Results 111 to 120 of about 715,175 (219)

Risk of Delayed Post‐polypectomy Bleeding in Patients With Antithrombotic Therapy

DEN Open, Volume 7, Issue 1, April 2027.
Antithrombotic therapy is associated with an increased risk of delayed post‐polypectomy bleeding after endoscopic resection of colorectal polyps ≤15 mm. Despite this increased risk, overall bleeding rates remain low in both per‐patient and per‐lesion analyses. ABSTRACT Objectives Recent changes in the perioperative management of antithrombotic therapy (
Rumiko Tsuboi, Satohiro Matsumoto, Makiko Mieno, Shizukiyo Ishikawa, Yurika Imai, Mina Morino, Keita Matsumoto, Yudai Koito, Hitomi Kashima, Takaya Miura, Yuko Takahashi, Takehiro Ishii, Shuhei Yoshikawa, Haruka Otake, Masanari Sekine, Takeshi Uehara, Takeharu Asano, Hiroyuki Miyatani, Hirosato Mashima   +18 more
wiley   +1 more source

Consensus Guidelines for Diagnosis and Management of Pyruvate Dehydrogenase Complex Deficiency

Journal of Inherited Metabolic Disease, Volume 49, Issue 6, November 2026.
ABSTRACT Primary pyruvate dehydrogenase complex deficiency (PDCD) comprises a group of monogenic disorders caused by pathogenic variants in genes encoding subunits of, or regulatory components affecting, the pyruvate dehydrogenase complex. The clinical phenotype spans a broad continuum, ranging from early onset congenital lactic acidosis to infantile ...
Nandaki Keshavan, Julia Neugebauer, Marcello Bellusci, Enrico Bertini, Garry Brown, Niklas Darin, Suzanne DeBrosse, Lucy Drexler, Stefan Drexler, Gregory M. Enns, Rebecca D. Ganetzky, Kelly Gilbert, Austin Larson, Rebecca Legi, April N. Lehman, Camile Newby, Manuel Schiff, Rachel Skeath, Peter W. Stacpoole, Sarah Thompson, Emma Watt, Saskia B. Wortmann, Jirair K. Bedoyan, Shamima Rahman   +23 more
wiley   +1 more source

Comments on the Anticholinergic Burden Calculator Web Tool.

Farmacia hospitalaria : organo oficial de expresion cientifica de la Sociedad Espanola de Farmacia Hospitalaria, 2019
-
Saioa Domingo-Echaburu, Unax Lertxundi-Etxebarria, Rafael Hernández-Palacios, Juan Medrano-Albéniz   +3 more
openaire   +2 more sources

Sex Differences in Prescribing Patterns of Anticholinergics and β3‐Adrenoceptor Agonists for Overactive Bladder: A Nationwide Study in Japan, FY2017–FY2024

LUTS: Lower Urinary Tract Symptoms, Volume 18, Issue 6, November 2026.
ABSTRACT Objectives Drug treatment for overactive bladder (OAB) is changing, with an increasing share of β3‐adrenoceptor agonists relative to anticholinergics, but it is not known how far this change has progressed in older people, who are most vulnerable to the risks of anticholinergics.
Toshikazu Koike, Takashi Kawahara, Akihito Hashizume, Masanobu Yamazaki, Daiji Takamoto, Hiroki Ito, Teppei Takeshima, Hiroji Uemura, Kazuhide Makiyama, Jun‐Ichi Teranishi   +9 more
wiley   +1 more source

[Anticholinergic burden in the elderly].

Farmaceuticos comunitarios
Anticholinergic drugs are widely used for very common diseases such as Parkinson's disease, depression or allergies, but it has been observed in previous studies that high anticholinergic burden can lead to physical and cognitive dysfunctions in polymedicated elderly people.
openaire   +1 more source

The Impact of Anticholinergic Burden on the Development of Mild Behavioral Impairment

The American Journal of Geriatric Psychiatry
Structured Abstract Objective Mild Behavioral Impairment (MBI) is a syndrome of late-life-onset persistent neuropsychiatric symptoms. Anticholinergic medication is commonly prescribed in older adults. Both MBI and anticholinergic exposure are associated with increased dementia risk.
Clio E. Franklin, Paul B. Rosenberg, Constantine G. Lyketsos, Zahinoor Ismail, Jeannie-Marie Leoutsakos   +4 more
openaire   +2 more sources

Gabapentinoids‐duloxetine combination therapy for chronic pain: A mechanism oriented rational to bridge theoretical knowledge and real life setting

British Journal of Clinical Pharmacology, Volume 92, Issue 10, Page 3333-3353, October 2026.
Chronic pain represents a complex debilitating condition that extends beyond the protective function of physiological pain, often persisting as an independent disease entity. Chronic primary and secondary pain syndromes reflect a multifaceted continuum involving nociceptive, neuropathic and nociplastic mechanisms.
Stefania Nobili, Maurizio Evangelista, Elena Lucarini, Elena G. Giugliano, Carla Ghelardini, Laura Micheli, Lorenzo Di Cesare Mannelli   +6 more
wiley   +1 more source

Antipsychotic Drug Interactions and Short‐Term Mortality Risk in People With Dementia: A National Cohort Study

Clinical Pharmacology &Therapeutics, Volume 120, Issue 4, Page 1081-1091, October 2026.
Antipsychotics are often prescribed in the management of behaviors and psychological symptoms of dementia. While the potential harms of antipsychotic use in people with dementia have been established, little is known about the risk associated with antipsychotic drug–drug interactions (DDIs). This study aims to examine the patterns of antipsychotic DDIs
Edward C.Y. Lau, Grace H. Shim, Chin Hang Yiu, Sarah N. Hilmer, Yun‐Hee Jeon, Weisi Chen, Christine Y. Lu, Edwin C.K. Tan   +7 more
wiley   +1 more source

Perianesthetic Complications in Genetic Mitochondrial Disease: A Review of Case Reports

Pediatric Anesthesia, Volume 36, Issue 10, Page 1217-1230, October 2026.
ABSTRACT Background Genetic mitochondrial diseases (GMDs) are a large group of genetically and clinically heterogeneous disorders caused by defects in genes encoding mitochondrial components. GMDs are grouped into named syndromes based on clinical presentation, for example, Leigh syndrome (LS).
Brittany M. Johnson, Simon C. Johnson
wiley   +1 more source

Anticholinergic burden in older adults

Introduction The world’s older population, often defined as people aged ≥65, is growing rapidly. With advancing age, there is an increased likelihood of adverse effects from medicines.

core   +1 more source