Ebola vaccine-induced protection in nonhuman primates correlates with antibody specificity and Fc-mediated effects. [PDF]
Meyer M +20 more
europepmc +1 more source
Field Effect Transistor Nanosensor for Breast Cancer Diagnostics [PDF]
Silicon nanochannel field effect transistor (FET) biosensors are one of the most promising technologies in the development of highly sensitive and label-free analyte detection for cancer diagnostics. With their exceptional electrical properties and small
Chen, Yu +6 more
core
Subtyping of human immunodeficiency virus type 1 strains by using antibodies specific for the third variable domain (V3) of gp120: results may be affected by divergent V3 sequences [PDF]
Kedir Sherefa +4 more
openalex +1 more source
Internalization of Foldamer-Based DNA Mimics through a Site-Specific Antibody Conjugate to Target HER2-Positive Cancer Cells [PDF]
Valentina Corvaglia +10 more
openalex +1 more source
Generation of two normal and tumour (cancerous) paired human cell lines using an established tissue culture technique and their characterisation is described. Cell lines were characterised at cellular, protein, chromosome and gene expression levels and for HPV status.
Simon Broad +12 more
wiley +1 more source
Strength through diversity: how cancers thrive when clones cooperate
Intratumor heterogeneity can offer direct benefits to the tumor through cooperation between different clones. In this review, Kuiken et al. discuss existing evidence for clonal cooperativity to identify overarching principles, and highlight how novel technological developments could address remaining open questions.
Marije C. Kuiken +3 more
wiley +1 more source
Single-antibody mutational scanning reveals poly-specificity and immune constraints in vaccination responses [PDF]
Luca Johannes Schlotheuber +5 more
openalex +1 more source
The crystal structure of a common allergen in complex with its specific patient-derived antibody [PDF]
Alkistis Mitropoulou +8 more
openalex +1 more source
Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice +16 more
wiley +1 more source

