Results 191 to 200 of about 10,170,244 (414)

Digoxin-specific antibodies. [PDF]

Proceedings of the National Academy of Sciences, 1967
James Chen, Vincent P. Butler
openaire   +3 more sources

VELOCITY OF COMBINATION OF ANTIBODY WITH SPECIFIC POLYSACCHARIDES OF PNEUMOCOCCUS

, 1942
Manfred M. Mayer, Michael Heidelberger
openalex   +1 more source

Respiratory complex I‐mediated NAD+ regeneration regulates cancer cell proliferation through the transcriptional and translational control of p21Cip1 expression by SIRT3 and SIRT7

Molecular Oncology, EarlyView.
NAD+ regeneration by mitochondrial complex I NADH dehydrogenase is important for cancer cell proliferation. Specifically, NAD+ is necessary for the activities of NAD+‐dependent deacetylases SIRT3 and SIRT7, which suppress the expression of p21Cip1 cyclin‐dependent kinase inhibitor, an antiproliferative molecule, at the translational and transcriptional
Masato Higurashi, Kazunori Mori, Hidetsugu Nakagawa, Momoko Uchida, Fumihiro Ishikawa, Motoko Shibanuma   +5 more
wiley   +1 more source

Antigen-Specific Antibody Design via Direct Energy-based Preference Optimization [PDF]

arXiv
Antibody design, a crucial task with significant implications across various disciplines such as therapeutics and biology, presents considerable challenges due to its intricate nature. In this paper, we tackle antigen-specific antibody sequence-structure co-design as an optimization problem towards specific preferences, considering both rationality and
arxiv  

Immune lysis of normal human and paroxysmal nocturnal hemoglobinuria (PNH) red blood cells. I. The sensitivity of PNH red cells to lysis by complement and specific antibody. [PDF]

, 1966
WF Rosse, J. V. Dacie
openalex   +1 more source

Peripheral blood leukocyte signatures as biomarkers in relapsed ovarian cancer patients receiving combined anti‐CD73/anti‐PD‐L1 immunotherapy in arm A of the NSGO‐OV‐UMB1/ENGOT‐OV30 trial

Molecular Oncology, EarlyView.
Using mass cytometry, we analyzed serial blood samples from patients with relapsed epithelial ovarian cancer (EOC) treated with oleclumab–durvalumab combination immunotherapy in the NSGO‐OV‐UMB1/ENGOT‐OV30 trial. Our analysis identified potential predictive, monitoring, and response biomarkers detectable through liquid biopsy. These findings facilitate
Luka Tandaric, Annika Auranen, Katrin Kleinmanns, René DePont Christensen, Liv Cecilie Vestrheim Thomsen, Cara Ellen Wogsland, Emmet McCormack, Johanna Mäenpää, Kristine Madsen, Karen Stampe Petersson, Mansoor Raza Mirza, Line Bjørge   +11 more
wiley   +1 more source

Computationally Guided Design of Single-Chain Variable Fragment Improves Specificity of Chimeric Antigen Receptors

Molecular Therapy: Oncolytics, 2019
Chimeric antigen receptor (CAR)-T cell-based immunotherapy of malignant disease relies on the specificity and association constant of single-chain variable fragments (scFvs).
Andrey Krokhotin, Hongwei Du, Koichi Hirabayashi, Konstantin Popov, Tomohiro Kurokawa, Xinhui Wan, Soldano Ferrone, Gianpietro Dotti, Nikolay V. Dokholyan   +8 more
doaj  

Clinical significance of establishing a red blood cell alloantibody detection database

Zhongguo shuxue zazhi
[Objective] To explore the clinical significance and application value of establishing a database for red blood cell alloantibody detection. [Methods] Patients who were scheduled for blood transfusion in our hospital from January 1, 2020 to May 1, 2024 ...
XIAO Xiao, CHEN Long, ZHAO Zhenyu, HE Zhanghan, ZHOU Mengjun, TANG Jie   +5 more
doaj   +1 more source

Tumor Induction by SE Polyoma Virus and the Inhibition of Tumors by Specific Neutralizing Antibodies

, 1959
Sarah E. Stewart, Bernice E. Eddy
openalex   +2 more sources

Separation of antigens by immunological specificity. Use of disulphide-linked antibodies as immunosorbents [PDF]

, 1966
J. Stephen, R. G. C. Gallop, Harry Smith
openalex   +1 more source