Results 161 to 170 of about 467,565 (384)

Red Blood Cell Membrane Lipidomics: Potential Biomarkers Detecting Method for Plasma Volume Overload and Major Adverse Cardiovascular Events in Chronic Heart Failure Patients

open access: yesAdvanced Science, EarlyView.
A novel RBC indicator, ESI, is better than the traditional RBC indicators and is associated with CHF prevalence and in‐hospital death. RBC membrane lipidomics, Cer 18:0;O2/16:0, and LPE 18:0, are associated with plasma volume overload and MACE in CHF patients, but these plasma lipids could not.
Lin Zhang   +12 more
wiley   +1 more source

A Multi‐Property Optimizing Generative Adversarial Network for de novo Antimicrobial Peptide Design

open access: yesAdvanced Science, EarlyView.
A Multi‐Property Optimizing Generative Adversarial Network (MPOGAN) is proposed to iteratively learn the relationship between peptides and multiple properties using a dynamically dataset. As the quality of the dataset improves, MPOGAN's ability to design antimicrobial peptides (AMPs) with multiple desired properties is enhanced.
Jiaming Liu   +16 more
wiley   +1 more source

Editorial: Venous thromboembolism and pregnancy

open access: yesFrontiers in Cardiovascular Medicine, 2022
Bernard Tardy, Laurent Bertoletti
doaj   +1 more source

Deciphering the Role and Mechanism of Decidual Monocyte‐Derived Macrophage Infiltration in Obstetric Antiphospholipid Syndrome at Single‐Cell Resolution

open access: yesAdvanced Science, EarlyView.
This study uncovers a novel mechanism and therapeutic targets in obstetric antiphospholipid syndrome (OAPS). Antiphospholipid antibody/ß2‐glycoprotein I complex boosts CCL2 and TNF‐α expression in decidual macrophages via TLR4‐NF‐κB. CCL2 accumulates on endothelial surfaces via ACKR1, recruiting monocyte‐derived CCR2+ macrophages, driving inflammation,
Rui Gao   +13 more
wiley   +1 more source

In Situ Programming of the Tumor Microenvironment to Alleviate Immunosuppression for Pancreatic Cancer Immunotherapy

open access: yesAdvanced Science, EarlyView.
cmExoaCD11b induced the repolarization of immunosuppressive M2 macrophages into pro‐inflammatory M1 phenotype, thereby promoting the proliferation and activation of CD8+ T cells and reversing the immunosuppressive state of the tumor microenvironment.
Man Sun   +14 more
wiley   +1 more source

Preliminary Report on the Clinical Use of a New Anticoagulant, Phenylindandione [PDF]

open access: bronze, 1950
ANCEL U. BLAUSTEIN   +3 more
openalex   +1 more source

Anticoagulation

open access: yes
This chapter aims to summarize the most relevant aspects of anticoagulants. Initially, a brief review of the physiology is given in order to understand at which step of coagulation each anticoagulant acts. Later, the main indications and contraindications will be discussed, as well as the considerations that should be taken into account before starting
Hernando, Nieto, Raquel   +5 more
openaire   +2 more sources

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