Results 131 to 140 of about 1,055,250 (236)

Perianesthetic Complications in Genetic Mitochondrial Disease: A Review of Case Reports

Pediatric Anesthesia, Volume 36, Issue 10, Page 1217-1230, October 2026.
ABSTRACT Background Genetic mitochondrial diseases (GMDs) are a large group of genetically and clinically heterogeneous disorders caused by defects in genes encoding mitochondrial components. GMDs are grouped into named syndromes based on clinical presentation, for example, Leigh syndrome (LS).
Brittany M. Johnson, Simon C. Johnson
wiley   +1 more source

Neuroleptic malignant syndrome after abrupt discontinuation of neuroleptic and anticholinergic drugs.

Ind Psychiatry J, 2023
Bhargava S, Bairwa K, Motwani Y.
europepmc   +1 more source

Brain Penetrant Calcium Channel Blockers Were Not Associated With Reduced Alcohol Consumption: Converging Results From Two Large Independent Cohort Studies Using Electronic Health Records

Pharmacoepidemiology and Drug Safety, Volume 35, Issue 10, October 2026.
ABSTRACT Purpose Alcohol use disorder (AUD) remains a major public health problem, with few effective treatments. L‐type calcium channel blockers (LTCCBs) have genetic and preclinical support as potential treatments for AUD. Methods We evaluated whether brain penetrant (BP)‐LTCCBs are associated with reduced alcohol consumption in two preregistered ...
Christopher T. Rentsch, Vanessa A. Palzes, Mingjian Shi, Michael R. Setzer, Samantha G. Malone, Andrea H. Kline‐Simon, Emma L. Winterlind, Lorenzo Leggio, Vincent Lo Re III, David A. Fiellin, John Tazare, Mehdi Farokhnia, Stacy Sterling, Henry R. Kranzler, Joshua C. Gray   +14 more
wiley   +1 more source

The cognitive effects of anticholinergic drugs on apolipoprotein ε4 carriers and noncarriers in the Wisconsin Registry for Alzheimer's Prevention study. [PDF]

Neuropsychology, 2021
Collin BG, Raju D, Katsikas S.
europepmc   +1 more source

Development of a Brazilian anticholinergic activity drug scale

, 2019
Objective To develop a scale of anticholinergic activity drugs used in Brazil, to be applied in health care and pharmacoepidemiology research. Methods We performed a literature review on PubMed/MEDLINE® to identify previously published scales of ...
Adriano Max Moreira Reis (4827153), Raiany Thaimeny Nery (6544454)   +1 more
core   +1 more source

Improving Medication Management in Indonesian Aged Care Homes: Research Priority Setting With Stakeholders

Pharmacology Research &Perspectives, Volume 14, Issue 5, October 2026.
ABSTRACT Indonesia and other Southeast Asian nations are experiencing rapidly aging populations. The Indonesian Government recently announced a national initiative of aged care homes to support older people not able to live independently or receive family care.
Yulisna Mutia Sari, J. Simon Bell, Surya Adhi, Uswa Alhamid, Esthika Dewiasty, Annisa Dhanira, Clara M. Kusharto, Evi Dwi Novriany, Dion Notario, Imran Pambudi, Rocksy Situmeang, Sri Soenarti, M. Rizky Widodo, Grace Wangge   +13 more
wiley   +1 more source

Prenatal findings and postnatal outcomes in cases of closed spinal dysraphism: 10‐year two‐center cohort study

Ultrasound in Obstetrics &Gynecology, Volume 68, Issue 4, Page 518-526, October 2026.
ABSTRACT ObjectiveTo characterize prenatal ultrasound findings in fetuses with prenatally diagnosed closed spinal dysraphism (CSD) and report their postnatal management and functional outcomes at 18 and 36 months. MethodsThis retrospective cohort study included all fetuses with a prenatal diagnosis of CSD assessed between January 2014 and December 2024
Y. Athiel, E. Van den Eede, T. de Saint Denis, E. Blondiaux, F. Dhombres, P. Maurice, A. Dugas, H. Simonnet, L. Guilbaud, C. Garel, H. van der Merwe, M. Aertsen, P. Devloo, R. Devlieger, J. Deprest, J.‐M. Jouannic   +15 more
wiley   +1 more source

Dualsteric and dual‐acting modulation of muscarinic receptors by antagonist KH‐5

British Journal of Pharmacology, Volume 183, Issue 19, Page 5769-5790, October 2026.
Abstract Background and purpose Muscarinic acetylcholine receptors are key therapeutic targets, and ligands engaging both orthosteric and allosteric sites may offer improved selectivity and efficacy. Here, we investigated whether the muscarinic antagonist KH‐5 acts as a dualsteric antagonist and defined its mode of interaction with muscarinic receptors.
Alena Janoušková‐Randáková, Eva Dolejší, Nikolai Chetverikov, Jan Jakubík   +3 more
wiley   +1 more source

National Drugs Advisory Board annual report, 1986

, 1986
The National Drugs Advisory Board was established by the Minister for Health in 1966 by the National Drugs Advisory Board (Establishment) Order 1966 (5.1. No. 163·of 1966) under the Health (Corporate Bodies) Act 1961.
National Drugs Advisory Board (NDAB)
core  

Muscarinic agonists for schizophrenia: Bridging preclinical evidence and clinical enthusiasm

British Journal of Pharmacology, Volume 183, Issue 19, Page 5701-5731, October 2026.
Abstract Antipsychotic drugs targeting dopamine receptors have been used to treat schizophrenia for decades, primarily alleviating positive symptoms such as hallucinations and delusions. However, they provide limited benefit for cognitive and negative symptoms—major contributors to poor outcomes—and are frequently associated with significant side ...
Brian J. Morris, Judith A. Pratt
wiley   +1 more source