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Apoptosis: A Target for Anticancer Therapy [PDF]
International Journal of Molecular Sciences, 2018 Apoptosis, the cell’s natural mechanism for death, is a promising target for anticancer therapy. Both the intrinsic and extrinsic pathways use caspases to carry out apoptosis through the cleavage of hundreds of proteins. In cancer, the apoptotic pathway is typically inhibited through a wide variety of means including overexpression of antiapoptotic ...
Pfeffer, Claire M. +1 more
exaly +4 more sources
PP2A-Mediated Anticancer Therapy [PDF]
Gastroenterology Research and Practice, 2013 PP2A is a family of mammalian serine/threonine phosphatases that is involved in the control of many cellular functions including protein synthesis, cellular signaling, cell cycle determination, apoptosis, metabolism, and stress responses through the ...
Weibo Chen +3 more
doaj +3 more sources
Microfluidic-Assisted Human Cancer Cells Culturing Platform for Space Biology Applications
Sensors, 2022 In the paper, the lab-on-chip platform applicable for the long-term cultivation of human cancer cells, as a solution meeting the demands of the CubeSat biological missions, is presented.
Agnieszka Krakos (Podwin) +9 more
doaj +1 more source
Combined Therapy with microRNA-Expressing Salmonella and Irradiation in Melanoma
Microorganisms, 2021 Anticancer treatment strategies using bacteria as a vector are currently expanding with the development of anticancer drugs. Here, we present a research strategy to develop anticancer drugs using bacteria that contain miRNAs.
Wonsuck Yoon +4 more
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PPARs and Anticancer Therapies [PDF]
PPAR Research, 2010 Welcome to this special issue of PPAR research, PPARs, and anticancer therapies. Peroxisomal proliferator-activated receptor (PPAR) α, δ, and γ are members of the nuclear hormone receptor superfamily of ligand-activated transcription factors first identified some 20 years ago.
Michael E. C. Robbins +2 more
openaire +3 more sources
Circulation of Fluorescently Labelled Phage in a Murine Model
Viruses, 2021 Interactions between bacteriophages and mammals strongly affect possible applications of bacteriophages. This has created a need for tools that facilitate studies of phage circulation and deposition in tissues.
Zuzanna Kaźmierczak +4 more
doaj +1 more source
JCO Global Oncology, 2022 PURPOSEIn patients with cancer, aggressive treatment near the end of life (EOL) may decrease quality of life and increase medical costs. In this study, we examined the use of anticancer therapies near the EOL in Japan.METHODSWe used a commercial database
Yusuke Kajimoto +5 more
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Molecules, 2020 A three-component reaction between diamines (diaminobenzenes, diaminocyclohexanes, and piperazines), triethyl orthoformate, and diethyl phosphite was studied in some detail.
Patrycja Petruczynik +6 more
doaj +1 more source
Beneficial Effects of Polysaccharides on the Epithelial Barrier Function in Intestinal Mucositis
Frontiers in Physiology, 2021 Intestinal mucositis is a clinically relevant side effect of anticancer therapies. It is experienced by 60–100% of patients undergoing treatment with high doses of chemotherapy, radiation therapy, and bone marrow transplantation. Intestinal mucositis can
Karien Sauruk da Silva +13 more
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The influence of acupuncture TENS currents on the proliferation of cancer cells tested in vitro
Rehabilitacja Medyczna, 2019 Introduction: Transcutaneous Electrical Nerve Stimulation (TENS) is a very popular, non-pharmacological antianalgetic method. Nonetheless, knowledge on using this method is very limited in the treatment of patients with cancer anamnesis.
Marzena Pełczyńska +3 more
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