Results 111 to 120 of about 322,983 (366)

Online Learning to Estimate Warfarin Dose with Contextual Linear Bandits [PDF]

open access: yesarXiv, 2019
Warfarin is one of the most commonly used oral blood anticoagulant agent in the world, the proper dose of Warfarin is difficult to establish not only because it is substantially variant among patients, but also adverse even severe consequences of taking an incorrect dose.
arxiv  

STUDI PENGGUNAAN ANTIKOAGULAN PADA PASIEN INFARK MIOKARD AKUT [PDF]

open access: yes
Background : Acute Myocardial Infarction (AMI) is myocardial necrosis caused by an imbalance in oxygen and blood supply resulting from an acute blockage of the coronary arteries. Rupture of atheroma plaque in the coronary arteries, followed by thrombosis,
Yanti, Jesica Kharisma
core  

Evidence of Songbird Intoxication From Rozol Application at a Black-Tailed Prairie Dog Colony [PDF]

open access: yes, 2013
Concerns about avian poisonings from anticoagulant rodenticides have traditionally focused on secondary poisoning of raptors exposed by feeding on contaminated mammalian prey.
Hulse, Craig S.   +3 more
core   +1 more source

Anticoagulation in practice

open access: yesMedicine, 2000
Abstract Anticoagulation prevents pathological clot formation (e.g. on heart valves or chambers) and stops propagation and embolization of clots already developed in veins. The type, intensity and duration of anticoagulation depend on the indication. About 1.8% of the UK population requires anticoagulation. The two main anticoagulant drugs are heparin
openaire   +2 more sources

Dual‐Atom Catalyst Au@S‐rGO for Rapid and Highly Sensitive Electrochemical Detection of Fentanyl in Serum

open access: yesAdvanced Science, EarlyView.
This study develops an Au/S‐doped reduced graphene oxide (Au@S‐rGO) sensor for rapid fentanyl detection. DFT simulations and structural analysis confirm atomically dispersed Au/S configurations, enhancing catalytic activity. The sensor achieves a 9.7 nmol L−1 detection limit, 98–104% recovery in human serum, and 85.7–93.6% consistency with mass ...
Meng Li   +9 more
wiley   +1 more source

State of plasma hemostasis in patients with hypertension in combination with non-alcoholic fatty liver disease

open access: yesJournal of Education, Health and Sport, 2018
Background. Among liver diseases, non-alcoholic fatty liver disease (NAFLD) is the most common. NAFLD is an independent risk factor for the development and progression of cardiovascular diseases. Objective.
N. Bazhenova
doaj  

Idarucizumab for Dabigatran Reversal - Full Cohort Analysis. [PDF]

open access: yes, 2017
BACKGROUND: Idarucizumab, a monoclonal antibody fragment, was developed to reverse the anticoagulant effect of dabigatran. METHODS: We performed a multicenter, prospective, open-label study to determine whether 5 g of intravenous idarucizumab would be ...
Bernstein, Richard A.   +20 more
core   +1 more source

Bench-to-bedside review: the role of activated protein C in maintaining endothelial tight junction function and its relationship to organ injury. [PDF]

open access: yes, 2006
Activated protein C (APC) has emerged as a novel therapeutic agent for use in selected patients with severe sepsis, even though the mechanism of its benefit is not well established.
Looney, Mark R, Matthay, Michael A
core   +2 more sources

Identification of CD38high Monocyte as a Candidate Diagnostic Biomarker and Therapeutic Target for Sepsis

open access: yesAdvanced Science, EarlyView.
This study uncovers that CD38high monocytes discriminate sepsis and sterile inflammation and are associated with 28‐day mortality in bacterial sepsis. Targeting CD38 therapy reduces inflammatory response in monocytes and in sepsis mice model. Mechanistically, CD38‐HIF‐1α/glycolysis/MGO loop exacerbates sepsis‐induced immune dysregulation.
Ning Hua   +19 more
wiley   +1 more source

Mechanical Biomimetic Nanocomposites for Multidimensional Treatment of Arterial Thrombosis

open access: yesAdvanced Science, EarlyView.
In this study, a mechanical biomimetic nanocomposite is developed, guided by photoacoustic imaging, to achieve highly efficient and safe thrombolysis through the synergistic effects of photothermal therapy and pharmacological intervention. Most notably, the nanoparticle improves the microenvironment of arterial thrombi, marked by high shear stress and ...
Ying Li   +6 more
wiley   +1 more source

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