Nicole Trier, Paul Hansen, Gunnar Houen
openaire   +5 more sources

Antibodies and antibody-derived analytical biosensors [PDF]

Essays in Biochemistry, 2016
The rapid diagnosis of many diseases and timely initiation of appropriate treatment are critical determinants that promote optimal clinical outcomes and general public health. Biosensors are now being applied for rapid diagnostics due to their capacity for point-of-care use with minimum need for operator input.
Hannah Byrne, Richard O'Kennedy, Shikha Sharma   +2 more
openaire   +3 more sources

IgG Fc engineering to modulate antibody effector functions

Protein & Cell, 2017
Therapeutic monoclonal antibodies are among the most effective biotherapeutics to date. An important aspect of antibodies is their ability to bind antigen while at the same time recruit immune effector functions.
Xinhua Wang, Mary Mathieu, Randall J. Brezski   +2 more
doaj   +1 more source

An adenovirus-vectored RVF vaccine confers complete protection against lethal RVFV challenge in A129 mice

Frontiers in Microbiology, 2023
Instruction: Rift valley fever virus (RVFV) is a mosquito-transmitted bunyavirus that causes severe disease in animals and humans. Nevertheless, there are no vaccines applied to prevent RVFV infection for human at present.
Meng Hao, Ting Bian, Guangcheng Fu, Yi Chen, Ting Fang, Chuanyi Zhao, Shuling Liu, Changming Yu, Jianmin Li, Jianmin Li, Wei Chen   +10 more
doaj   +1 more source

Convergent Antibody Responses to SARS-CoV-2 in Convalescent Individuals

Nature, 2020
During the coronavirus disease-2019 (COVID-19) pandemic, severe acute respiratory syndrome-related coronavirus-2 (SARS-CoV-2) has led to the infection of millions of people and has claimed hundreds of thousands of lives. The entry of the virus into cells
D. Robbiani, C. Gaebler, F. Muecksch, Julio C. C. Lorenzi, Zijun Wang, A. Cho, Marianna Agudelo, C. Barnes, A. Gazumyan, Shlomo Finkin, Thomas Hägglöf, Thiago Y. Oliveira, Charlotte Viant, A. Hurley, Hans-Heinrich Hoffmann, Katrina G. Millard, R. Kost, M. Cipolla, Kristie M Gordon, Filippo Bianchini, Spencer T Chen, Victor Ramos, R. Patel, Juan P Dizon, I. Shimeliovich, Pilar Mendoza, H. Hartweger, Lilian Nogueira, M. Pack, Jill Horowitz, F. Schmidt, Y. Weisblum, E. Michailidis, Alison W. Ashbrook, Eric Waltari, J. Pak, Kathryn E Huey-Tubman, Nicholas S Koranda, Pauline R. Hoffman, A. West, C. Rice, T. Hatziioannou, P. Bjorkman, P. Bieniasz, M. Caskey, M. Nussenzweig   +45 more
semanticscholar   +1 more source

Antibodies and tuberculosis

Tuberculosis, 2016
Tuberculosis (TB) remains a major public health problem internationally, causing 9.6 million new cases and 1.5 million deaths worldwide in 2014. The Bacillus Calmette-Guérin vaccine is the only licensed vaccine against TB, but its protective effect does not extend to controlling the development of infectious pulmonary disease in adults. The development
Gavin R. Screaton, Robert J. Wilkinson, Ashley Jacobs, Ashley Jacobs, Juthathip Mongkolsapaya, Helen McShane   +5 more
openaire   +5 more sources

Tropomyosin antibody: the specific localization of tropomyosin in nonmuscle cells [PDF]

, 1975
An antibody against purified chicken skeletal muscle tropomyosin is used in indirect immunofluorescence to visualize the localization of tropomyosin in a variety of nonmuscle cells.
Lazarides, Elias
core   +2 more sources

Safety, activity, and immune correlates of anti-PD-1 antibody in cancer.

New England Journal of Medicine, 2012
BACKGROUND Blockade of programmed death 1 (PD-1), an inhibitory receptor expressed by T cells, can overcome immune resistance. We assessed the antitumor activity and safety of BMS-936558, an antibody that specifically blocks PD-1.
S. Topalian, F. Hodi, J. Brahmer, S. Gettinger, David C. Smith, David F. McDermott, J. Powderly, Richard D. Carvajal, J. Sosman, M. Atkins, P. Leming, D. Spigel, S. Antonia, L. Horn, Charles G. Drake, D. Pardoll, Lieping Chen, W. Sharfman, Robert A. Anders, J. Taube, T. McMiller, Haiying Xu, A. Korman, M. Jure-Kunkel, S. Agrawal, D. McDonald, G. Kollia, A. Gupta, J. Wigginton, M. Sznol   +29 more
semanticscholar   +1 more source

A neutralizing human antibody binds to the N-terminal domain of the Spike protein of SARS-CoV-2

Science, 2020
Hitting SARS-CoV-2 in a new spot A key target for therapeutic antibodies against severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is the spike protein, a trimeric protein complex with each monomer comprising an S1 and an S2 domain that ...
Xiangyang Chi, R. Yan, Jun Zhang, Guanying Zhang, Yuanyuan Zhang, Meng Hao, Zhe Zhang, Pengfei Fan, Yunzhu Dong, Yilong Yang, Zhengshan Chen, Yingying Guo, Jinlong Zhang, Yaning Li, Xiaohong Song, Yi Chen, L. Xia, L. Fu, L. Hou, Junjie Xu, Changming Yu, Jianmin Li, Qiang Zhou, Wei Chen   +23 more
semanticscholar   +1 more source