Results 41 to 50 of about 5,128,022 (309)

Unclassified autoimmune pancreatitis mimicking pancreatic cancer [PDF]

, 2019
A 24-year-old black male presented with a 1-week obstructive jaundice and intermittent abdominal pain, with no significant weight loss and an unsuspicious abdominal exam.
Alves, A, Marinho, R, Nunes, V, Pignatelli, N   +3 more
core   +1 more source

A human monoclonal antibody blocking SARS-CoV-2 infection

Nature Communications, 2020
The emergence of the novel human coronavirus SARS-CoV-2 in Wuhan, China has caused a worldwide epidemic of respiratory disease (COVID-19). Vaccines and targeted therapeutics for treatment of this disease are currently lacking.
Chunyan Wang, Wentao Li, D. Drabek, Nisreen M. A. Okba, R. van Haperen, A. Osterhaus, F. V. van Kuppeveld, B. Haagmans, F. Grosveld, B. Bosch   +9 more
semanticscholar   +1 more source

Complete map of SARS-CoV-2 RBD mutations that escape the monoclonal antibody LY-CoV555 and its cocktail with LY-CoV016

bioRxiv, 2021
Monoclonal antibodies and antibody cocktails are a promising therapeutic and prophylaxis for COVID-19. However, ongoing evolution of SARS-CoV-2 can render monoclonal antibodies ineffective.
Tyler N. Starr, Allison J. Greaney, A. Dingens, J. Bloom   +3 more
semanticscholar   +1 more source

A platform-agnostic, function first-based antibody discovery strategy using plasmid-free mammalian expression of antibodies

mAbs, 2021
Hybridoma technology has been valuable in the development of therapeutic antibodies. More recently, antigen-specific B-cell selection and display technologies are also gaining importance. A major limitation of these approaches used for antibody discovery
Ruijun Zhang, Ponraj Prabakaran, Xiaocong Yu, Brian C. Mackness, Ekaterina Boudanova, Joern Hopke, Jose Sancho, Jacqueline Saleh, HyunSuk Cho, Ningning Zhang, Helene Simonds-Mannes, Samuel D. Stimple, Dietmar Hoffmann, Anna Park, Partha S. Chowdhury, Sambasiva P. Rao   +15 more
doaj   +1 more source

Intrathecal B-cell activation in LGI1 antibody encephalitis. [PDF]

, 2020
ObjectiveTo study intrathecal B-cell activity in leucine-rich, glioma-inactivated 1 (LGI1) antibody encephalitis. In patients with LGI1 antibodies, the lack of CSF lymphocytosis or oligoclonal bands and serum-predominant LGI1 antibodies suggests a ...
Dandekar, Ravi, Gelfand, Jeffrey M, Geschwind, Michael D, Greenfield, Ariele L, Irani, Sarosh R, Jahn, Sarah, Lehmann-Horn, Klaus, Lepennetier, Gildas, Michael, Sophia, Palanichamy, Arumugam, von Büdingen, H-Christian, Wang, Shengzhi, Wilson, Michael R, Zamvil, Scott S   +13 more
core  

Effects of antibodies against tubulin on the movement of reactivated sea urchin sperm flagella [PDF]

, 1980
Antibodies binding to sea urchin flagellar outer-doublet tubulin have been isolated from rabbit sera by tubulin-affinity chromatography employing electrophoretically purified tubulin as the immobilized substrate.
Asai, David J., Brokaw, Charles J.
core   +1 more source

The effect of Staphylococcus aureus carriage in late pregnancy on antibody levels to staphylococcal toxins in cord blood and breast milk. [PDF]

, 2008
We investigated the effect of carriage of Staphylococcus aureus in the later stages of pregnancy on levels of antibody specific to the S. aureus toxins, staphylococcal enterotoxin B (SEB), staphylococcal enterotoxin C (SEC) and toxic shock syndrome toxin-
Al Madani, Alm, Blackwell, Cui, David R. Telford, Essery, Fleming, Ford, Fujita, Gordon, Harrison, Harrison, Harrison, Holt, Hu, James A. Morris, Leach, Linda M. Harrison, Lindberg, Loch, Malam, Mathews, Molony, Morris, Morris, Murrell, Narita, Newbould, Notermans, Parsonnet, Peacock, Robert M. Lauder, Siarakas, Takahashi, Telford, Vergeront, Wilmott-Pitcher, Zorgani   +37 more
core   +1 more source

Fc-Based Recombinant Henipavirus Vaccines Elicit Broad Neutralizing Antibody Responses in Mice

Viruses, 2020
The genus Henipavirus (HNVs) includes two fatal viruses, namely Nipah virus (NiV) and Hendra virus (HeV). Since 1994, NiV and HeV have been endemic to the Asia–Pacific region and responsible for more than 600 cases of infections. Two emerging HNVs, Ghana
Yaohui Li, Ruihua Li, Meirong Wang, Yujiao Liu, Ying Yin, Xiaodong Zai, Xiaohong Song, Yi Chen, Junjie Xu, Wei Chen   +9 more
doaj   +1 more source

Complete Mapping of Mutations to the SARS-CoV-2 Spike Receptor-Binding Domain that Escape Antibody Recognition

bioRxiv, 2020
Antibodies targeting the SARS-CoV-2 spike receptor-binding domain (RBD) are being developed as therapeutics and make a major contribution to the neutralizing antibody response elicited by infection.
Allison J. Greaney, Tyler N. Starr, P. Gilchuk, Seth J. Zost, E. Binshtein, Andrea N. Loes, Sarah K. Hilton, J. Huddleston, Rachel T. Eguia, K. H. Crawford, A. Dingens, Rachel S. Nargi, Rachel E. Sutton, Naveenchandra Suryadevara, Paul W. Rothlauf, Zhuoming Liu, S. Whelan, R. Carnahan, J. Crowe, J. Bloom   +19 more
semanticscholar   +1 more source

Convalescent Plasma Antibody Levels and the Risk of Death from Covid-19

New England Journal of Medicine, 2021
Background Convalescent plasma has been widely used to treat coronavirus disease 2019 (Covid-19) under the presumption that such plasma contains potentially therapeutic antibodies to severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) that can ...
M. Joyner, R. Carter, Jonathon W. Senefeld, S. Klassen, J. Mills, Patrick W. Johnson, E. Theel, C. Wiggins, K. A. Bruno, A. Klompas, E. Lesser, K. Kunze, M. Sexton, J. D. Diaz Soto, S. Baker, J. Shepherd, N. van Helmond, N. Verdun, P. Marks, C. V. van Buskirk, J. Winters, J. Stubbs, R. Rea, D. Hodge, V. Herasevich, E. Whelan, A. Clayburn, K. Larson, J. Ripoll, K. Andersen, M. Buras, M. Vogt, J. Dennis, R. Regimbal, P. Bauer, J. Blair, N. Paneth, D. Fairweather, R. Wright, A. Casadevall   +39 more
semanticscholar   +1 more source