A Rift Valley fever mRNA vaccine elicits strong immune responses in mice and rhesus macaques
npj Vaccines, 2023 Rift Valley fever virus (RVFV) is listed as a priority pathogen by the World Health Organization (WHO) because it causes serious and fatal disease in humans, and there are currently no effective countermeasures.
Ting Bian +13 more
doaj +1 more source
IgG Fc engineering to modulate antibody effector functions
Protein & Cell, 2017 Therapeutic monoclonal antibodies are among the most effective biotherapeutics to date. An important aspect of antibodies is their ability to bind antigen while at the same time recruit immune effector functions.
Xinhua Wang +2 more
doaj +1 more source
Tropomyosin antibody: the specific localization of tropomyosin in nonmuscle cells [PDF]
, 1975 An antibody against purified chicken skeletal muscle tropomyosin is used in indirect immunofluorescence to visualize the localization of tropomyosin in a variety of nonmuscle cells.
Lazarides, Elias
core +2 more sources
Methods and Protocols, 2021 Despite the public availability, finding experts in any field when relying on academic publications can be challenging, especially with the use of jargons.
Wei-Ling Wu +5 more
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Frontiers in Microbiology, 2023 Instruction: Rift valley fever virus (RVFV) is a mosquito-transmitted bunyavirus that causes severe disease in animals and humans. Nevertheless, there are no vaccines applied to prevent RVFV infection for human at present.
Meng Hao +10 more
doaj +1 more source
GPI-Anchored Fibromodulin as a Novel Target in Chronic Lymphocytic Leukemia: Diagnostic and Therapeutic Implications [PDF]
Iranian Journal of Immunology, 2019 Background: We have previously reported the aberrant expression of Fibromodulin (FMOD) in patients with chronic lymphocytic leukemia (CLL). Although FMOD has been considered as a cytoplasmic or secretory protein, we discovered the cell surface expression
Lia Farahi +8 more
doaj +1 more source
A comprehensive proteogenomic study of the human Brucella vaccine strain 104 M
BMC Genomics, 2017 Background Brucella spp. are Gram-negative, facultative intracellular pathogens that cause brucellosis in both humans and animals. The B. abortus vaccine strain 104 M is the only vaccine available in China for the prevention of brucellosis in humans ...
Xiaodong Zai +12 more
doaj +1 more source
Challenges and developments in universal vaccine design against SARS-CoV-2 variants
npj Vaccines, 2022 The emergence of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) had become a global concern because of its unexpectedly high pathogenicity and transmissibility.
Fangxin Zhao +4 more
doaj +1 more source
Combined DNA extraction and antibody elution from filter papers for the assessment of malaria transmission intensity in epidemiological studies. [PDF]
, 2013 BACKGROUND: Informing and evaluating malaria control efforts relies on knowledge of local transmission dynamics. Serological and molecular tools have demonstrated great sensitivity to quantify transmission intensity in low endemic settings where the ...
Baidjoe, Amrish +13 more
core +3 more sources
Regioselective and stoichiometrically controlled conjugation of photodynamic sensitizers to a HER2 targeting antibody fragment [PDF]
, 2014 The rapidly increasing interest in the synthesis of antibody–drug conjugates as powerful targeted anticancer agents demonstrates the growing appreciation of the power of antibodies and antibody fragments as highly selective targeting moieties.
Boyle, Ross W. +6 more
core +1 more source