Results 11 to 20 of about 398,610 (305)

PP2A-Mediated Anticancer Therapy [PDF]

open access: yesGastroenterology Research and Practice, 2013
PP2A is a family of mammalian serine/threonine phosphatases that is involved in the control of many cellular functions including protein synthesis, cellular signaling, cell cycle determination, apoptosis, metabolism, and stress responses through the ...
Weibo Chen   +3 more
doaj   +3 more sources

PPARs and Anticancer Therapies [PDF]

open access: yesPPAR Research, 2010
Welcome to this special issue of PPAR research, PPARs, and anticancer therapies. Peroxisomal proliferator-activated receptor (PPAR) α, δ, and γ are members of the nuclear hormone receptor superfamily of ligand-activated transcription factors first identified some 20 years ago.
Michael E. C. Robbins   +2 more
openaire   +3 more sources

The influence of acupuncture TENS currents on the proliferation of cancer cells tested in vitro

open access: yesRehabilitacja Medyczna, 2019
Introduction: Transcutaneous Electrical Nerve Stimulation (TENS) is a very popular, non-pharmacological antianalgetic method. Nonetheless, knowledge on using this method is very limited in the treatment of patients with cancer anamnesis.
Marzena Pełczyńska   +3 more
doaj   +1 more source

First-in-Class, Thiosemicarbazide-Based, Dual Inhibitors of Human DNA Topoisomerase IIα and Indoleamine-2,3-Dioxygenase 1 (IDO-1) with Strong Anticancer Properties

open access: yesMedical Sciences Forum, 2022
According to a WHO report from 2020, cancer constitutes one of the leading causes of death worldwide. The number of cancer deaths is estimated to be approximately 10 million per year.
Barbara Kaproń, Tomasz Plech
doaj   +1 more source

The natural dietary genistein boosts bacteriophage-mediated cancer cell killing by improving phage-targeted tumor cell transduction [PDF]

open access: yes, 2016
Gene therapy has long been regarded as a promising treatment for cancer. However, cancer gene therapy is still facing the challenge of targeting gene delivery vectors specifically to tumors when administered via clinically acceptable non-invasive ...
Albahrani, M   +5 more
core   +2 more sources

Anticancer Therapy and Mortality of Adult Patients with Hematologic Malignancy and COVID-19: A Systematic Review and Meta-Analysis

open access: yesLife, 2023
Coronavirus disease 2019 (COVID-19) might affect cancer treatment outcomes. This systematic review and meta-analysis identified the prognostic predictors of adult patients with hematologic malignancies and COVID-19, and evaluated the effect of anticancer
Wen-Li Lin   +4 more
doaj   +1 more source

Advances in the design and development of oncolytic measles viruses. [PDF]

open access: yes, 2015
A successful oncolytic virus is one that selectively propagates and destroys cancerous tissue without causing excessive damage to the normal surrounding tissue. Oncolytic measles virus (MV) is one such virus that exhibits this characteristic and thus has
Hutzen, Brian   +2 more
core   +1 more source

Combination treatment with recombinant methioninase enables temozolomide to arrest a BRAF V600E melanoma in a patient-derived orthotopic xenograft (PDOX) mouse model. [PDF]

open access: yes, 2017
An excessive requirement for methionine termed methionine dependence, appears to be a general metabolic defect in cancer. We have previously shown that cancer-cell growth can be selectively arrested by methionine deprivation such as with recombinant ...
Chmielowski, Bartosz   +15 more
core   +2 more sources

Emerging role of different DNA methyltransferases in the pathogenesis of cancer

open access: yesFrontiers in Pharmacology, 2022
DNA methylation is one of the most essential epigenetic mechanisms to regulate gene expression. DNA methyltransferases (DNMTs) play a vital role in DNA methylation in the genome.
Pengcheng Liu   +8 more
doaj   +1 more source

Zinc Oxide Nanocrystals and High-Energy Shock Waves: A New Synergy for the Treatment of Cancer Cells

open access: yesFrontiers in Bioengineering and Biotechnology, 2020
In the last years, different nanotools have been developed to fight cancer cells. They could be administered alone, exploiting their intrinsic toxicity, or remotely activated to achieve cell death.
Luisa Racca   +8 more
doaj   +1 more source

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