Results 151 to 160 of about 10,170,244 (414)

Importance of establishing antibody specificity in multisystem inflammatory syndrome in newborn during the COVID-19 pandemic. [PDF]

Acta Paediatr, 2023
Leslie AT, Saleh M, Soni N, Tang P, Kallem V, Tscherning C, More K.   +6 more
europepmc   +1 more source

Protein-environment-sensitive computational epitope accessibility analysis from antibody dose-response data [PDF]

arXiv
Antibodies are widely used in life-sciences and medical therapy. Yet, broadly applicable methods are missing to determine, in the biological system of choice, antibody specificity and its quantitative contribution to e.g. immunofluorescence stainings. Thereby, antibody-based data often needs to be seen with caution.
arxiv  

A Novel Sensitive Immunoassay Targeting the 5-Methylthio-d-Xylofuranose-Lipoarabinomannan Epitope Meets the WHO's Performance Target for Tuberculosis Diagnosis. [PDF]

, 2018
The only currently commercialized point-of-care assay for tuberculosis (TB) that measures lipoarabinomannan (LAM) in urine (Alere LF-LAM) has insufficient sensitivity.
Broger, Tobias, Choudhary, Alok, Denkinger, Claudia M, Honnen, William J, Katsuragi, Kiyonori, Kawasaki, Masanori, Li, Andra, Lowary, Todd L, Mathew, Anu, Nahid, Payam, Pinter, Abraham, Plisova, Tatiana, Shen, Ke, Sigal, George B, Tsionsky, Michael, Zheng, Ruixiang Blake   +15 more
core  

The Specific Groups of Antibodies [PDF]

, 1942
Felix Haurowitz, Muzaffer Vardar, Paula Schwerin   +2 more
openalex   +1 more source

The accumulation of myeloid‐derived suppressor cells participates in abdominal infection‐induced tumor progression through the PD‐L1/PD‐1 axis

Molecular Oncology, EarlyView.
This study explores how sepsis affects GC progression by creating an immunosuppressive environment. Our findings reveal that sepsis promotes immune dysregulation, enhancing tumor growth and metastasis. Targeting the PD‐1/PD‐L1 pathway with monoclonal antibodies shows potential for restoring immune function and improving outcomes in cancer patients ...
Yiding Wang, Ting Guo, Xiaofang Xing, Xijuan Liu, Xuejun Gan, Yingai Li, Yan Liu, Fei Shan, Zhouqiao Wu, Jiafu Ji, Ziyu Li   +10 more
wiley   +1 more source

From antibody specificity to T cell recognition. [PDF]

J Exp Med, 2021
Kim HJ, Cantor H.
europepmc   +1 more source

Efficient Antibody Structure Refinement Using Energy-Guided SE(3) Flow Matching [PDF]

arXiv
Antibodies are proteins produced by the immune system that recognize and bind to specific antigens, and their 3D structures are crucial for understanding their binding mechanism and designing therapeutic interventions. The specificity of antibody-antigen binding predominantly depends on the complementarity-determining regions (CDR) within antibodies ...
arxiv  

The PTTG1/VASP axis promotes oral squamous cell carcinoma metastasis by modulating focal adhesion and actin filaments

Molecular Oncology, EarlyView.
VASP was found to be overexpressed in metastatic oral squamous cell carcinoma (OSCC) tissues. Notably, PTTG1‐ and VASP‐deficient OSCC cells demonstrated suppressed metastatic properties by disrupting the interaction between the cytoskeleton and focal adhesion (FAs) in the filopodia region.
Suyeon Park, Sang Shin Lee, Shihyun Kim, Yeonjun Lee, Gyeonwon Park, Jung Oh Kim, Jongho Choi   +6 more
wiley   +1 more source

Clathrin structure characterized with monoclonal antibodies. I. Analysis of multiple antigenic sites. [PDF]

, 1985
Three monoclonal antibodies that react with previously undefined antigenic determinants on the clathrin molecule have been produced and characterized. They were isolated from a fusion between myeloma cells and popliteal lymphocytes from SJL mice that had
Brodsky, Frances
core  

The Influence of Non-Specific Protein on the Heat Inactivation of Antibody to Pneumococcal Polysaccharide [PDF]

, 1942
Robert K. Jennings, Louis DeSpain Smith
openalex   +1 more source