Modelling bispecific monoclonal antibody interaction with two cell membrane targets indicates the importance of surface diffusion [PDF]
, 2016 We have developed a mathematical framework for describing a bispecific monoclonal antibody interaction with two independent membrane-bound targets that are expressed on the same cell surface.
Argungu, Maryam +8 more
core +1 more source
Microbiology Spectrum, 2014 ABSTRACT A brief outline of antibody structure is followed by highlights from several recently determined crystal structures of human, antiviral Fabs. These Fabs all have novel structural features that allow them to potently and broadly neutralize their targets.
Robyn L, Stanfield, Ian A, Wilson
openaire +2 more sources
Nanoparticles for live cell microscopy: A surface-enhanced Raman scattering perspective. [PDF]
, 2017 Surface enhanced Raman scattering (SERS) nanoparticles are an attractive alternative to fluorescent probes for biological labeling because of their photostability and multiplexing capabilities.
Candas, Demet +7 more
core +1 more source
Fc-Based Recombinant Henipavirus Vaccines Elicit Broad Neutralizing Antibody Responses in Mice
Viruses, 2020 The genus Henipavirus (HNVs) includes two fatal viruses, namely Nipah virus (NiV) and Hendra virus (HeV). Since 1994, NiV and HeV have been endemic to the Asia–Pacific region and responsible for more than 600 cases of infections. Two emerging HNVs, Ghana
Yaohui Li +9 more
doaj +1 more source
Therapeutic antibodies: current state and future trends--is a paradigm change coming soon? [PDF]
, 2008 Antibody-based therapeutics currently enjoy unprecedented success, growth in research and revenues, and recognition of their potential. It appears that the promise of the "magic bullet" has largely been realized.
Dimitrov, Dimiter S, Marks, James D
core +1 more source
Species- and organ-specificity of secretory proteins derived from human prostate and seminal vesicles [PDF]
, 1990 Polyclonal antibodies against semenogelin (SG) isolated from human seminal vesicle secretion and acid phosphatase (PAP), β‐microseminoprotein (β‐MSP), and Prostate‐Specific Antigen (PSA) derived from human prostatic fluid, as well as a monoclonal ...
Abrahamsson, P. ‐A, +6 more
core +2 more sources
A novel one-step approach for the construction of yeast surface display Fab antibody libraries
Microbial Cell Factories, 2018 Background Yeast surface display (YSD) has proven to be a versatile platform technology for antibody discovery. However, the construction of antibody Fab libraries typically is a tedious three-step process that involves the generation of heavy chain as ...
Simon Rosowski +10 more
doaj +1 more source
Antibodies for immunolabeling by light and electron microscopy : not for the faint hearted [PDF]
, 2014 Reliable antibodies represent crucial tools in the arsenal of the cell biologist and using them to localize antigens for immunocytochemistry is one of their most important applications.
Griffiths, Gareth, Lucocq, John Milton
core +1 more source
Seed-produced anti-globulin VHH-Fc antibodies retrieve globulin precursors in the insoluble fraction and modulate the Arabidopsis thaliana seed subcellular morphology [PDF]
, 2020 Key message Nanobody-heavy chain (VHH-Fc) antibody formats have the potential to immunomodulate even highly accumulating proteins and provide a valuable tool to experimentally modulate the subcellular distribution of seed storage proteins.
Altmann, Friedrich +7 more
core +2 more sources
Development and validation of an ELISA to detect antibodies to Corynebacterium pseudotuberculosis in ovine sera [PDF]
, 2007 Several enzyme-linked immunosorbent assays (ELISAs) have been developed for the detection of antibodies to Corynebacterium pseudotuberculosis, the causative agent of caseous lymphadenitis (CLA). However, none are commercially available in the UK.
Bailey, Mick +2 more
core +5 more sources