Results 41 to 50 of about 1,140,100 (305)
THE ABSENCE OF ANTIBODY IN THE MACROPHAGES DURING MAXIMUM ANTIBODY FORMATION [PDF]
Journal of Experimental Medicine, 1946 Following the injection of dysentery antigen in saline or in saline-in-paraffin-oil emulsion into the pad of the rabbit's hind foot, considerable quantities of antibody were recovered from the popliteal lymph node, while the tissue at the site of injection, containing many granulocytes and numerous macrophages, revealed only insignificant quantities of
W E, EHRICH, T N, HARRIS, E, MERTENS
openaire +3 more sources
Organoids in pediatric cancer research
FEBS Letters, EarlyView.Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley +1 more source
Effects of a monoclonal antibody against (pro)renin receptor on gliomagenesis
Scientific Reports, 2023 Glioblastoma is characterized by a strong self-renewal potential and poor differentiated state. We have reported previously that the (pro)renin receptor [(P)RR] is a potential target for glioma therapy by silencing the (P)RR gene.
Takeshi Fujimori +10 more
doaj +1 more source
Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation
FEBS Letters, EarlyView.Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe +3 more
wiley +1 more source
Antibody-Bridged Beacon for Homogeneous Detection of Small Molecules
, 2018 In conventional competitive immunoassays for small molecules (SM), antibodies are either immobilized to solid phases or labeled with magnetic particles or probes.
X. Chris Le (17762) +5 more
core +1 more source
Brazilian Journal of Infectious DiseasesCytomegalovirus (CMV) infection is a common opportunistic systemic infection in immunocompromised patients, but skin involvement is rare. Herein, we report a 10 year-old girl from consanguineous parents who was referred to our center because of ...
Shahrzad Fallah +4 more
doaj +1 more source
FEBS Letters, EarlyView.We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley +1 more source
eLife, 2021 Antibody production following vaccination can provide protective immunity to subsequent infection by pathogens such as influenza viruses. However, circumstances where antibody formation is impaired after vaccination, such as in older people, require us ...
Danika L Hill +12 more
doaj +1 more source
FEBS Letters, EarlyView.In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai +9 more
wiley +1 more source
A study of antibody secretion from hybridoma cells [PDF]
, 1988 The secretion of monoclonal antibody in both batch and continuous cultures was studied. It was found that when hybridoma cells were continuously cultivated in a simple lab scale fermenter, they secreted less antibody than cells grown in stationary ...
Holland, P.N.
core