Results 141 to 150 of about 482,975 (382)

Magnetically‐Induced Suppression of Oxidative Stress Prevents Venous Thrombosis

Advanced Science, EarlyView.
Venous thromboembolism (VTE) remains a leading cause of cardiovascular mortality. This study demonstrates that static magnetic fields (SMF) offer a novel non‐pharmacological intervention against VTE by mitigating endothelial oxidative stress. Mechanistically, SMF elevates intracellular Ca2+, boosts ATP production, and suppresses NOX4‐mediated ROS ...
Nana Zhang, Yirong An, Shiran Tao, Shenao Qu, Minge Wu, Guantong Fang, Ziqing Chen, Weilun Song, Haoze Leng, Rongqian Wu, Yi Lyu, Xiaoli Liu, Dinghui Dong   +12 more
wiley   +1 more source

Prevalence, Characteristics, and Outcomes of Valvular Heart Disease in Patients With Atrial Fibrillation: Insights From the ORBIT‐AF (Outcomes Registry for Better Informed Treatment for Atrial Fibrillation)

Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, 2017
BackgroundThe presence of valvular heart disease (VHD) may affect the risk of stroke and mortality in patients with atrial fibrillation (AF). Community‐based estimates of prevalence and outcomes of specific forms of VHD in patients with AF are lacking ...
Kevin L. Thomas, Larry R. Jackson, Peter Shrader, Jack Ansell, Gregg C. Fonarow, Bernard Gersh, Peter R. Kowey, Kenneth W. Mahaffey, Daniel E. Singer, Laine Thomas, Jonathan P. Piccini, Eric D. Peterson   +11 more
doaj   +1 more source

Inhibition of heparanase-mediated degradation of extracellular matrix heparan sulfate by non-anticoagulant heparin species [PDF]

, 1987
M Bar-Ner, Amiram Eldor, L Wasserman, Y Matzner, Cohen Ir, Zvi Fuks, I Vlodavsky   +6 more
openalex   +1 more source

Use of tramadol and the risk of bleeding complications in patients on oral anticoagulants: a systematic review and meta-analysis

, 2022
Clara Lévy, Laëtitia Gosselin, Ana‐Maria Vilcu, Olivier Steichen   +3 more
openalex   +2 more sources

Targeted 2‐Deoxy‐D‐Ribose Delivery by Biomimetic Nanoplatform Activates EGFR for Accelerated Heart Valve Endothelialization

Advanced Science, EarlyView.
This study develops a biomimetic nanoplatform using erythrocyte membrane‐camouflaged, CD144 antibody‐functionalized nanoparticles to deliver 2‐deoxy‐D‐ribose (2dDR). This system promotes heart valve endothelialization by enhancing endothelial cell migration and proliferation via EGFR activation, while improving hemocompatibility.
Xiang Qiu, Gaofeng Li, Wenyi Wan, Jinsheng Li, Ge Yan, Shijie Wang, Xiuqi Hu, Zongqi Han, Yazheng Shan, Ying Zhou, Nianguo Dong, Weihua Qiao   +11 more
wiley   +1 more source

State of plasma hemostasis in patients with hypertension in combination with non-alcoholic fatty liver disease

Journal of Education, Health and Sport, 2018
Background. Among liver diseases, non-alcoholic fatty liver disease (NAFLD) is the most common. NAFLD is an independent risk factor for the development and progression of cardiovascular diseases. Objective.
N. Bazhenova
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Prior Direct Oral Anticoagulant Therapy is Related to Small Infarct Volume and No Major Artery Occlusion in Patients With Stroke and Non‐Valvular Atrial Fibrillation

Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, 2018
Background The aims of the present study were to investigate the relationships between prior direct oral anticoagulant (DOAC) therapy and infarct volume and the site of arterial occlusion in patients with acute ischemic stroke and non‐valvular atrial ...
Yuki Sakamoto, Seiji Okubo, Tetsuro Sekine, Chikako Nito, Satoshi Suda, Noriko Matsumoto, Yasuhiro Nishiyama, Junya Aoki, Takashi Shimoyama, Takuya Kanamaru, Kentaro Suzuki, Masahiro Mishina, Kazumi Kimura   +12 more
doaj   +1 more source

In-hospital Bleeding Outcomes of Oral Anticoagulant and Dual Antiplatelet Therapy During Percutaneous Coronary Intervention: An Analysis From the Japanese Nationwide Registry

, 2021
Fumiaki Yashima, Taku Inohara, Hiroaki Nishida, Kenichiro Shimoji, Koji Ueno, Shigetaka Noma, Kyohei Yamaji, Hideki Ishii, Nobuhiro Tanaka, Shun Kohsaka, Tetsuya Amano, Yuji Ikari   +11 more
openalex   +1 more source

Targeting G3BP1 Condensate Topology Promotes Stress Granule Assembly via m6A‐IGF2BP1 for Ischemic Stroke Rescue

Advanced Science, EarlyView.
Our research reveals that small‐molecule icariin (ICA) directly binds Ras‐GTPase‐activating protein SH3 domain‐binding protein 1 (G3BP1), inducing conformational change and oligomerization. This interaction confers neuroprotection by recruiting insulin‐like growth factor 2 mRNA‐binding protein 1 (IGF2BP1) and modulating N6‐methyladenosine (m6A ...
Ling Li, Yong‐Dong Guo, Xiao‐Wen Zhang, Zhi‐Yong Du, Yu‐Qi Wang, Zhuo Yang, Qian‐Wei Luo, Fang‐Fang Zhuo, Tian‐Tian Wei, Zheng‐Ping Liu, Bo Han, Wei Yu, Pei‐Pei Zhang, Wei Zhou, Zhi‐Yuan Lu, Peng‐Fei Tu, Chun‐Hong Zheng, Ke‐Wu Zeng   +17 more
wiley   +1 more source

Successful treatment of massive thrombosis of the vena cava inferior with nephrоtic syndrome and chronic bilateral pulmonary artery thromboembolism in a patient with genetic thrombophilia

Терапевтический архив, 2012
A case is reported of a 23-year-old male patient who developed, after severe blunt injury of the lumbar region, massive thrombosis of the vena cava inferior (VCI), both renal veins, bilateral pulmonary artery thromboembolism (PATE), nephrоtic syndrome ...
Ol'ga Vladimirovna Blagova, S L Dzemeshkevich, N L Kozlovskaya, A V Nedostup, N D Sarkisova, Yu V Frolova, V V Raskin, A S Dzemeshkevich, S A Abugov, O G Skipenko, E M Shilov, V P Sedov, N V Gagarina, V E Sinitsyn, E A Mershina, E Yu Volkova, O V Blagova, S L Dzemeshkevich, N L Kozlovskaya, A V Nedostup, N D Sarkisova, Yu V Frolova, V V Raskin, A S Dzemeshkevich, S A Abugov, O G Skipenko, E M Shilov, V P Sedov, N V Gagarina, V E Sinitsyn, E A Mershina, E Yu Volkova   +31 more
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