Results 11 to 20 of about 5,128,022 (309)
Primary vs. Secondary Antibody Deficiency: Clinical Features and Infection Outcomes of Immunoglobulin Replacement [PDF]
Secondary antibody deficiency can occur as a result of haematological malignancies or certain medications, but not much is known about the clinical and immunological features of this group of patients as a whole. Here we describe a cohort of 167 patients
AA Bousfiha+55 more
core +6 more sources
A Rift Valley fever mRNA vaccine elicits strong immune responses in mice and rhesus macaques
Rift Valley fever virus (RVFV) is listed as a priority pathogen by the World Health Organization (WHO) because it causes serious and fatal disease in humans, and there are currently no effective countermeasures.
Ting Bian+13 more
doaj +1 more source
Instruction: Rift valley fever virus (RVFV) is a mosquito-transmitted bunyavirus that causes severe disease in animals and humans. Nevertheless, there are no vaccines applied to prevent RVFV infection for human at present.
Meng Hao+10 more
doaj +1 more source
Antibodies and antibody-derived analytical biosensors [PDF]
The rapid diagnosis of many diseases and timely initiation of appropriate treatment are critical determinants that promote optimal clinical outcomes and general public health. Biosensors are now being applied for rapid diagnostics due to their capacity for point-of-care use with minimum need for operator input.
Hannah Byrne+2 more
openaire +3 more sources
IgG Fc engineering to modulate antibody effector functions
Therapeutic monoclonal antibodies are among the most effective biotherapeutics to date. An important aspect of antibodies is their ability to bind antigen while at the same time recruit immune effector functions.
Xinhua Wang+2 more
doaj +1 more source
Not All Antibodies Are Created Equal: Factors That Influence Antibody Mediated Rejection. [PDF]
Consistent with Dr. Paul Terasaki's "humoral theory of rejection" numerous studies have shown that HLA antibodies can cause acute and chronic antibody mediated rejection (AMR) and decreased graft survival. New evidence also supports a role for antibodies
Butler, Carrie L+3 more
core +8 more sources
Despite the public availability, finding experts in any field when relying on academic publications can be challenging, especially with the use of jargons.
Wei-Ling Wu+5 more
doaj +1 more source
Convergent Antibody Responses to SARS-CoV-2 in Convalescent Individuals
During the coronavirus disease-2019 (COVID-19) pandemic, severe acute respiratory syndrome-related coronavirus-2 (SARS-CoV-2) has led to the infection of millions of people and has claimed hundreds of thousands of lives. The entry of the virus into cells
D. Robbiani+45 more
semanticscholar +1 more source
Tuberculosis (TB) remains a major public health problem internationally, causing 9.6 million new cases and 1.5 million deaths worldwide in 2014. The Bacillus Calmette-Guérin vaccine is the only licensed vaccine against TB, but its protective effect does not extend to controlling the development of infectious pulmonary disease in adults. The development
Gavin R. Screaton+5 more
openaire +5 more sources
Antibody Conjugation and Formulation [PDF]
In an era where ultra-high antibody concentrations, high viscosities, low volumes, auto-injectors, and long storage requirements are already complex problems with the current unconjugated monoclonal antibodies on the market the formulation demands for ...
Alves, Nathan J.
core +1 more source