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Triglyceride and Glucose Index Predicts Acute Coronary Syndrome in Patients with Antineutrophil Cytoplasmic Antibody-Associated Vasculitis [PDF]

Diagnostics, 2022
This study investigated whether the triglyceride (TG) glucose (TyG) index at diagnosis could predict acute coronary syndrome (ACS) in patients with antineutrophil cytoplasmic antibody (ANCA)-associated vasculitis (AAV).
Pil Gyu Park, Jung Yoon Pyo, Sung Soo Ahn   +2 more
exaly   +3 more sources

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Diffusion-Precipitin Index to Antibody Avidity

Science, 1961
Antigen, diffusing into converging edges of an antibody depot, inhibits the precipitation unless the reaction is completed before an inhibiting antigen excess is established. Since the rate of the increase of antigen concentration depends on the size of the angle, relative avidities of similar preparations of antibody may be estimated from the angle ...
R K, JENNINGS, M A, KAPLAN
openaire   +2 more sources

Naturally Occurring Antibodies to Phosphocholine as a Potential Index of Antibody Responsiveness to Polysaccharides

Journal of Infectious Diseases, 1987
Naturally occurring antibodies reactive with the phosphocholine (PC) determinant of pneumococcal teichoic acids may be useful for evaluating the potential of patients to make antibodies to polysaccharides. Antibodies to PC are present in most adults under the age of 60 years, are absent in very young children, and are present at low levels in Wiscott ...
D E, Briles, G, Scott, B, Gray, M J, Crain, M, Blaese, M, Nahm, V, Scott, P, Haber   +7 more
openaire   +2 more sources

Ki-67 Antibody Labeling Index in Colorectal Carcinoma

Journal of Clinical Gastroenterology, 1992
Ki-67 labeling index of 58 colorectal carcinomas and 10 normal colonic mucosa samples was determined by the use of an immunohistochemical staining technique. The Ki-67 labeling index in colorectal carcinomas ranged from 15.7 to 63.6% (mean +/- SD of 38.5 +/- 10.5) and was significantly higher than the index for normal colon mucosa (mean +/- SD of 14.1 +
H, Suzuki, K, Matsumoto, M, Terabe
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Antibody index and specific antibody quotient in horses after intragastric administration of Sarcocystis neurona sporocysts

American Journal of Veterinary Research, 2008
Abstract Objective—To investigate the use of a specific antibody index (AI) that relates Sarcocystis neurona–specific IgG quotient (QSN) to total IgG quotient (QIgG) for the detection of the anti–S neurona antibody fraction of CNS origin in CSF samples obtained from horses after intragastric administration of S neurona sporocysts.
Katherine A, Heskett, Robert J, Mackay
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Antibody efficacy as a keen index to evaluate influenza vaccine effectiveness

Vaccine, 1997
The efficacy of the influenza vaccine is often understimated, due to the dilution of the outcome by noninfluenzal illnesses. We thus explored the methodology to evaluate the effect of the inactivated influenza vaccine under the following strict conditions: an assessment of the effectiveness on clinical illness among healthy adults in a small-scale ...
Y, Hirota, M, Kaji, S, Ide, J, Kajiwara, K, Kataoka, S, Goto, T, Oka   +6 more
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Heart-Reactive Antibody: An Index of Cardiac Rejection in Human Heart Transplantation

Circulation, 1970
Indirect immunofluorescent techniques used for detection of heart-reactive antibody have been used in both human and experimental cardiac transplantation. Definite evidence is presented which demonstrates the presence of circulating heart-reactive antibody preceding clinical or laboratory evidence of cardiac rejection.
R J, Ellis, C W, Lillehei, V A, Fischetti, J B, Zabriskie   +3 more
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Site-specific conjugation of a cytotoxic drug to an antibody improves the therapeutic index

Nature Biotechnology, 2008
Antibody-drug conjugates enhance the antitumor effects of antibodies and reduce adverse systemic effects of potent cytotoxic drugs. However, conventional drug conjugation strategies yield heterogenous conjugates with relatively narrow therapeutic index (maximum tolerated dose/curative dose). Using leads from our previously described phage display-based
Jagath R, Junutula, Helga, Raab, Suzanna, Clark, Sunil, Bhakta, Douglas D, Leipold, Sylvia, Weir, Yvonne, Chen, Michelle, Simpson, Siao Ping, Tsai, Mark S, Dennis, Yanmei, Lu, Y Gloria, Meng, Carl, Ng, Jihong, Yang, Chien C, Lee, Eileen, Duenas, Jeffrey, Gorrell, Viswanatham, Katta, Amy, Kim, Kevin, McDorman, Kelly, Flagella, Rayna, Venook, Sarajane, Ross, Susan D, Spencer, Wai, Lee Wong, Henry B, Lowman, Richard, Vandlen, Mark X, Sliwkowski, Richard H, Scheller, Paul, Polakis, William, Mallet   +30 more
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Developability Index: A Rapid In Silico Tool for the Screening of Antibody Aggregation Propensity

Journal of Pharmaceutical Sciences, 2012
Determining the aggregation propensity of protein-based biotherapeutics is an important step in the drug development process. Typically, a great deal of data collected over a large period of time is needed to estimate the aggregation propensity of biotherapeutics.
Timothy M, Lauer, Neeraj J, Agrawal, Naresh, Chennamsetty, Kamal, Egodage, Bernhard, Helk, Bernhardt L, Trout   +5 more
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Terminal latency index in neuropathy with antibodies against myelin‐associated glycoproteins

Muscle & Nerve, 2007
AbstractNeuropathy with antibodies against myelin‐associated glycoproteins (MAG/SGPG‐N) and hereditary sensorimotor neuropathy type 1 (HMSN1) are characterized by chronic demyelination with little conduction block. Electrodiagnostic studies suggest that in HMSN1 conduction slowing occurs uniformly along the nerve, whereas in MAG/SGPG‐N it is ...
Vitalie D, Lupu, Carlos A, Mora, Jim, Dambrosia, Jacob, Meer, Marinos, Dalakas, Mary Kay, Floeter   +5 more
openaire   +2 more sources