Results 11 to 20 of about 322,983 (366)

Machine Learning for Prediction of Stable Warfarin Dose in US Latinos and Latin Americans

Frontiers in Pharmacology, 2021
Populations used to create warfarin dose prediction algorithms largely lacked participants reporting Hispanic or Latino ethnicity. While previous research suggests nonlinear modeling improves warfarin dose prediction, this research has mainly focused on ...
Heidi E. Steiner, Jason B. Giles, Hayley Knight Patterson, Jianglin Feng, Nihal El Rouby, Karla Claudio, Karla Claudio, Leiliane Rodrigues Marcatto, Leticia Camargo Tavares, Leticia Camargo Tavares, Jubby Marcela Galvez, Carlos-Alberto Calderon-Ospina, Xiaoxiao Sun, Mara H. Hutz, Stuart A. Scott, Larisa H. Cavallari, Dora Janeth Fonseca-Mendoza, Jorge Duconge, Mariana Rodrigues Botton, Mariana Rodrigues Botton, Paulo Caleb Junior Lima Santos, Paulo Caleb Junior Lima Santos, Jason H. Karnes, Jason H. Karnes   +23 more
doaj   +1 more source

Comparison of circuit patency and exchange rates between the original and generic versions of nafamostat mesylate in critically ill adults receiving continuous renal replacement therapy [PDF]

Kosin Medical Journal, 2023
Background Nafamostat mesylate is widely used as an anticoagulant in continuous renal replacement therapy (CRRT). The generic versions of nafamostat mesylate have identical main components to the original product.
Sujung Heo, Yanghyeon Kim, Nagyeom Lee, Ye Na Kim, Ho Sik Shin, Yeonsoon Jung, Hark Rim   +6 more
doaj   +1 more source

Risk Stratification Using the CHA2DS2‐VASc Score in Takotsubo Syndrome: Data From the Takotsubo Italian Network

Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, 2017
BackgroundThe CHA2DS2‐VASc score predicts stroke in patients with atrial fibrillation and has been reported to have a prognostic role even in acute coronary syndrome patients.
Guido Parodi, Fernando Scudiero, Rodolfo Citro, Angelo Silverio, Benedetta Bellandi, Concetta Zito, Francesco Antonini‐Canterin, Fausto Rigo, Chiara Zocchi, Eduardo Bossone, Jorge Salerno‐Uriarte, Federico Piscione, Carlo Di Mario   +12 more
doaj   +1 more source

Evidence supporting idarucizumab for the reversal of dabigatran. [PDF]

, 2016
Idarucizumab is a monoclonal antibody fragment specifically targeted to dabigatran. It has demonstrated prompt and durable reversal of the anticoagulant effects of dabigatran in animal studies and phase 1 studies of young, elderly, and renally impaired ...
Pollack, Charles V.
core   +2 more sources

Prior Direct Oral Anticoagulant Therapy is Related to Small Infarct Volume and No Major Artery Occlusion in Patients With Stroke and Non‐Valvular Atrial Fibrillation

Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, 2018
Background The aims of the present study were to investigate the relationships between prior direct oral anticoagulant (DOAC) therapy and infarct volume and the site of arterial occlusion in patients with acute ischemic stroke and non‐valvular atrial ...
Yuki Sakamoto, Seiji Okubo, Tetsuro Sekine, Chikako Nito, Satoshi Suda, Noriko Matsumoto, Yasuhiro Nishiyama, Junya Aoki, Takashi Shimoyama, Takuya Kanamaru, Kentaro Suzuki, Masahiro Mishina, Kazumi Kimura   +12 more
doaj   +1 more source

Life‐threatening extrapleural hematoma in an anticoagulated patient 2 weeks after lobectomy

Thoracic Cancer, 2021
We report a case of an anticoagulated patient with sudden onset pleural hematoma after straining at defecation to cardiac arrest on 2 weeks after lobectomy for lung cancer.
Masanori Shimomura, Masashi Iwasaki, Reona Shimegi, Masayoshi Inoue   +3 more
doaj   +1 more source

Anticoagulants [PDF]

Journal of Pharmacy and Pharmacology, 1949
Abstract The processes that underly the clotting of blood are still far from adequately understood, in spite of the many facts uncovered by generations of patient investigators. The classical scheme associated with the name of Morawitz1, although neither complete nor universally accepted, is still useful as a summary of the main events ...
openaire   +3 more sources

Prevalence, Characteristics, and Outcomes of Valvular Heart Disease in Patients With Atrial Fibrillation: Insights From the ORBIT‐AF (Outcomes Registry for Better Informed Treatment for Atrial Fibrillation)

Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, 2017
BackgroundThe presence of valvular heart disease (VHD) may affect the risk of stroke and mortality in patients with atrial fibrillation (AF). Community‐based estimates of prevalence and outcomes of specific forms of VHD in patients with AF are lacking ...
Kevin L. Thomas, Larry R. Jackson, Peter Shrader, Jack Ansell, Gregg C. Fonarow, Bernard Gersh, Peter R. Kowey, Kenneth W. Mahaffey, Daniel E. Singer, Laine Thomas, Jonathan P. Piccini, Eric D. Peterson   +11 more
doaj   +1 more source

First-In-Human Study to Assess the Safety, Pharmacokinetics, and Pharmacodynamics of SHR2285, a Small-Molecule Factor XIa Inhibitor in Healthy Subjects

Frontiers in Pharmacology, 2022
Background: Targeting factor XI (FXI) is a promising therapeutic strategy for the treatment and prevention of thrombosis without increasing the risk of bleeding. Here, we assessed the safety, pharmacokinetics (PK), and pharmacodynamics (PD) of SHR2285, a
Rui Chen, Xiaoduo Guan, Pei Hu, Yanli Dong, Yi Zhu, Tengfei Zhang, Jianjun Zou, Shuyang Zhang   +7 more
doaj   +1 more source

Medial Collateral Ligament Knee Injury in a Patient Receiving Rivaroxaban: A Cause of Acute Hemarthrosis [PDF]

Reviews in Clinical Medicine, 2020
Medial collateral ligament (MCL) injury is highly common in athletes and the elderly. This ligament is in the knee region and is often at the risk of injury.
Seyed Reza Habibzadeh, Mahdi Foroughian, Esmaeil Rayat Dost   +2 more
doaj   +1 more source