Results 111 to 120 of about 464,460 (389)

Heparin Mimetics: Their Therapeutic Potential

open access: yesPharmaceuticals, 2017
Heparin mimetics are synthetic and semi-synthetic compounds that are highly sulfated, structurally distinct analogues of glycosaminoglycans. These mimetics are often rationally designed to increase potency and binding selectivity towards specific ...
Shifaza Mohamed, Deirdre R. Coombe
doaj   +1 more source

Anticoagulant-Related Nephropathy.

open access: yesJournal of the American Society of Nephrology, 2018
Anticoagulant-related nephropathy (ARN) is a newly recognized form of AKI in which overanticoagulation causes profuse glomerular hemorrhage, which manifests on renal biopsy as numerous renal tubules filled with red cells and red cell casts. The glomeruli
S. Brodsky, J. Eikelboom, L. Hebert
semanticscholar   +1 more source

Magnetically Controlled Reversible Photomagnetic Nanoactuators for Dynamic Contrast Enhancement in Optical Coherence Tomography

open access: yesAdvanced Materials, EarlyView.
Photomagnetic nanoactuators with ≈90% scattering efficiency in the second near‐infrared window are demonstrated to exhibit magnetic field‐controlled modulation of optical scattering and optical coherence tomography signals. These nanoactuators are reversibly assembled and disassembled under the external magnetic field modulation, enabling enhanced ...
Myeongsoo Kim   +5 more
wiley   +1 more source

An Albumin-Oligonucleotide Assembly for Potential Combinatorial Drug Delivery and Half-Life Extension Applications

open access: yesMolecular Therapy: Nucleic Acids, 2017
The long blood circulatory property of human serum albumin, due to engagement with the cellular recycling neonatal Fc receptor (FcRn), is an attractive drug half-life extension enabling technology. This work describes a novel site-specific albumin double-
Matthias Kuhlmann   +12 more
doaj   +1 more source

Materials Advances in Devices for Heart Disease Interventions

open access: yesAdvanced Materials, EarlyView.
This review examines the crucial role of materials in heart disease interventions, focusing on strategies for monitoring, managing, and repairing heart conditions. It discusses the material requirements for medical devices, highlighting recent innovations and their impact on cardiovascular health.
Gagan K. Jalandhra   +11 more
wiley   +1 more source

Choosing a particular oral anticoagulant and dose for stroke prevention in individual patients with non-valvular atrial fibrillation: part 2.

open access: yesEuropean Heart Journal, 2016
The choice of oral anticoagulant (OAC) for patients with atrial fibrillation (AF) may be influenced by individual clinical features or by patterns of risk factors and comorbidities.
H. Diener   +15 more
semanticscholar   +1 more source

Bioinspired Smart Nanogels for Rapid Blue Laser‐Activated Hemostasis in Gastrointestinal Bleeding

open access: yesAdvanced Materials, EarlyView.
Waxberry‐inspired branched‐silica nanogel can swiftly stop bleeding upon blue laser endoscopy for gastrointestinal hemostasis in the esophagus, stomach, and duodenum of mini‐pigs. Abstract Gastrointestinal bleeding (GIB) is a critical condition that requires rapid and effective intervention.
Ruijue Dan   +12 more
wiley   +1 more source

Anticoagulant baiting for jackrabbit control [PDF]

open access: yes, 1978
The jackrabbit, Lepus californicus, is properly called a hare rather than a rabbit, because the young are born fully furred and with eyes open. Hares differ from rabbits in anatomy and in the lack of burrowing, although individual hares often have a more
Johnston, John C.
core   +1 more source

Dental management considerations for the patient with an acquired coagulopathy. Part 1: Coagulopathies from systemic disease [PDF]

open access: yes, 2003
Current teaching suggests that many patients are at risk for prolonged bleeding during and following invasive dental procedures, due to an acquired coagulopathy from systemic disease and/or from medications.
A Barber   +90 more
core   +1 more source

Benefit profile of anticoagulant therapy in sepsis: a nationwide multicentre registry in Japan

open access: yesCritical Care, 2016
BackgroundLittle evidence supports anticoagulant therapy as effective adjuvant therapy to reduce mortality overall in sepsis. However, several studies suggest that anticoagulant therapy may reduce mortality in specific patients.
K. Yamakawa   +8 more
semanticscholar   +1 more source

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