Results 111 to 120 of about 5,391,353 (307)
Molecular Oncology, EarlyView.LUNAR is a liver‐specific long noncoding RNA (lncRNA) that is highly expressed in normal liver but becomes epigenetically silenced in hepatocellular carcinoma through promoter hypermethylation. Loss of LUNAR is associated with NOTCH activation, epithelial–mesenchymal transition, and metastasis, whereas restoring LUNAR restrains metastatic progression ...
Se Ha Jang +9 more
wiley +1 more source
Outsmarting Pathogens with Antibody Engineering. [PDF]
Annu Rev Chem Biomol Eng, 2023 Qerqez AN, Silva RP, Maynard JA.
europepmc +1 more source
Engineering Vanderbilt; Vol. 47 No. 02, 2006
, 2006 Engineering Vanderbilt (formerly Engineering News) is the newsletter of the Vanderbilt University School of EngineeringSchool of ...
Vanderbilt University. School of Engineering
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CEACAM1 participation in breast cancer progression
Molecular Oncology, EarlyView.In invasive breast cancer (BC), CEACAM1 shifts from an apical to a uniform membranous/cytoplasmic pattern, or is lost, as tumors dedifferentiate, inversely tracking the Ki‐67 proliferative index. In MCF‐7 cells, only CEACAM1‐4L suppresses proliferation, repressing cell cycle and growth factor genes.
Mykola Lyndin +3 more
wiley +1 more source
Developing CUREs for Antibody Engineering
, 2022 In this video, published by InnovATEBIO, Sandra Porter and Sheela Vemu explore antibody engineering research projects. The video largely focuses on the results of an Antibody Engineering Hackathon, which was launched as a means to ...
Porter, Sandra (biologist), Vemu, Sheela
core +1 more source
Engineering Vanderbilt; Vol. 52, No. 01, 2011
, 2011 Engineering Vanderbilt (formerly Engineering News) is the newsletter of the Vanderbilt University School of Engineering.Vanderbilt University.
Vanderbilt University. School of Engineering
core
Pharmacological chromatin remodeling enhances response to estrogen therapy in ER+ breast cancer
Molecular Oncology, EarlyView.Estrogen therapy elicits clinical benefit in ~ 30% of patients with endocrine‐resistant estrogen receptor (ER)‐positive breast cancer. Based on findings that ER transcriptional activation underlies response to estrogen therapy, we tested the effects of epigenetic dysregulation via pharmacological inhibition of histone deacetylases (HDACi).
Anneka L. Johnson Thomas +16 more
wiley +1 more source
Simplifying complex antibody engineering using machine learning. [PDF]
Cell Syst, 2023 Makowski EK, Chen HT, Tessier PM.
europepmc +1 more source
Engineering Vanderbilt; Vol. 43 No. 02, 2002
, 2002 Engineering Vanderbilt (formerly Engineering News) is the newsletter of the Vanderbilt University School of EngineeringSchool of ...
Vanderbilt University. School of Engineering
core