Results 111 to 120 of about 1,055,250 (236)

Antipsychotics‐Induced Hyposalivation Mediated by Impaired Salivary Ca2+ Signaling

Oral Diseases, EarlyView.
ABSTRACT Objectives Antipsychotic‐induced salivary dysfunction such as hyposalivation is a prevalent clinical challenge that severely compromises oral health and quality of life. Although typical and atypical antipsychotics have their therapeutic target in the central nervous system, their direct molecular mechanisms within the salivary glands remain ...
Chaelin Chung, Soohyun Kim, Yoo‐Bin Kim, Hee‐Kyung Park, Se‐Young Choi   +4 more
wiley   +1 more source

Anticholinergic drugs and dementia: time for transparency in the face of uncertainty. [PDF]

Cochrane Database Syst Rev, 2021
Woodford HJ, Stevenson JM.
europepmc   +1 more source

The drugs employed in the present investigation with their respective Anticholinergic Cognitive Burden (ACB) scores and Serum Anticholinergic Activity (SAA) scores.

, 2015
The drugs employed in the present investigation with their respective Anticholinergic Cognitive Burden (ACB) scores and Serum Anticholinergic Activity (SAA) scores.
G. Christopher Fox (698376), Erin H. Y. Tse (698374), Eric J. Hill (312830), H. Rheinallt Parri (324046), Michael D. Coleman (312824), Ian D. Maidment (698375), Elizabeth K. Woehrling (312828)   +6 more
core   +1 more source

Salivary Apelin Levels and Periodontal Findings in Individuals With/Without Type 1 Diabetes and Varying Degrees of Gingival Inflammation

Oral Diseases, EarlyView.
ABSTRACT Objective To evaluate salivary apelin levels in individuals with and without type 1 diabetes presenting an intact periodontium and varying degrees of plaque‐induced gingival inflammation. Methods Saliva samples were collected; and whole‐mouth clinical periodontal measurements were recorded in type 1 diabetes and systemically healthy ...
Demet Efe Yavaşoğlu, Andressa V. B. Nogueira, Mehmet Demirbaş, Timur Köse, Sebahat Kaya, James Deschner, Nurcan Buduneli   +6 more
wiley   +1 more source

Intestinal epithelial injury and inflammation after physical work in temperate and hot environments in older men with hypertension or type 2 diabetes

Experimental Physiology, EarlyView.
Abstract We tested whether older adults with well‐controlled type 2 diabetes or hypertension, compared with age‐matched adults without chronic disease, exhibit greater intestinal damage, microbial translocation and inflammation during exertional heat stress.
Ben J. Lee, Tessa R. Flood, Sophie L. Russell, James J. McCormick, Kelli E. King, Naoto Fujii, Tatsuro Amano, Sean Notley, Glen P. Kenny   +8 more
wiley   +1 more source

Effects of Anticholinergic Drugs on Visual Acuity of Patients with Tracheal Intubation under General Anesthesia. [PDF]

Dis Markers, 2022
Song J, Shen W, Cheng Y, Zheng Y.
europepmc   +1 more source

Non-degenerative mild cognitive impairment in elderly people and use of anticholinergic drugs: longitudinal cohort study.

, 2006
OBJECTIVE: To assess the potential of anticholinergic drugs as a cause of non-degenerative mild cognitive impairment in elderly people. DESIGN: Longitudinal cohort study.
Ritchie, Karen, A., Dupuy, Anne-Marie, Ancelin, Marie-Laure, Touchon, Jacques, Portet, Florence, Artero, Sylvaine   +5 more
core   +1 more source

Consensus Guidelines for Diagnosis and Management of Pyruvate Dehydrogenase Complex Deficiency

Journal of Inherited Metabolic Disease, Volume 49, Issue 6, November 2026.
ABSTRACT Primary pyruvate dehydrogenase complex deficiency (PDCD) comprises a group of monogenic disorders caused by pathogenic variants in genes encoding subunits of, or regulatory components affecting, the pyruvate dehydrogenase complex. The clinical phenotype spans a broad continuum, ranging from early onset congenital lactic acidosis to infantile ...
Nandaki Keshavan, Julia Neugebauer, Marcello Bellusci, Enrico Bertini, Garry Brown, Niklas Darin, Suzanne DeBrosse, Lucy Drexler, Stefan Drexler, Gregory M. Enns, Rebecca D. Ganetzky, Kelly Gilbert, Austin Larson, Rebecca Legi, April N. Lehman, Camile Newby, Manuel Schiff, Rachel Skeath, Peter W. Stacpoole, Sarah Thompson, Emma Watt, Saskia B. Wortmann, Jirair K. Bedoyan, Shamima Rahman   +23 more
wiley   +1 more source

Pharmacogenetic associations of CYP2D6 and CYP2C19 variants with anticholinergic drug burden and hyposalivation

Frontiers in Pharmacology
IntroductionAnticholinergic medications frequently cause hyposalivation (decreased saliva flow) through parasympathetic inhibition. This adverse effect is related to anticholinergic burden, reflecting the cumulative exposure to drugs with anticholinergic
Olga A. Korczeniewska, Scott Diehl, Abdul Basir Barmak, Tong Tong Wu, Eli Eliav, Szilvia Arany   +5 more
doaj   +1 more source

Influence of anticholinergic drugs on the development of an experimental periodontitis model. [PDF]

J Med Life, 2021
Batig VM, Kaskova LF, Ostafiichuk MA, Abramchuk II, Mytchenok MP, Karatintseva KP, Ishkov MO, Batih IV, Sheremet MI.   +8 more
europepmc   +1 more source