Results 31 to 40 of about 1,554,946 (301)

Targeting interleukin-1β protects from aortic aneurysms induced by disrupted transforming growth factor β signaling [PDF]

, 2017
Aortic aneurysms are life-threatening conditions with effective treatments mainly limited to emergency surgery or trans-arterial endovascular stent grafts, thus calling for the identification of specific molecular targets.
Bizzotto, Dario, Braghetta, Paola, Bressan, Giorgio M., Carnevale, Daniela, Carnevale, Lorenzo, Carnevale, Raimondo, Casaburo, Manuel, Cifelli, Giuseppe, DA ROS, Francesco, Fardella, Stefania, Iacobucci, Roberta, Lembo, Giuseppe, Perrotta, Marialuisa, Vinciguerra, Iolanda   +13 more
core   +1 more source

Immunological efficacy of Vaccination against Measles in Children with Down syndrome

Журнал инфектологии, 2014
The data of current vaccination process of cellular, humoral immunity and specific antibody formation in 41 children with Down syndrome at the age of 1 year to 6 years old is observed.
S. P. Kaplina, S. M. Kharit, E. I. Alexandrova   +2 more
doaj   +1 more source

Idiotype-antiidiotypic interaction of antibodies in the bloodstream [PDF]

The Ukrainian Biochemical Journal, 2014
A problem of “prozone” formation in agglutination of corpuscular antibodies by bivalent antibodies­ was considered. Using a new coordinate system, which was proposed by us earlier, we analyzed theoretical and experimental curves that describe relations ...
S. A. Bobrovnik
doaj   +1 more source

Filamin-A is required for the incorporation of tissue factor into cell-derived microvesicles [PDF]

, 2013
We previously reported that the incorporation of tissue factor (TF) into cell-derived microvesicles (MVs) is regulated by the phosphorylation of the cytoplasmic domain of TF.
Collier, Mary E. W., Ettelaie, Camille, Maraveyas, Anthony   +2 more
core   +1 more source

Factors of Innate and Adaptive Local Immunity in Children with Primary Deficiencies of Antibody Formation

Zdorovʹe Rebenka, 2013
In 40 children with various types of primary immunodeficiencies (PID) of antibody formation we examined factors of local immunity in saliva. It is found that in the saliva of children with PID of antibody formation in comparison with immunocompetent ...
L.I. Chernyshova, S.A. Yakymovych, A.V. Chernyshov, B.V. Donskoy, L.V. Stamboli   +4 more
doaj   +3 more sources

Autophagy processes are dependent on EGF receptor signaling [PDF]

, 2018
Autophagy is a not well-understood conserved mechanism activated during nutritional deprivation in order to maintain cellular homeostasis. In the present study, we investigated the correlations between autophagy, apoptosis and the MAPK pathways in ...
Capodifoglio, Sabrina, Caruso, Marika, Conti, Pio, Flati, Vincenzo, Iuliis, Vincenzo De, Lanuti, Paola, Marino, Antonio, Marricareda, Valeria, Martinotti, Stefano, Marynuk, Anna, Talora, Claudio, Toniato, Elena, Ursi, Sebastiano   +12 more
core   +1 more source

Development, Characterization, and in vivo Validation of a Humanized C6 Monoclonal Antibody that Inhibits the Membrane Attack Complex

Journal of Innate Immunity, 2022
Damage and disease of nerves activates the complement system. We demonstrated that activation of the terminal pathway of the complement system leads to the formation of the membrane attack complex (MAC) and delays regeneration in the peripheral nervous ...
Heidi Gytz Olesen, Iliana Michailidou, Wioleta M. Zelek, Jeroen Vreijling, Patrick Ruizendaal, Ferry de Klein, J. Arnoud Marquart, Thomas B. Kuipers, Hailiang Mei, Yuchun Zhang, Muhammad Ahasan, Krista K. Johnson, Yi Wang, B. Paul Morgan, Marcus van Dijk, Kees Fluiter, Gregers Rom Andersen, Frank Baas   +17 more
doaj   +1 more source

PTHrP treatment of colon cancer cells promotes tumor associated-angiogenesis by the effect of VEGF [PDF]

, 2019
We showed that Parathyroid Hormone-related Peptide (PTHrP) induces proliferation, migration, survival and chemoresistance via MAPKs and PI3K/AKT pathways in colorectal cancer (CRC) cells.
Calvo, Natalia Graciela, Carriere, Pedro Matias, Gentili, Claudia Rosana, Gigola, Graciela, Martín, María Julia   +4 more
core   +1 more source

CD44 Antibodies Inhibit Osteoclast Formation [PDF]

Journal of Bone and Mineral Research, 1997
Abstract Osteoclast differentiation is a complex process requiring multiple factors and sequential regulation. We have determined that CD44, a cell surface glycoprotein that is known to function as an adhesion receptor, is involved in this process.
J R, Kania, T, Kehat-Stadler, S R, Kupfer   +2 more
openaire   +2 more sources

Biomolecular sensing using surface micromachined silicon plates [PDF]

, 2007
Micromachined sensors to detect surface stress changes associated with interactions between an immobilized chemically selective receptor and a target analyte are presented.
Carlen, E.T., Hsiao, J., Kim, E.S., Traviglia, D., Weinberg, M.S., Zapata, A.M.   +5 more
core   +2 more sources