Results 31 to 40 of about 3,830,389 (286)

An integrated mammalian library approach for optimization and enhanced microfluidics-assisted antibody hit discovery

open access: yesArtificial Cells, Nanomedicine, and Biotechnology, 2023
Recent years have seen the development of a variety of mammalian library approaches for display and secretion mode. Advantages include library approaches for engineering, preservation of precious immune repertoires and their repeated interrogation, as ...
Ramona Gaa   +7 more
doaj   +1 more source

Development and validation of an ELISA to detect antibodies to Corynebacterium pseudotuberculosis in ovine sera [PDF]

open access: yes, 2007
Several enzyme-linked immunosorbent assays (ELISAs) have been developed for the detection of antibodies to Corynebacterium pseudotuberculosis, the causative agent of caseous lymphadenitis (CLA). However, none are commercially available in the UK.
Bailey, Mick   +2 more
core   +5 more sources

Platelet-collagen adhesion: evidence for participation of antigenically distinct entities. [PDF]

open access: yes, 1984
Univalent antibody fragments prepared from a rabbit antiserum raised against whole human platelets completely inhibited adhesion of platelets to immobilized trimeric collagen in a defined, Mg2+-dependent, adhesion assay.
Barondes, SH, Shadle, PJ
core   +2 more sources

Construction and Immunological Evaluation of an Adenoviral Vector-Based Vaccine Candidate for Lassa Fever

open access: yesViruses, 2021
Lassa virus (LASV) is a rodent-borne arenavirus circulating in West African regions that causes Lassa fever (LF). LF is normally asymptomatic at the initial infection stage, but can progress to severe disease with multiorgan collapse and hemorrhagic ...
Meirong Wang   +8 more
doaj   +1 more source

Modelling bispecific monoclonal antibody interaction with two cell membrane targets indicates the importance of surface diffusion [PDF]

open access: yes, 2016
We have developed a mathematical framework for describing a bispecific monoclonal antibody interaction with two independent membrane-bound targets that are expressed on the same cell surface.
Argungu, Maryam   +8 more
core   +1 more source

Unclassified autoimmune pancreatitis mimicking pancreatic cancer [PDF]

open access: yes, 2019
A 24-year-old black male presented with a 1-week obstructive jaundice and intermittent abdominal pain, with no significant weight loss and an unsuspicious abdominal exam.
Alves, A   +3 more
core   +1 more source

Fc-Based Recombinant Henipavirus Vaccines Elicit Broad Neutralizing Antibody Responses in Mice

open access: yesViruses, 2020
The genus Henipavirus (HNVs) includes two fatal viruses, namely Nipah virus (NiV) and Hendra virus (HeV). Since 1994, NiV and HeV have been endemic to the Asia–Pacific region and responsible for more than 600 cases of infections. Two emerging HNVs, Ghana
Yaohui Li   +9 more
doaj   +1 more source

A platform-agnostic, function first-based antibody discovery strategy using plasmid-free mammalian expression of antibodies

open access: yesmAbs, 2021
Hybridoma technology has been valuable in the development of therapeutic antibodies. More recently, antigen-specific B-cell selection and display technologies are also gaining importance. A major limitation of these approaches used for antibody discovery
Ruijun Zhang   +15 more
doaj   +1 more source

Intrathecal B-cell activation in LGI1 antibody encephalitis. [PDF]

open access: yes, 2020
ObjectiveTo study intrathecal B-cell activity in leucine-rich, glioma-inactivated 1 (LGI1) antibody encephalitis. In patients with LGI1 antibodies, the lack of CSF lymphocytosis or oligoclonal bands and serum-predominant LGI1 antibodies suggests a ...
Dandekar, Ravi   +13 more
core  

Nanoparticles for live cell microscopy: A surface-enhanced Raman scattering perspective. [PDF]

open access: yes, 2017
Surface enhanced Raman scattering (SERS) nanoparticles are an attractive alternative to fluorescent probes for biological labeling because of their photostability and multiplexing capabilities.
Candas, Demet   +7 more
core   +1 more source

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