Immunochemical analysis of illegal steroid growth promoters in cattle [PDF]
, 2002 Steroid hormones and their analogues can be used as growth promoters in cattle. The use of these substances is banned in the EU, and hence each member state must ensure that cattle are not being dosed with these drugs.
Fitzpatrick, Jane
core
Humanized immune system animal models and their recent applications
Animal Models and Experimental Medicine, EarlyView.In this review, we provide an updated and comprehensive overview of the current state of humanized immune system animal model research. We discuss the variety of techniques used to produce humanized mice with their respective strengths and weaknesses, and evaluate the advantages and limitations of these models, including issues with incomplete immune ...
Nicolas Skuli +6 more
wiley +1 more source
Engraftment of sheep splenic lymphocytes into NBSGW mice and application in Brucella infection
Animal Models and Experimental Medicine, EarlyView.A sheep splenocyte‐reconstituted mouse model (Sh‐Spl mice) was established via intravenous injection of sheep splenic lymphocytes into immunodeficient mice to evaluate Brucella infection. Abstract Background The development of immune reconstituted xenograft mouse models has addressed the limitations imposed by interspecies immunological differences in ...
Xiaowei Wang +9 more
wiley +1 more source
On the analysis of antibody repertoires
, 2023 The antibody repertoire is the ensemble of antibodies found in an individual at a given time. It displays high heterogeneity between individuals while being both largely temporally stable within an individual and rapidly responsive to immunological challenge.
openaire +1 more source
Advances and perspectives in animal models of human hepatitis A virus
Animal Models and Experimental Medicine, EarlyView.Following HAV infection, humans, non‐human primates, and Ifnar1−/− mice develop characteristic manifestations of hepatitis A, including fecal viral shedding, elevated serum ALT levels, and inflammatory cell infiltration in the liver. In contrast, HAV‐infected human liver chimeric mice exhibit fecal viral shedding but do not develop clinical features of
Jian Li +3 more
wiley +1 more source
Annals of Neurology, EarlyView.Objective Multiple sclerosis (MS) is a chronic autoimmune disease where B cells play a central pathogenic role. Cladribine, an oral therapy, provides durable benefits by reshaping lymphocyte populations, yet its specific long‐term impact on distinct B‐cell subsets is not fully understood.
Marta Pirronello +20 more
wiley +1 more source
Broad responses to chemical adducts shape the natural antibody repertoire in early infancy. [PDF]
Sci Adv, 2023 Mashiko S +7 more
europepmc +1 more source
Cold Gas Plasma Induces Platelet Activation and Hemostasis in Native and Anticoagulated Human Blood
Advanced NanoBiomed Research, EarlyView.Cold physical gas plasma induces platelet activation and hemostatic responses in native and anticoagulated human blood. Treatment efficacy depends on plasma parameters, including gas composition, distance, and exposure mode, which govern reactive species delivery and energy transfer.
Sander Bekeschus +5 more
wiley +1 more source
Epitope-level profiling in children with mitochondrial disease reveals limitations in the antibacterial antibody repertoire. [PDF]
Mol Genet Metab, 2023 Gordon-Lipkin EM +5 more
europepmc +1 more source
Exploring the human genomic DNA antibody repertoire for development of an effective HIV-1 vaccine
, 2014 HIV-1 broadly neutralizing antibodies (bnAbs) with great potency and breadth have been identified from approximately 10 to 30% HIV-1 infected individuals with protection against viral infections in vitro and in vivo.
Zhang, Yu, 張宇
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