A COMPARISON OF CUTANEOUS SENSITIZATION AND ANTIBODY FORMATION IN RABBITS IMMUNIZED BY INTRAVENOUS OR INTRADERMAL INJECTIONS OF INDIFFERENT OR HEMOLYTIC STREPTOCOCCI AND PNEUMOCOCCI [PDF]
, 1941 D. Murray Angevine
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Molecular Oncology, EarlyView.Loss of primary cilia in endothelial cells promotes EndMT and vascular abnormalities in the ovarian tumor microenvironment through EphA2 activation. Using human samples, in vitro models, and endothelial‐specific Kif3a‐knockout mice, we show that primary cilia loss drives the acquisition of cancer‐associated fibroblast‐like phenotypes, thereby ...
Jin Gu Cho +11 more
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Recipient priming to one RBC alloantigen directly enhances subsequent alloimmunization in mice
Blood Advances, 2018 : Individuals that become immunized to red blood cell (RBC) alloantigens can experience an increased rate of antibody formation to additional RBC alloantigens following subsequent transfusion. Despite this, how an immune response to one RBC immunogen may
Seema R. Patel +8 more
doaj
Neutralizing Antibody Formation with OnabotulinumtoxinA (BOTOX®) Treatment from Global Registration Studies across Multiple Indications: A Meta-Analysis. [PDF]
Toxins (Basel), 2023 Jankovic J +11 more
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HYPERSENSITIVENESS AND ANTIBODY FORMATION IN TUBERCULOUS RABBITS [PDF]
, 1936 Jules Freund +2 more
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Genomics‐led approach to drug testing in models of undifferentiated pleomorphic sarcoma
Molecular Oncology, EarlyView.GA text Genomic data from undifferentiated pleomorphic sarcoma patients and preclinical models were used to inform a targeted drug screen. Selected compounds were tested in 2D and 3D cultures of UPS cell lines. A combination of trametinib and infigratinib was synergistic in the majority of UPS cell lines tested, which was further confirmed in an ex ...
Piotr J. Manasterski +19 more
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A cohort study reveals different dynamics of SARS-CoV-2-specific antibody formation after Comirnaty and Vaxzevria vaccination. [PDF]
Vaccine, 2023 Augustyniak A +13 more
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Molecular Oncology, EarlyView.This study identifies nuclear YB‐1 S102 phosphorylation as a marker associated with KRAS and FBXW7 mutations in colorectal cancer. Mutated KRAS correlates specifically with nuclear, not cytoplasmic, S102 YB‐1. These findings provide the first ex vivo evidence of this link in CRC and suggest future studies should assess the prognostic and therapeutic ...
Konstanze Lettau +9 more
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THE FORMATION OF ANTIBODIES IN MAN AFTER INJECTION OF PNEUMOCOCCAL POLYSACCHARIDES [PDF]
, 1957 Michael Heidelberger
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A nucleotide‐independent, pan‐RAS‐targeted DARPin elicits anti‐tumor activity in a multimodal manner
Molecular Oncology, EarlyView.We report a Designed Ankyrin Repeat Protein that binds and inhibits RAS proteins, which serve as central cell signaling hubs and are essential for the progression of many cancers. Its unique feature is that it does not discriminate between different RAS isoforms or mutations and is capable of binding to RAS in both its active (GTP‐bound) and inactive ...
Jonas N. Kapp +13 more
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