Results 61 to 70 of about 16,495 (210)

NARFL Knockout Triggers Ferroptosis‐Driven Vascular Endothelial Dysfunction

Advanced Science, Volume 13, Issue 8, 9 February 2026.
NARFL is vital for CIA and oxidative stress resistance. NARFL deletion in HPMEC cells, zebrafish, and mice is lethal and rescued by a Ferroptosis inhibitor. NARFL deficiency disrupted its interaction with CIA proteins, decreased aconitase activity, increased IRP1 activity, induced Fe overload, and led to ferroptosis and oxidative stress, resulting in ...
Hui Hu, Jing Luo, Li Yu, Daoxi Qi, Boyu Li, Yating Chen, Chen Wang, Xiaokang Zhang, Wenzheng Guo, Qiyong Lou, Gang Zhai, Yonglin Ruan, Jianfei Huang, Shengchi Shi, Zhan Yin, Fang Zheng   +15 more
wiley   +1 more source

POTS and Antiphospholipid Syndrome: An Unlikely Association

Case Reports in Rheumatology, 2021
Antiphospholipid syndrome is a rare complication of postural orthostatic tachycardia syndrome. Clinically, the presentation has overlapping symptoms of both diseases, with lightheadedness or syncope when moving from a supine to a standing position as ...
Kalvin Zee, Shakaib Qureshi
doaj   +1 more source

Prognostic Value of Lupus Anticoagulant and Anti–β2 Glycoprotein I Antibody in Adverse Pregnancy Outcomes

Arthritis &Rheumatology, Volume 78, Issue 2, Page 371-384, February 2026.
Objective International criteria for antiphospholipid syndrome (APS) include lupus anticoagulant (LA), anticardiolipin (aCL) IgG and IgM, and anti–β2‐glycoprotein I (β2GPI) IgG and IgM. However, evidence supporting their prognostic value or treatment efficacy in improving live birth rates is limited.
Megumi Nonobe, Takahiro Otani, Hiroyuki Yoshihara, Shinobu Goto, Tamao Kitaori, Naomi Nishikawa, Yuichiro Fujieda, Tatsuya Atsumi, Mayumi Sugiura‐Ogasawara   +8 more
wiley   +1 more source

Anticardiolipin antibodies in Jamaican primiparae

Journal of Obstetrics and Gynaecology, 2006
A prevalence survey of anticardiolipin antibodies (aCL) was done among 924 primiparae. aCL were measured in serum by the standardised anticardiolipin enzyme linked immunosorbent assays (ELISA) and beta(2)-glycoprotein 1 assays to determine the seroprevalence of both beta(2) glycoprotein 1 dependent aCL and beta(2)-glycoprotein 1 independent aCL in ...
E K, Kahwa, L A, Sargeant, A, McCaw-Binns, N, McFarlane-Anderson, M, Smikle, T, Forrester, R, Wilks   +6 more
openaire   +2 more sources

Resistant arterial hypertension in a patient with adrenal incidentaloma multiple steno-obstructive vascular lesions and antiphospholipid syndrome [PDF]

, 2015
Resistant hypertension is defined as above of blood pressure (≤ 140/90 mmHg) despite therapy with three or more antihypertensive drugs of different classes at maximum tolerable doses with one bling a diuretic.
CONCISTRE, ANTONIO, Gambale, G., IANNUCCI, Gino, Letizia, C., MARINELLI, CRISTIANO, PETRAMALA, LUIGI, Toma, G. De, Vincentis, G. De, ZACCARIA, Alvaro   +8 more
core  

Deep capillary retinal ischemia and high-titer prothrombin-associated antiphospholipid antibodies: A case series of three patients

American Journal of Ophthalmology Case Reports, 2019
Purpose: Acute macular neuroretinopathy has been shown to be due to ischemia of the deep capillary retinal plexus and most cases occur in young women; we hypothesized that there may be an association with antiphospholipid antibodies.
Jill R. Schofield, Alan G. Palestine, Victoria Pelak, Marc T. Mathias   +3 more
doaj   +1 more source

Antibodies to endothelial cells in Behçet's disease: cell-binding heterogeneity and association with clinical activity [PDF]

, 1994
OBJECTIVES--To investigate the prevalence and characteristics of antibodies to endothelial cells (aEC) from large vessel and from microvasculature in a group of patients with Behçet's disease (BD) to determine the relationship of these antibodies with ...
Cervera i Segura, Ricard, 1960-, Cid Xutglà, M. Cinta, Esparza Sánchez, Jordi, Font Franco, Josep, 1953-2006, Ingelmo Morín, Miguel, López-Soto, Alfonso, Monteagudo Terres, Juan, Navarro López, Margarita, Reverter Calatayud, Juan Carlos, Urbano Márquez, A. (Álvaro)   +9 more
core   +2 more sources

Laboratory Identification of Lupus Anticoagulant (LA) Using Different Activated Partial Thromboplastin Time (APTT) Assays

International Journal of Laboratory Hematology, Volume 48, Issue 1, Page 172-178, February 2026.
ABSTRACT Introduction The International Society of Thrombosis and Hemostasis (ISTH) guidelines suggest a three‐step evaluation for the detection of lupus anticoagulant (LA), including screening, mixing, and confirmation. According to the guidelines, the LA assay based on activated partial thromboplastin time (APTT) should include an initial screening ...
Bárbara G. Barion, Bianca Stefanello, Maria Luiza S. A. de Paula, Thaís S. Saraiva, Paula R. Villaça, Vanderson Rocha, Fernanda A. Orsi, Tania R. F. da Rocha   +7 more
wiley   +1 more source

Detection of anti-cardiolipin and anti-β2glycoprotein I antibodies differs between platforms without influence on association with clinical symptoms [PDF]

, 2019
Background: The anti-phospholipid syndrome (APS) is characterized by thrombosis and/or pregnancy morbidity with persistent presence of anti-phospholipid antibodies (aPL).
Chayoua, Walid, de Laat, Bas, Devreese, Katrien, Fontana, Pierre, Gianniello, Francesca, Gris, Jean-Christophe, Kelchtermans, Hilde, Moore, Gary W, Musial, Jacek, Remijn, Jasper, Urbanus, Rolf T, Wahl, Denis, Zuily, Stéphane   +12 more
core   +4 more sources

Anticardiolipin antibodies and coronary heart disease [PDF]

, 2017
Arterial or venous thrombotic events have been described as complications in patients with positive anticardiolipin antibodies (aCL), affecting various organs including the heart.
BURKART, F., DUCKERT, F., MARBET, G. A., TSAKIRIS, D. A.   +3 more
core