Results 41 to 50 of about 1,551,191 (331)

Factors of Innate and Adaptive Local Immunity in Children with Primary Deficiencies of Antibody Formation

Zdorovʹe Rebenka, 2013
In 40 children with various types of primary immunodeficiencies (PID) of antibody formation we examined factors of local immunity in saliva. It is found that in the saliva of children with PID of antibody formation in comparison with immunocompetent ...
L.I. Chernyshova, S.A. Yakymovych, A.V. Chernyshov, B.V. Donskoy, L.V. Stamboli   +4 more
doaj   +3 more sources

Development, Characterization, and in vivo Validation of a Humanized C6 Monoclonal Antibody that Inhibits the Membrane Attack Complex

Journal of Innate Immunity, 2022
Damage and disease of nerves activates the complement system. We demonstrated that activation of the terminal pathway of the complement system leads to the formation of the membrane attack complex (MAC) and delays regeneration in the peripheral nervous ...
Heidi Gytz Olesen, Iliana Michailidou, Wioleta M. Zelek, Jeroen Vreijling, Patrick Ruizendaal, Ferry de Klein, J. Arnoud Marquart, Thomas B. Kuipers, Hailiang Mei, Yuchun Zhang, Muhammad Ahasan, Krista K. Johnson, Yi Wang, B. Paul Morgan, Marcus van Dijk, Kees Fluiter, Gregers Rom Andersen, Frank Baas   +17 more
doaj   +1 more source

Imunidade relacionada à resposta alérgica no início da vida Immunity related to allergic response at the beginning of life

Jornal de Pediatria, 2001
OBJETIVO: considerando-se que é na infância que as manifestações alérgicas mais comuns (asma, rinite, dermatite, alergia alimentar) ocorrem, porque é no início da vida que o sistema imune pode ser induzido à sensibilização ao invés de tolerância ...
Joaquina M.M. Correa, Antonio Zuliani
doaj   +1 more source

The tyrosine phosphatase CD148 is an essential positive regulator of platelet activation and thrombosis [PDF]

, 2009
Platelets play a fundamental role in hemostasis and thrombosis. They are also involved in pathologic conditions resulting from blocked blood vessels, including myocardial infarction and ischemic stroke.
Abtahian, Alexandra Mazharian, Arias-Salgado, Arias-Salgado, Arthur Weiss, Asselin, Auger, Avecilla, Baker, Best, Best, Cheli, Choudhuri, Dhanjal, Dorahy, Dubois, Ezumi, Gibbins, Gibbins, Harper, Hermiston, Holsinger, Jenson Lim, Jing W. Zhu, Jocelyn M. Auger, Kalia, Kato, Klages, Kovalenko, Kralisz, Kristin N. Kornerup, Le Pera, Lin, Lin, Liu, Mangin, McCarty, McNeill, Michael G. Tomlinson, Minuz, Moarefi, Mocsai, Morton, Neena Kalia, Nonne, Obergfell, Palka, Park, Pasquet, Pasquet, Pasquet, Pearce, Poole, Quek, Senis, Snell, Somani, Sorby, Steve G. Thomas, Steve P. Watson, Stuart Ellison, Superti-Furga, Suzuki-Inoue, Suzuki-Inoue, Tarvinder Dhanjal, Tsuboi, Vandendries, Wagner, Watanabe, Watson, Wonerow, Woodside, Xu, Xu, Yamaguchi, Yan Zhao, Yotis A. Senis, Young, Zhang, Zhu   +79 more
core   +2 more sources

Systemic sclerostin antibody treatment increases osseointegration and biomechanical competence of zoledronic-acid-coated dental implants in a rat osteoporosis model [PDF]

European Cells & Materials, 2019
Osseointegration of dental implants can be promoted by implant-surface modifications using bisphosphonate coatings. In addition, it is of clinical interest to promote peri-implant bone formation and to restore bony structure in low bone-mass patients ...
P Korn, I Kramer, F Schlottig, N Tödtmann, U Eckelt, A Bürki, SJ Ferguson, A Kautz, M Schnabelrauch, U Range, M Kneissel, B Stadlinger   +11 more
doaj   +1 more source

A RIAM/lamellipodin-talin-integrin complex forms the tip of sticky fingers that guide cell migration. [PDF]

, 2015
The leading edge of migrating cells contains rapidly translocating activated integrins associated with growing actin filaments that form 'sticky fingers' to sense extracellular matrix and guide cell migration.
Ablack, Jailal N, Bachir, Alexia I, Ginsberg, Mark H, Horwitz, Alan F, Lagarrigue, Frederic, Lee, Ho-Sup, Vikas Anekal, Praju   +6 more
core   +2 more sources

REGULATION OF ANTIBODY FORMATION BY SERUM ANTIBODY [PDF]

The Journal of Experimental Medicine, 1969
Rabbits were injected intravenously with bovine serum albumin (BSA) and bacteriophage T2 (T2). 2–3 wk later, anti-BSA was removed from such animals by a procedure which involved exposure of removed plasma to an immunoadsorbent (125I-BSA bound to bromoacetyl cellulose) and return of the adsorbed plasma to the animal.
Martin W. Graf, Jonathan W. Uhr
openaire   +1 more source

Cutaneous cytomegalovirus infection in a child with hyper IgE and specific defects in antibody response to protein vaccines

Brazilian Journal of Infectious Diseases
Cytomegalovirus (CMV) infection is a common opportunistic systemic infection in immunocompromised patients, but skin involvement is rare. Herein, we report a 10 year-old girl from consanguineous parents who was referred to our center because of ...
Shahrzad Fallah, Ahmad Tabatabaei, Zahra Pournasir, Zahra Chavoshzadeh, Nima Rezaei   +4 more
doaj   +1 more source

Immunological efficacy of Vaccination against Measles in Children with Down syndrome

Журнал инфектологии, 2014
The data of current vaccination process of cellular, humoral immunity and specific antibody formation in 41 children with Down syndrome at the age of 1 year to 6 years old is observed.
S. P. Kaplina, S. M. Kharit, E. I. Alexandrova   +2 more
doaj   +1 more source

Plasmodium falciparum gametogenesis essential protein 1 (GEP1) is a transmission‐blocking target

FEBS Letters, EarlyView.
This study shows Plasmodium falciparum GEP1 is vital for activating sexual stages of malarial parasites even independently of a mosquito factor. Knockout parasites completely fail gamete formation even when a phosphodiesterase inhibitor is added. Two single‐nucleotide polymorphisms (V241L and S263P) are found in 12%–20% of field samples.
Frederik Huppertz, Milagros Siebeck Caturelli, Lina S. Lehmann, Florian Kurth, Alexander G. Maier, Kai Matuschewski   +5 more
wiley   +1 more source