Results 1 to 10 of about 106,980 (248)
NAIR: Network Analysis of Immune Repertoire [PDF]
Frontiers in Immunology, 2023 T cells represent a crucial component of the adaptive immune system and mediate anti-tumoral immunity as well as protection against infections, including respiratory viruses such as SARS-CoV-2.
Hai Yang +8 more
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Transcriptomic Insights Into the Immune Repertoire of an Antarctic Sponge [PDF]
Ecology and EvolutionAntarctic marine sponges are essential components of the benthic fauna, playing a crucial role both through their own biological activities and their symbiotic relationships with diverse microorganisms.
Leslie K. Daille +3 more
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Immune repertoire profiling for disease pathobiology [PDF]
Pathology International, 2023 AbstractLymphocytes consist of highly heterogeneous populations, each expressing a specific cell surface receptor corresponding to a particular antigen. Lymphocytes are both the cause and regulator of various diseases, including autoimmune/allergic diseases, lifestyle diseases, neurodegenerative diseases, and cancers.
Hiroto Katoh +2 more
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Immune fingerprinting through repertoire similarity. [PDF]
PLoS Genetics, 2021 Immune repertoires provide a unique fingerprint reflecting the immune history of individuals, with potential applications in precision medicine. However, the question of how personal that information is and how it can be used to identify individuals has ...
Thomas Dupic +5 more
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Simultaneous profiling of the blood and gut T and B cell repertoires in Crohn’s disease and symptomatic controls illustrates tissue-specific alterations in the immune repertoire of individuals with Crohn’s disease [PDF]
Frontiers in ImmunologyIntroductionCrohn’s disease (CD) is a clinical subset of inflammatory bowel disease that is characterized by patchy transmural inflammation across the gastrointestinal tract. Although the exact etiology remains unknown, recent findings suggest that it is
Aya K. H. Mahdy +24 more
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Frontiers in Immunology, 2018 BackgroundRecent technological advances in immune repertoire sequencing have created tremendous potential for advancing our understanding of adaptive immune response dynamics in various states of health and disease.
Scott Christley +19 more
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History, applications, and challenges of immune repertoire research [PDF]
Cell Biology and Toxicology, 2018 The diversity of T and B cells in terms of their receptor sequences is huge in the vertebrate's immune system and provides broad protection against the vast diversity of pathogens. Immune repertoire is defined as the sum of T cell receptors and B cell receptors (also named immunoglobulin) that makes the organism's adaptive immune system.
Xiao Liu, Jinghua Wu, Wu Jinghua
exaly +3 more sources
Clinical application of immune repertoire sequencing in solid organ transplant [PDF]
Frontiers in Immunology, 2023 BackgroundMeasurement of T cell receptor (TCR) or B cell receptor (BCR) gene utilization may be valuable in monitoring the dynamic changes in donor-reactive clonal populations following transplantation and enabling adjustment in therapy to avoid the ...
Paaksum Wong +12 more
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crocketa: an automated Snakemake framework for integrated single-cell transcriptome and immune-repertoire analysis [PDF]
BMC Genomicscrocketa (single-Cell Repertoire Organization & Combined Kinetics Exploration for Transcriptomic Analysis) is an automated and adaptable Snakemake pipeline designed to perform fundamental initial stages of single-cell analysis for both transcriptomic and
Gonzalo Soria-Alcaide +8 more
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Polymorphic Immune Mechanisms Regulate Commensal Repertoire [PDF]
Cell Reports, 2019 Summary: Environmental influences (infections and diet) strongly affect a host’s microbiota. However, host genetics may influence commensal communities, as suggested by the greater similarity between the microbiomes of identical twins compared to non ...
Aly A. Khan +7 more
doaj +3 more sources