Results 61 to 70 of about 2,253,953 (246)

Combined Heart and Kidney Transplantation: Clinical Experience in 100 Consecutive Patients

Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, 2019
Background Combined heart and kidney transplantation (HKTx) is performed in patients with severe heart failure and advanced renal insufficiency. We analyzed the long‐term survival after HKTx, the influence of age and dialysis status, the rates of cardiac
Morcos Atef Awad, Lawrence S. C. Czer, Dominic Emerson, Stanley Jordan, Michele A. De Robertis, James Mirocha, Evan Kransdorf, David H. Chang, Jignesh Patel, Michelle Kittleson, Danny Ramzy, Joshua S. Chung, J. Louis Cohen, Fardad Esmailian, Alfredo Trento, Jon A. Kobashigawa   +15 more
doaj   +1 more source

Animals treated with post-transplant APRIL/BLyS blockade did not develop antibody mediated rejection.

, 2019
Animals treated with post-transplant APRIL/BLyS blockade did not develop antibody mediated rejection.
Natalie M. Bath (6316517), Arjang Djamali (6316535), Brittney A. Boldt (6316523), Sarah E. Panzer (6316532), Robert R. Redfield III (6316538), Xiang Ding (607469), Adarsh Sukhwal (6316526), Shannon R. Reese (6316529), Nancy A. Wilson (36137), Bret M. Verhoven (6316520)   +9 more
core   +1 more source

Histopathologic insights into the mechanism of anti-non-Gal antibody-mediated pig cardiac xenograft rejection. [PDF]

, 2013
The histopathology of cardiac xenograft rejection has evolved over the last 20 yr with the development of new modalities for limiting antibody-mediated injury, advancing regimens for immune suppression, and an ever-widening variety of new donor genetics.
Tazelaar, HD, Cooper, DK, Burcin Ekser, Byrne, GW, Guerard W. Byrne, Simon C. Robson, Azimzadeh, AM, David K. C. Cooper, Pierson, RN, McGregor, CG, Christopher G. A. McGregor, Robson, SC, Richard N. Pierson, Agnes M. Azimzadeh, Mohamed Ezzelarab, Ekser, B, Ezzelarab, M, Henry D. Tazelaar   +17 more
core   +1 more source

Intrasplenic Thymus Organogenesis from Injectable Tissue Fragments Restores Functional T‐Cell Immunity

Advanced Science, EarlyView.
Clinical intramuscular thymus transplantation yields only short‐lived efficacy and marginal therapeutic benefits. Benefiting from the spleen's intrinsic strengths—rapid vascular perfusion, abundant developmental factors, and resident progenitors—the intrasplenic thymic grafts achieve robust thymic regeneration and substantial T‐cell reconstitution ...
Shaocong Wang, Zijian Zhang, Fulin Dai, Zhijie Yin, Zhen Xing, Yurong Li, Haochong Lei, Junfeng Zhang, Chunyan Liu, Yan Li, Lei Dong   +10 more
wiley   +1 more source

The Importance of C4d in Biopsies of Kidney Transplant Recipients

Clinical and Developmental Immunology, 2013
Antibody-mediated rejection (AMR) is highly detrimental to the prolonged survival of transplanted kidneys. C4d has been regarded as a footprint of AMR tissue damage, and the introduction of C4d staining in daily clinical practice aroused an ever ...
Rosana Rosa Miranda Corrêa, Juliana Reis Machado, Marcos Vinícius da Silva, Fernanda Rodrigues Helmo, Camila Souza Oliveira Guimarães, Laura Penna Rocha, Ana Carolina Guimarães Faleiros, Marlene Antônia dos Reis   +7 more
doaj   +1 more source

Clinical Significances of Anti-Collagen Type I and Type III Antibodies in Antibody-Mediated Rejection

, 2022
It is important to determine the clinical significance of non-human leukocyte antigen (HLA) antibodies and their association with antibody-mediated rejection (ABMR) of kidney allografts.
Park, Sehoon, Jeong, Chang Wook, Kim, Yon Su, Kim, Dong Ki, Song, Eun Young, Moon, Kyung Chul, Yang, Seung-Hee, Yang, Jaeseok, Kim, Jiyeon, Bhoo, Seong Hee, Ha, Jongwon, Oh, Kook-Hwan, Kim, Yong Chul, Lee, Hajeong, Cho, Semin, Joo, Kwon Wook, Min, Sang-Il   +16 more
core   +1 more source

Potential of Nanoparticle‐Based Phototherapies for Future Treatment of Uveal Melanoma

Advanced Science, EarlyView.
This review evaluates nanoparticle‐based phototherapies for uveal melanoma, highlighting emerging strategies to enhance tumor targeting, light delivery, and treatment precision. Preclinical data indicate improved efficacy and reduced toxicity, supporting their potential to enhance localized treatment and future translational advances. (Generated by the
Emilie Lambert, Christophe Nguyen, Sean Edward Dunn, Magali Gary‐Bobo, Jérôme Lacombe, Justin Moser, Frédéric Zenhausern, Jean‐Olivier Durand, Frédérique Cunin   +8 more
wiley   +1 more source

Quilty Lesions in the Endomyocardial Biopsies after Heart Transplantation [PDF]

Journal of Pathology and Translational Medicine, 2019
Background The aim of this study was to investigate the clinical significance of Quilty lesions in endomyocardial biopsies (EMBs) of cardiac transplantation patients.
Haeyon Cho, Jin-Oh Choi, Eun-Seok Jeon, Jung-Sun Kim   +3 more
doaj   +1 more source

Antibody-mediated lung transplant rejection [PDF]

Current Respiratory Care Reports, 2012
Antibody-mediated rejection after lung transplantation remains enigmatic. However, emerging evidence over the past several years suggests that humoral immunity plays an important role in allograft rejection. Indeed, the development of donor-specific antibodies after transplantation has been identified as an independent risk factor for acute cellular ...
openaire   +2 more sources

Mesenchymal Stromal Cell‐Based Cell–Drug Conjugates for the Treatment of Acute Liver Failure

Advanced Science, EarlyView.
Mesenchymal stromal cell (MSC)‐based cell‐drug conjugates are constructed by anchoring rosiglitazone‐loaded nanoparticles onto the MSC surface. Sustained rosiglitazone release enhances MSC proliferation and paracrine activity while promoting anti‐inflammatory macrophage polarization.
Tenghui Ye, Jiamin Wu, Zixin Wu, Xi Liu, Jiajia Luo, Leyi Yang, Peng Shi   +6 more
wiley   +1 more source